Meet our board members
Paul François (acting director)
Paul François is an Associate Professor in the Physics Department at McGill University. His research focuses on the development of theoretical and numerical methods to study biological dynamics at all scales, from the immune system to developing embryos.
Adam Hendricks is an Assistant Professor of Bioengineering at McGill University. His lab seeks to understand how motor proteins transport intracellular cargoes, assemble the mitotic spindle, and tune cellular mechanics. Towards this goal, his lab develops biophysical tools to image and manipulate single motor proteins in living cells and reconstituted in vitro systems. Email: adam.hendricks [at] mcgill.ca
Dr. Rodrigo Reyes is a pioneer in the use of single-molecule microscopy in live cells for the study of macromolecular machines. He joined the Department of Biology at McGill in March of 2013 as an Assistant Professor, and he is currently a Canada Research Chair Tier II in Chromosome Biology.
The work in the Reyes lab aims to understand the composition, architecture and activity of molecular machines as they work in the cell. Their research addresses the fact that the intracellular environment is too complex to be accurately reproduced in test tubes. Therefore, they develop and use advanced fluorescence microscopy techniques to quantify cellular activities in genetically tractable “simple” organisms. The focus of their team is the study of DNA replication, which is both the most active guardian against genetic mutations and the most frequent source of genomic instability. An incomplete understanding of the molecular machine that carries out DNA replication, the replisome, is a major impediment to understanding its role in health and disease. The approach they use makes their research unique among groups studying DNA replication.
Steph Weber is an Assistant Professor in Biology and an Associate Member in Physics. Her lab uses quantitative live-cell imaging and physical modelling to understand how biological systems establish and dynamically regulate spatial organization across length scales.
She’s particularly interested in determining how intracellular phase transitions impact the growth, size and health of whole organisms.
Paul Wiseman’s research interests lie at the interface between the physical and biological sciences. His work focuses on understanding the molecular mechanisms involved in how cells adhere to other cells and surfaces, and how cells regulate this adhesion to control cellular migration as well as cell signaling. He is also interested in developing new fluorescence fluctuation–based biophysical methods, such as image correlation spectroscopy and spatial intensity distribution analysis, to map protein transport and interactions in cells in combination with fluorescence microscopy and super-resolution nanoscopy imaging.Wiseman is also working on the application of nonlinear imaging modalities, such as second and third harmonic generation (SHG and THG) microscopy, for live cell and fixed tissue imaging.