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Tim Geary - Publications

Geary, TG, Chibale, K, Abegaz, B, Andrae-Marobela, K and Ubalijoro, E (2012)
A new approach for anthelmintic discovery for humans. Trends in parasitology
 Nwaka, S, Besson, D, Ramirez, B, et al (2011)
Integrated dataset of screening hits against multiple neglected disease pathogens. PLoS neglected tropical diseases 5 e1412.
 Geary, TG, Bourguinat, C and Prichard, RK (2011)
Evidence for macrocyclic lactone anthelmintic resistance in Dirofilaria immitis. Topics in companion animal medicine 26 186-92.
 Geary, TG and Moreno, Y (2011)
Macrocyclic Lactone Anthelmintics: Spectrum Of Activity And Mechanism Of Action. Current pharmaceutical biotechnology
 Moreno, Y, Gros, PP, Tam, M, Segura, M, Valanparambil, R, Geary, TG and Stevenson, MM (2011)
Proteomic analysis of excretory-secretory products of Heligmosomoides polygyrus assessed with next-generation sequencing transcriptomic information. PLoS neglected tropical diseases 5 e1370.
 Geary, TG and Mackenzie, CD (2011)
Progress and challenges in the discovery of macrofilaricidal drugs. Expert review of anti-infective therapy 9 681-95.
 Mackenzie, CD and Geary, TG (2011)
Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs. Expert review of anti-infective therapy 9 497-501.
 Bourguinat, C, Keller, K, Bhan, A, Peregrine, A, Geary, T and Prichard, R (2011)
Macrocyclic lactone resistance in Dirofilaria immitis. Veterinary parasitology 181 388-92.
 Bourguinat, C, Keller, K, Prichard, RK and Geary, TG (2011)
Genetic polymorphism in Dirofilaria immitis. Veterinary parasitology 176 368-73.
 Bourguinat, C, Keller, K, Blagburn, B, Schenker, R, Geary, TG and Prichard, RK (2011)
Correlation between loss of efficacy of macrocyclic lactone heartworm anthelmintics and P-glycoprotein genotype. Veterinary parasitology 176 374-81.
 Ruiz-Lancheros, E, Viau, C, Walter, TN, Francis, A and Geary, TG (2011)
Activity of novel nicotinic anthelmintics in cut preparations of Caenorhabditis elegans. International journal for parasitology 41 455-61.
Moreno, Y., Nabhan, J. F., Solomon, J., Mackenzie, C. D., Geary, T. G. (2010)
Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi. Proc Natl Acad Sci U S A 107 20120-20125.
Mackenzie, C. D., Huntington, M. K., Wanji, S., Lovato, R. V., Eversole, R. R., Geary, T. G. (2010)
The association of adult Onchocerca volvulus with lymphatic vessels. The Journal of parasitology 96 219-221.
Geary, T. G., Woo, K., McCarthy, J. S., Mackenzie, C. D., Horton, J., Prichard, R. K., de Silva, N. R., Olliaro, P. L., Lazdins-Helds, J. K., Engels, D. A., Bundy, D. A. (2010)
Unresolved issues in anthelmintic pharmacology for helminthiases of humans. Int J Parasitol 40 1-13.
Geary, T. G., Maule, A. G. (2010)
Neuropeptide systems as targets for parasite and pest control. Preface. Advances in experimental medicine and biology 692 v-vi.
Geary, T. G. (2010)
Nonpeptide ligands for peptidergic G protein-coupled receptors. Adv Exp Med Biol 692 10-26.
Bourguinat, C., Kamgno, J., Boussinesq, M., Mackenzie, C. D., Prichard, R. K., Geary, T. G. (2010)
Analysis of the mdr-1 gene in patients co-infected with Onchocerca volvulus and Loa loa who experienced a post-ivermectin serious adverse event. Am J Trop Med Hyg 83 28-32.
Schwab, A. E., Geary, T. G., Baillargeon, P., Schwab, A. J., Fecteau, G. (2009)
Association of BoLA DRB3 and DQA1 alleles with susceptibility to Neospora caninum and reproductive outcome in Quebec Holstein cattle. Veterinary Parasitology 165 136-140.
Prichard, R. K., Geary, T. G. (2008)
Drug discovery: fresh hope to can the worms. Nature 452 157-158.
Moreno, Y., Geary, T. G. (2008)
Stage- and gender-specific proteomic analysis of Brugia malayi excretory-secretory products. PLoS Negl Trop Dis 2 e326.
Kubiak, T. M., Larsen, M. J., Bowman, J. W., Geary, T. G., Lowery, D. E. (2008)
FMRFamide-like peptides encoded on the flp-18 precursor gene activate two isoforms of the orphan Caenorhabditis elegans G-protein-coupled receptor Y58G8A.4 heterologously expressed in mammalian cells. Biopolymers 90 339-348.
Prichard, R. K., von Samson-Himmelstjerna, G., Blackhall, W. J., Geary, T. G. (2007)
Foreword: towards markers for anthelmintic resistance in helminths of importance in animal and human health. Parasitology 134 1073-1076.
Omar, H. H., Humphries, J. E., Larsen, M. J., Kubiak, T. M., Geary, T. G., Maule, A. G., Kimber, M. J., Day, T. A. (2007)
Identification of a platyhelminth neuropeptide receptor. International Journal for Parasitology 37 725-733.
McVeigh, P., Leech, S., Marks, N. J., Geary, T. G., Maule, A. G. (2006)
Gene expression and pharmacology of nematode NLP-12 neuropeptides. International Journal for Parasitology 36 633-640.
McVeigh, P., Geary, T. G., Marks, N. J., Maule, A. G. (2006)
The FLP-side of nematodes. Trends in Parasitology 22 385-396.
Mousley, A., Moffett, C. L., Duve, H., Thorpe, A., Halton, D. W., Geary, T. G., Thompson, D. P., Maule, A. G., Marks, N. J. (2005)
Expression and bioactivity of allatostatin-like neuropeptides in helminths. International Journal for Parasitology 35 1557-1567.
McVeigh, P., Leech, S., Mair, G. R., Marks, N. J., Geary, T. G., Maule, A. G. (2005)
Analysis of FMRFamide-like peptide (FLP) diversity in phylum Nematoda. International Journal for Parasitology 35 1043-1060.
Geary, T. G., Kubiak, T. M. (2005)
Neuropeptide G-protein-coupled receptors, their cognate ligands and behavior in Caenorhabditis elegans. Trends in pharmacological sciences 26 56-58.
Geary, T. G. (2005)
Ivermectin 20 years on: maturation of a wonder drug. Trends in Parasitology 21 530-532.
Mousley, A., Marks, N. J., Halton, D. W., Geary, T. G., Thompson, D. P., Maule, A. G. (2004)
Arthropod FMRFamide-related peptides modulate muscle activity in helminths. International Journal for Parasitology 34 755-768.
Johnson, S. S., Coscarelli, E. M., Davis, J. P., Zaya, R. M., Day, J. S., Barsuhn, C. L., Martin, R. A., Vidmar, T. J., Lee, B. H., Conder, G. A., Geary, T. G., Ho, N. F., Thompson, D. P. (2004)
Interrelationships among physicochemical properties, absorption and anthelmintic activities of 2-desoxoparaherquamide and selected analogs. Journal of Veterinary Pharmacology and Therapeutics 27 169-181.
Geary, T. G., Conder, G. A., Bishop, B. (2004)
The changing landscape of antiparasitic drug discovery for veterinary medicine. Trends in Parasitology 20 449-455.
Ellerbrock, B. R., Coscarelli, E. M., Gurney, M. E., Geary, T. G. (2004)
Screening for presenilin inhibitors using the free-living nematode, Caenorhabditis elegans. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening 9 147-152.