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About the Clinical Exercise & Respiratory Physiology Laboratory (CERPL)

Research in the CERPL focuses primarily on the mechanisms, measurement and management of breathlessness and physical activity-limitation in health, variants of health (e.g., elderly, obesity) and in patients with chronic cardiorespiratory disease, specifically chronic obstructive pulmonary disease.

We employ an integrative physiological approach and a comprehensive suite of human physiological measurement techniques to better understand how physiological and pathophysiological abnormalities of neural respiratory drive, dynamic respiratory mechanical/muscular function, cardiometabolic and peripheral locomotor muscle function, ventilatory control, acid-base balance and their complex interaction(s) contribute to the origin of breathlessness and physical activity-limitation in these populations.  

This information, in turn, helps to identify more effective treatments aimed at relieving exertional symptoms, and improving functional capacity and health-related quality-of-life in various patient populations.