Medication Trial – Do Anti-depressant medications improve outcomes in the treatment of Alcoholism?
This study examined the effects of an anti-depressant medication Citalopram in depressed and non-depressed alcoholics entering addiction treatment. Following an extensive baseline assessment, including an evaluation of depression status, and collection of blood samples for the determination of serotonin (5HT) parameters (5HT transporter polymorphism), patients were randomly assigned to receive placebo or citalopram (40 mg) in conjunction with a 12-week course of standard addiction treatment. Outcome is being examined in relation to both clinical variables (e.g. family history) and biological variables (e.g. 5HT uptake, genotypes) at intake.
- Early recovery from alcohol dependence: Factors that promote or impede abstinence. Journal of Substance Abuse Treatment, Janvier 2010 (Volume 38, pages 42 à 50), en anglais seulement.
- Personality disorders among alcoholic outpatients: Prevalence and course in treatment. Canadian Journal of Psychiatry, Février 2010, en anglais seulement.