Publications

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2020

Mayo. N.E., Brouillette, M.J., Scott, S.C., Harris, M., Smaill, F., Smith, G., Thomas, R., Fellows, L.K., & investigators from the Positive Brain Health Now Study. (2020) Relationships between cognition, function, and quality of life among HIV+ Canadian men, Qual Life Res, 29(1):37-55. doi: 10.1007/s11136-019-02291-w

2019

Fellows, L.K. (2019) The functions of the frontal lobes : Evidence from patients with focal brain damageHandb Clin Neurol, 163:19-34.

Fellows, L.K. (2019) Remembering to choose the futureElife, doi: 10.7554/eLife.49828.

Vaidya, A.R., Pujara, M.S., Petrides, M., Murray, E.A., & Fellows, L.K. (2019) Lesion Studies in Contemporary NeuroscienceTrends Cogn Sci, 23(8):653-671.

Kaur, N., Dendukuri, N., Fellows, L.K., Brouillette, M.J., & Mayo, N. (2019) Association between cognitive reserve and cognitive performance in people with HIV: a systematic review and meta-analysis, AIDS Care, doi: 10.1080/09540121.2019.1612017.

Brouillette, M.J., Fellows, L.K., Finch, L., Thomas, R., & Mayo, N.E. (2019) Properties of a brief assessment tool for longitudinal measurement of cognition in people living with HIVPLoS One, 14(3):e0213908.

Sanford, R., Strain, J., Dadar, M., Maranzano, J., Bonnet, A., Mayo, NE., Scott, SC., Fellows, L.K., Ances, B.M., & Collins, D.L. (2019) HIV infection and cerebral small vessel disease are independently associated with brain atrophy and cognitive impairmentAIDS, 33(7):1197-1205.

Pelletier, G., & Fellows, L.K. (2019)  A critical role for human ventromedial frontal lobe in value comparison of complex objects based on attribute configurationJ. Neurosci, 39(21):4124-4123.

Illes, J., Weiss, S., Bains, J., Chandler, J.A., Conrod, P., De Koninck, Y., Fellows, L.K., Groetzinger, D., Racine, E., Robillard, J.M., & Sokolowski, M.B. (2019) A neuroethics backbone for the evolving canadian brain research strategyNeuron, 101(3):370-374.

Vaidya, A.R., & Fellows, L.K. (2019) Ventromedial frontal lobe damage affects interpretation, not exploration, of emotional facial expressionsCortex, 101(3):370-374.

Aridan, N., Pelletier, G., Fellows, L.K., & Schonberg, T. (2019) Is ventromedial prefrontal cortex critical for behavioral change without external reinforcement?Neurospychologia, 124:208-215.

Lam, A., Mayo, N.E., Scott, S., Brouillette, M.J., & Fellows, L.K. (2019) HIV-related stigma affects cognition in older men living with HIVJ Acquir Immune Defic Syndr, 80(2):198-204.

 

2018

Dahmani, L., Patel, R.M., Yang, Y., Chakravarty, M.M., Fellows, L.K., & Bohbot, V.D. (2018) An instrinsic association between olfactory identification and spatial memory in humansNat Commun, 9(1):4162.

Mayo, N.E., Brouillette, M.J., & Fellows, L.K. (2018) Estimates of prevalence of cognitive impairment from research studies can be affected by selection biasJ. Acquir Immune Defic Syndr, 78(2):e7-e8

Noonan, M.P., Mars, R.B., Sallet, J., Dunbar, R.I.M., & Fellows, L.K. (2018) The structural and functional brain networks that support human social networksBehav Brain Res, 355:12-23.

Sanford, R., Fellows, L.K., Ances, B.M., Collins, D.L. (2018) Association of brain structure changes and cognitive function with combination antiretroviral therapy in HIV-positive individualsJAMA Neurol75(1):72-79.

Vaidya, A.R., Sefranek, M., & Fellows, L.K. (2018) Ventromedial frontal lobe damage alters how specific attributes are weighed in subjective valuationCereb Cortex, 28(11):3857-3867.

 

2017

Yuen, T., Brouillette, M.J., Fellows, L.K., Ellis, R.J., Letendre, S., Heaton, R., Mayo, N.; CHARTER group. (2017) Personalized risk index for neurocognitive decline among people with well-controlled HIV infectionJ Acquir Immnue Defic Syndr, 76(1):48-54.

Simioni, A.C., Dagher, A., & Fellows, L.K. (2017) Effects of levodopa on corticostriatal circuits supporting working memory in Parkinson's diseaseCortex, 93:193-205.

Noonan, M.P., Chau, B.K.H., Rushworth, M.F.S., & Fellows, L.K. (2017) Contrasting effects of medial and lateral orbitofrontal cortez lesions on credit assignment and decision-making in humansJ Neurosci, 37(29):7023-7035. doi: 10.1523.

Fernandez-Cruz, A.L., & Fellows, L.K. (2017) The electrophysiology of neuroHIV: A systematic review of EEG and MEG studies in people with HIV infection since the advent of highly-active antiretroviral therapyClin Neurophysiol, 128(6):965-976. doi: 10.1016

Fellows, L.K. (2017) The neuroscience of human decision-making through the lens of learning and memory, Curr Top Behav Neurosci. doi: 10.1007/7854_2016_468.

Sanford, R., Fernandez Cruz, A.L., Scott, S.C., Mayo, N.E., Fellows, L.K., Ances, B., & Collins, D.L. (2017) Regionally specific brain volumetric and cortical thickness changes in HIV-infected patients in the HAART era, J Acquir Immune Defic Syndr. doi: 10.1097/QAI.0000000000001294.

 

2016

Peters, S.L., Fellows, L.K., & Sheldon, S. (2016) The ventromedial frontal lobe contributes to forming effective solutions to real-world problemsJ Cogn Neurosci. doi:10.1162/jocn_a_01088

Delgado, M.R., Beer, J.S., Fellows, L.K., Huettel, S.A., Platt, M.L., Quirk, G.J., & Schiller, D. (2016) Viewpoints: Dialogues on the functional role of the ventromedial prefrontal cortex, Nat Neurosci, 19(12):1545-1552. doi: 10.1038/nn.4438.

Vaidya A.R. & Fellows L.K. Necessary contributions of human frontal lobe sub-regions to reward learning in a dynamic, multidimensional environment. PDF icon supplementary_table.pdfFile multidimrl_fulldata.csv

Mayo, N.E., Brouillette, M.J., Fellows, L.K. & Positive Brain Health Now Investigators. (2016) Understanding and optimizing brain health in HIV now: protocol for a longitudinal cohort study with multiple randomized controlled trials, BMC Neurol,14;16(1):8. doi: 10.1186/s12883-016-0527-1.

Brouillette, MJ., Yuen T., Fellows, L.K., Cysique, L.A., Heaton, R.K., & Mayo, N.E. (2016) Identifying neurocognitive decline at 36 months among HIV-positive participants in the CHARTER cohort using group-based trajectory analysisPLoS One, 11(5). doi: 10.1371

Krastev, S., McGuire, J.T., McNeney, D., Kable, J.W., Stolle, D., Gidengil, E., & Fellows, L.K. (2016) Do Political and Economic Choices Rely on Common Neural Substrates? A Systematic Review of the Emerging Neuropolitics Literature, Front Psychol, 25;7:264. doi: 10.3389/fpsyg.2016.00264

 

2015

Simioni, A.C., Dagher, A. & Fellows, L.K. (2015) Compensatory striatal-cerebellar connectivity in mild-moderate Parkinson's disease, NeuroImage Clin, 10:54-62. doi: 10.1016/j.nicl.2015.11.005.
 
Vaidya, A.R. & Fellows, L.K. (2015) Testing necessary regional frontal contributions to value assessment and fixation-based updating, Nat Commun, 6:10120. doi: 10.1038/ncomms10120.
 
Vainik, U., Dubé, L., Lu, J. & Fellows, L.K. (2015) Personality and Situation Predictors of Consistent Eating Patterns, PLoS One, 10(12)e0144134. doi: 10.1371/journal.pone.0144134.
 
Brouillette, M.J., Fellows, L.K., Palladini, L., Finch, L., Thomas, R., & Mayo, N.E. (2015) Quantifying cognition at the bedside: a novel approach combining cognitive symptoms and signs in HIV. BMC Neurol, 15(1):224. doi: 10.1186/s12883-015-0483-1.
 
Vaidya, A.R., & Fellows, L.K. (2015) Ventromedial frontal cortex is critical for guiding attention to reward-predictive visual features in humans. J. Neurosci, 35(37):12813-23. doi: 10.1523/JNEUROSCI.1607-15.2015.
 
Xia, C., Stolle, D., Gidengil, E., & Fellows, L.K. (2015). Lateral orbitofrontal cortex links multi-attribute social impressions to political choices. J. Neurosci, 35:8507-14.
 
Vainik, U., Neseliler, S., Konstabel, K., Fellows, L.K. & Dagher, A. (2015). Eating traits questionnaires as a continuum of a single concept. Uncontrolled eating. Appetite, 90:229-39. doi: 10.1016/j.appet.2015.03.004.
 
Cox, S.M., Frank, M.J., Larcher, K., Fellows, L.K., Clark, C.A., Leyton,. M. & Dagher, A. (2015). Striatal D1 and D2 signaling differentially predict learning from positive and negative outcomes. Neuroimage, 109:95-101. doi: 10.1016/j.neuroimage.2014.12.070.
 
Hochman, E.Y., Wang, S., Milner, T.E. & Fellows, L.K. (2015). Double dissociation of error inhibition and correction deficits after basal ganglia or dorsomedial frontal damage in humans. Neuropsychologia, 69:130-9. doi: 10.1016/j.neuropsychologia.2015.01.023.
 

2014

Tang, D.W., Fellows, L.K., & Dagher, A. (2014). Behavioral and neural valuation of foods is driven by implicit knowledge or caloric content. Psychological Science, pii: 0956797614552081.
 
Brouillette, M.J., Mayo, N., Fellows, L.K., Lebedeva, E., Higgins, J., Overton, E.T., Ances, B.M. & Koski, L. (2014). A better screening tool for HIV-associated neurocognitive disorders: is it what clinicians need? AIDS, PMID:
25291105.
 
Geddes, M.R., Tsuchida, A., Ashley, V., Swick, D. & Fellows, L.K. (2014). Material-specific interference control is dissociable and lateralized in human prefrontal cortex. Neuropsychologia, doi: 10.1016/j.neuropsychologia.2014.09.024.
 
Vaidya, A.R., Jin C., & Fellows, L.K. (2014). Eye spy: The predictive value of fixation patterns in detecting subtle and extreme emotions from faces. Cognition, 133(2), 443-456. doi: 10.1016/j.cognition.2014.07.004
 
Hochman, E.Y., Vaidya, A.R., & Fellows, L.K. (2014). Evidence for a role for the dorsal anterior cingulate cortex in disengaging from an incorrect action. PLoS One, 9(6):e101126. doi:10.1371/journal.pone.0101126.

 

2013

Fellows, L. K. (2013). Decision-making: Executive functions meet motivation. In D. T. Stuss & R. Knight (Eds.), Principles of frontal lobe function (2nd ed.). Oxford University Press.

Fellows, L. K. (2013). Lesion studies in affective neuroscience. In J. Armony & P. Villeumier (Eds.), The Cambridge handbook of human affective neuroscience. Cambridge University Press.

Vainik, U., Dagher, A., Dubé, L., & Fellows, L. K. (2013). Neurobehavioural correlates of BMI and eating behaviours in adults: A systematic review. Neuroscience & Biobehavioral Reviews, 37(3), 279–299. doi:10.1016/j.neubiorev.2012.11.008

 

2012

Doucerain, M., & Fellows, L. K. (2012). Eating right: Linking food-related decision-making concepts from neuroscience, psychology, and education. Mind, Brain, and Education, 6(4), 206–219. doi:10.1111/j.1751-228X.2012.01159.x

Fellows, L. K. (2012). Current concepts in decision-making research from bench to bedside. Journal of the International Neuropsychological Society, 18(06), 937–941. doi:10.1017/S1355617712001294

Fellows, L. K. (2012). Group studies in experimental neuropsychology. In H. Cooper, P. M. Camic, D. L. Long, A. T. Panter, D. Rindskopf, & K. J. Sher (Eds.), APA handbook of research methods in psychology, Vol 2: Research designs: Quantitative, qualitative, neuropsychological, and biological (pp. 647–659). Washington,  DC,  US: American Psychological Association.

Hammond, R. A., Ornstein, J. T., Fellows, L. K., Dubé, L., Levitan, R., & Dagher, A. (2012). A model of food reward learning with dynamic reward exposure. Frontiers in Computational Neuroscience, 6, 82. doi:10.3389/fncom.2012.00082

Henri-Bhargava, A., Simioni, A., & Fellows, L. K. (2012). Ventromedial frontal lobe damage disrupts the accuracy, but not the speed, of value-based preference judgments. Neuropsychologia, 50(7), 1536–1542. doi:10.1016/j.neuropsychologia.2012.03.006

Simioni, A. C., Dagher, A., & Fellows, L. K. (2012). Dissecting the effects of disease and treatment on impulsivity in Parkinson’s disease. Journal of the International Neuropsychological Society, 18(06), 942–951. doi:10.1017/S135561771200094X

Tang, D. W., Fellows, L. K., Small, D. M., & Dagher, A. (2012). Food and drug cues activate similar brain regions: A meta-analysis of functional MRI studies. Physiology & Behavior, 106(3), 317–324. doi:10.1016/j.physbeh.2012.03.009

Tang, D. W., Hello, B., Mroziewicz, M., Fellows, L. K., Tyndale, R. F., & Dagher, A. (2012). Genetic variation in CYP2A6 predicts neural reactivity to smoking cues as measured using fMRI. NeuroImage, 60(4), 2136–2143. doi:10.1016/j.neuroimage.2012.01.119

Tsuchida, A., & Fellows, L. K. (2012). Are you upset? Distinct roles for orbitofrontal and lateral prefrontal cortex in detecting and distinguishing facial expressions of emotion. Cerebral Cortex. doi:10.1093/cercor/bhr370

Tsuchida, A., & Fellows, L. K. (2012). Are core component processes of executive function dissociable within the frontal lobes? Evidence from humans with focal prefrontal damage. Cortex. doi:10.1016/j.cortex.2012.10.014

 

2011

Camille, N., Griffiths, C. A., Vo, K., Fellows, L. K., & Kable, J. W. (2011). Ventromedial frontal lobe damage disrupts value maximization in humans. The Journal of Neuroscience, 31(20), 7527–7532. doi:10.1523/JNEUROSCI.6527-10.2011

Camille, N., Tsuchida, A., & Fellows, L. K. (2011). Double dissociation of stimulus-value and action-value learning in humans with orbitofrontal or anterior cingulate cortex damage. The Journal of Neuroscience, 31(42), 15048–15052. doi:10.1523/JNEUROSCI.3164-11.2011

Fellows, L. K. (2011). Orbitofrontal contributions to value-based decision making: Evidence from humans with frontal lobe damage. Annals of the New York Academy of Sciences, 1239, 51–58. doi:10.1111/j.1749-6632.2011.06229.x

Fellows, L. K. (2011). The neurology of value. In J. A. J. A. Gottfried (Ed.), Neurobiology of sensation and reward, Frontiers in Neuroscience. Boca Raton (FL): CRC Press.

Gillihan, S. J., Xia, C., Padon, A. A., Heberlein, A. S., Farah, M. J., & Fellows, L. K. (2011). Contrasting roles for lateral and ventromedial prefrontal cortex in transient and dispositional affective experience. Social Cognitive and Affective Neuroscience, 6(1), 128–137. doi:10.1093/scan/nsq026

Koski, L., Brouillette, M.-J., Lalonde, R., Hello, B., Wong, E., Tsuchida, A., & Fellows, L. K. (2011). Computerized testing augments pencil-and-paper tasks in measuring HIV-associated mild cognitive impairment. HIV Medicine, 12(8), 472–480. doi:10.1111/j.1468-1293.2010.00910.x

Venugopalan, V. V., Casey, K. F., O’Hara, C., O’Loughlin, J., Benkelfat, C., Fellows, L. K., & Leyton, M. (2011). Acute phenylalanine/tyrosine depletion reduces motivation to smoke cigarettes across stages of addiction. Neuropsychopharmacology, 36(12), 2469–2476. doi:10.1038/npp.2011.135

 

2010

Fellows, L. K. (2010). Damaged self, damaged control: A component process analysis of the effects of frontal lobe damage on human decision making. In R. Hassin, K. Ochsner, & Y. Trope (Eds.), Self Control in Society, Mind, and Brain (pp. 27–38). Oxford University Press.

Tsuchida, A., Doll, B. B., & Fellows, L. K. (2010). Beyond reversal: A critical role for human orbitofrontal cortex in flexible learning from probabilistic feedback. The Journal of Neuroscience, 30(50), 16868–16875. doi:10.1523/JNEUROSCI.1958-10.2010

 

2009

Mayo, N. E., Fellows, L. K., Scott, S. C., Cameron, J., & Wood-Dauphinee, S. (2009). A longitudinal view of apathy and its impact after stroke. Stroke, 40(10), 3299–3307. doi:10.1161/STROKEAHA.109.554410

Tsuchida, A., & Fellows, L. K. (2009). Lesion evidence that two distinct regions within prefrontal cortex are critical for n-back performance in humans. Journal of Cognitive Neuroscience, 21(12), 2263–2275. doi:10.1162/jocn.2008.21172

 

2008

Dubé, L., Bechara, A., Böckenholt, U., Ansari, A., Dagher, A., Daniel, M., DeSarbo, W. S., et al. (2008). Towards a brain-to-society systems model of individual choice. Marketing Letters, 19(3-4), 323–336. doi:10.1007/s11002-008-9057-y

Fellows, L. K., Bergman, H., Wolfson, C., & Chertkow, H. (2008). Can clinical data predict progression to dementia in amnestic mild cognitive impairment? The Canadian Journal of Neurological Sciences, 35(3), 314–322.

Fellows, L. K., Stark, M., Berg, A., & Chatterjee, A. (2008). Patient registries in cognitive neuroscience research: Advantages, challenges, and practical advice. Journal of Cognitive Neuroscience, 20(6), 1107–1113. doi:10.1162/jocn.2008.20065

Heberlein, A. S., Padon, A. A., Gillihan, S. J., Farah, M. J., & Fellows, L. K. (2008). Ventromedial frontal lobe plays a critical role in facial emotion recognition. Journal of Cognitive Neuroscience, 20(4), 721–733. doi:10.1162/jocn.2008.20049

Modirrousta, M., & Fellows, L. K. (2008). Medial prefrontal cortex plays a critical and selective role in “feeling of knowing” meta-memory judgments. Neuropsychologia, 46(12), 2958–2965. doi:10.1016/j.neuropsychologia.2008.06.011

Modirrousta, M., & Fellows, L. K. (2008). Dorsal medial prefrontal cortex plays a necessary role in rapid error prediction in humans. The Journal of Neuroscience, 28(51), 14000–14005. doi:10.1523/JNEUROSCI.4450-08.2008

Wheeler, E. Z., & Fellows, L. K. (2008). The human ventromedial frontal lobe is critical for learning from negative feedback. Brain, 131(5), 1323–1331. doi:10.1093/brain/awn041

 

2007

Fellows, L. K. (2007). The role of orbitofrontal cortex in decision making. Annals of the New York Academy of Sciences, 1121(1), 421–430. doi:10.1196/annals.1401.023

Fellows, L. K. (2007). Advances in understanding ventromedial prefrontal function: The accountant joins the executive. Neurology, 68(13), 991–995. doi:10.1212/01.wnl.0000257835.46290.57

Fellows, L. K., & Farah, M. J. (2007). The role of ventromedial prefrontal cortex in decision making: Judgment under uncertainty or judgment per se? Cerebral Cortex, 17(11), 2669–2674.

 

2006

Fellows, L. K. (2006). Deciding how to decide: Ventromedial frontal lobe damage affects information acquisition in multi-attribute decision making. Brain, 129(4), 944–952. doi:10.1093/brain/awl017

 

2005

Fellows, L. K., & Farah, M. J. (2005). Dissociable elements of human foresight: A role for the ventromedial frontal lobes in framing the future, but not in discounting future rewards. Neuropsychologia, 43(8), 1214–1221.

Fellows, L. K., & Farah, M. J. (2005). Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans. Cerebral Cortex, 15(1), 58–63. doi:10.1093/cercor/bhh108

Fellows, L. K., & Farah, M. J. (2005). Is anterior cingulate cortex necessary for cognitive control? Brain, 128(4), 788–796. doi:10.1093/brain/awh405

Fellows, L. K., Heberlein, A. S., Morales, D. A., Shivde, G., Waller, S., & Wu, D. H. (2005). Method matters: An empirical study of impact in cognitive neuroscience. Journal of Cognitive Neuroscience, 17(6), 850–858. doi:10.1162/0898929054021139

 

2004

Fellows, L. K. (2004). The cognitive neuroscience of human decision making: A review and conceptual framework. Behavioral and Cognitive Neuroscience Reviews, 3(3), 159–172. doi:10.1177/1534582304273251

 

2003

Fellows, L. K., & Farah, M. J. (2003). Ventromedial frontal cortex mediates affective shifting in humans: Evidence from a reversal learning paradigm. Brain, 126(8), 1830–1837. doi:10.1093/brain/awg180

Fellows, L. K., Foster, B. J., & Chalk, C. H. (2003). Clinical significance of complex repetitive discharges: A case-control study. Muscle & Nerve, 28(4), 504–507. doi:10.1002/mus.10425

 

1999 and earlier

Fellows, L. K. (1999). Letters to the editor-in Re: Fellows, LK, competency and onsent in dementia-reply. Journal of the American Geriatrics Society, 47(3), 377–377.

Fellows, L. K. (1998). Competency and consent in dementia. Journal of the American Geriatrics Society, 46(7), 922–926.

Fellows, L. K., Boivin, M., & Kapusta, M. (1996). Pasteurella multocida arthritis of the shoulder associated with postsurgical lymphedema. The Journal of Rheumatology, 23(10), 1824–1825.

Fellows, L. K., & Boutelle, M. G. (1993). Rapid changes in extracellular glucose levels and blood flow in the striatum of the freely moving rat. Brain Research, 604(1–2), 225–231. doi:10.1016/0006-8993(93)90373-U

Fellows, L. K., Boutelle, M. G., & Fillenz, M. (1993). ATP-sensitive potassium channels and local energy demands in the rat hippocampus: an in vivo study. Journal of Neurochemistry, 61(3), 949–954.

Fellows, L. K., Boutelle, M. G., & Fillenz, M. (1993). Physiological stimulation increases nonoxidative glucose metabolism in the brain of the freely moving rat. Journal of Neurochemistry, 60(4), 1258–1263. doi:10.1111/j.1471-4159.1993.tb03285.x

Boutelle, M. G., Fellows, L. K., & Cook, C. (1992). Enzyme packed bed system for the on-line measurement of glucose, glutamate, and lactate in brain microdialyzate. Analytical Chemistry, 64(17), 1790–1794. doi:10.1021/ac00041a010

Fellows, L. K. (1992). In vivo monitoring of cerebral energy metabolism and blood flow (PhD thesis). Oxford University, Oxford, UK.

Fellows, L. K., Boutelle, M. G., & Fillenz, M. (1992). Extracellular brain glucose levels reflect local neuronal activity: A microdialysis study in awake, freely moving rats. Journal of Neurochemistry, 59(6), 2141–2147. doi:10.1111/j.1471-4159.1992.tb10105.x

 

 

 

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