A new McGill University-led study suggests that disrupting the body’s internal clock during adolescence can alter how the brain responds to an in-utero risk factor linked to certain brain disorders.

Previous research has shown that a mother’s infection during pregnancy, such as the flu, can increase a child’s risk of developing conditions like schizophrenia and autism spectrum disorders later in life. Irregular sleep patterns – often a sign of circadian rhythm disruption – are also associated with these conditions.

Classified as: Department of Psychiatry, Douglas Research Centre, Nicolas Cermakian, brain disorders, circadian disruption
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Published on: 17 Jun 2025

 

A discovery by McGill-affiliated researchers could lead to more effective treatment of malaria and other parasitic diseases.

When mice are infected in the middle of the night with the parasites causing cerebral malaria, the symptoms of the disease are less severe than for those inflected during the day, and the spread of the parasites within the hosts is more limited, research teams from McGill University, the Douglas Research Centre and the Research Institute of the McGill University Health Centre have discovered.

Classified as: McGill Department of Psychiatry, Douglas Research Centre, McGill University Health Centre (RI-MUHC), Malaria, Nicolas Cermakian
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Published on: 19 Aug 2024

Does the time of day matter when our body is infected by a parasite? According to new research from McGill University, it matters a great deal.

Classified as: leishmania, leishmaniasis, Nicolas Cermakian, Martin Olivier, circadian clock, biological clock, health and lifestyle
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Published on: 8 Sep 2017

Does the biological clock in cancer cells influence tumour growth? Yes, according to a study conducted by Nicolas Cermakian, a professor in McGill University’s Department of Psychiatry.

Published in the journal BMC Biology, these results show for the first time that directly targeting the biological clock in a cancerous tumour has an impact on its development.

Classified as: science, Cancer, cancer cells, health and lifestyle, Nicolas Cermakian, McGill Department of Psychiatry, biological clock
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Published on: 16 Feb 2017

McGill Newsroom

Study reveals the impact of night work

You cross paths with him at the break of dawn in the corridors of the Metro. He looks bleary-eyed and pallid. This worker’s night shift just ended. His body clocks are out of sync with one another, and, imperceptibly, they’re also out of sync with his environment. In the long run, this night owl could be at greater risk of developing cardiovascular, autoimmune diseases or certain types of cancer.

Classified as: Cancer, immune system, Douglas Mental Health University Institute, shift workers, body clock, internal clock, clock, Marc Cuesta, Nicolas Cermakian, Diane B. Biovin, Journal of Immunology
Published on: 14 Jun 2016
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