Aminoglycoside 3'-O-phosphotransferase

Molecular surface of APH(3')-IIIa coloured based on electrostatic potential (blue = positive, red = negative) with Kanamycin (red sticks) and Neomycin (blue sticks)

Aminoglycoside 3'-O-phosphotransferase

ADP is used by the bacterial antibitiotic resistance enzyme APH(3’)-IIIa to detoxify aminoglycoside antibiotics. The fish-net surrounding the molecules is a representation of the experimentally...

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