A new form of Kaposi sarcoma arising in treated people living with HIV
Kaposi sarcoma, a skin cancer caused by herpesvirus-8, develops in the context of immunosuppression or aging. In people living with HIV, Kaposi sarcoma is considered as a harbinger of AIDS and its incidence decreased with the advent of antiretroviral treatments. However, cases re-emerge in HIV-treated people, re-exposing the stigma of AIDS and suggesting an influence of senescence. In their latest article in the AIDS Journal, MCVD member Dr. Jean-Pierre Routy and his co-researcher Dr. Léna Royston report this new form of the disease and are implementing a study in HIV-infected and elderly individuals to understand the mechanisms involved, and develop novel therapies.