Visiting colleagues at Purdue University

Hani, Neda, Luc, Siavash and Hossein

Brainstorming session over Persian dinner

Mongeau Research Group members with visiting colleague Nicole Li

Former grad students

Scott Thompson (now at Bringham Young University), colleague Byron Erath, Matias Zanartu (now at Universidad Técnica Federico Santa María), Luc, Zhaoyan Zhang (now at UCLA), and Douglas Cook (now at New York University Abu Dhabi)

Principal Investigator

Photograph of Lab Director Luc Mongeau

luc.mongeau [at] (Professor Luc Mongeau)

Research Interests: Vocal fold tissue engineering, Voice production, aerodynamic noise in vehicles, thermoacoustic refrigeration, turbomachinery noise, control of flow-induced sound and vibrations. 

More Information

Lab Manager

annie.douillette [at] (Annie Hélène Douillette)

I have a Biotechnology and Pharmaceutical Sciences background. I'm currently working as both the lab manager and a research assistant in Proffessor Mongeau's group. As such, I do some administrative duties, I follow up on good laboratory practices, I provide training and finally help students with the biological aspects of their projects.  I also try to develop new techniques and project ideas. My purpose is to bring some continuities in the laboratory.


PhD Students

neda.latifialavijeh [at] (Neda Latifi) 

Research Interests: My interests lie in the development and verification of a bio-mimetic bioreactor for vocal fold tissue engineering andmechanobiology investigations. The most serious disease conditions affecting voice are those in which part of the soft and pliable mucosa is lost or replaced by stiff fibrous tissue. In such cases, injectable biomaterials are used to regenerate functional vocal fold tissue. However, the long-term functional outcome of the current biomaterials is unpredictable. Human phonation involves complex biomechanical stimulation. However, little experimental data exists in the literature pointing the influence of the phonation-induced mechanical stimulation on the functional behavior of human vocal fold fibroblasts (HVFFs). My main goal is to develop a phono-mimetic platform: to investigate how HVFFs respond to phonation-induced mechanical stimulation (Mechanical Microenvironment) in terms of the production and remodeling of extracellular matrix proteins; and to investigate the long-term effects of injectable biomaterials for vocal fold tissue engineering in a phono-mimetic environment prior to performing animal and clinical studies. This novel bioreactor facilitates the biomaterial optimization for vocal fold tissue engineering and reduces the number of animals sacrificed to obtain functional injectable biomaterials; and ultimately to engineer neo-vocal fold tissue in the laboratory for the partial or full-replacement of the damaged human vocal folds.

Thesis: Investigations on the vocal fold tissue engineering and mechanobiology using a bio-mimetic bioreactor.

zhengdong.lei [at] (Zhengdong Lei)

Research Interests: My research mainly focuses on human vocal system (subglottal, glottis and vocal tract) modeling and simulation, acoustic signal processing and analysis. I am also trying to find a non-invasive means to acquire human voice data for daily dose by using a Glottal Notch Accelerometer (GNA) attached on neck surface.

Thesis: "Voice detection and classification by utilizing a neck-surface-attached accelerometer".

mostafa.najafiyazdi [at] (Mostafa Najafiyazdi)

Research Interests: Large-Eddy Simulations (LES), explicit filtering, approximate deconvolution models, jet noise simulation, mesh adaptation

Research Description: My research is focused on extending the application of explicit spatial filtering schemes to unstructured Large-Eddy Simulations (LES) using Approximate Deconvolution Methods. One major challenge is the definition of a well-defined spatial filter which is not only a-stable, but also goes to zero at the grid cut-off wavenumber at any point in the mesh. Extension of such filter for bounded geometries is another difficulty which not only should maintain the level of accuracy but also should have minimum possible commutation error with numerical differentiation operators. The goal of this research is to provide unstructured flow solvers with a suitable means for high-order LES capabilities to capture jet noise simulations.

guangyu.bao [at] (Guangyu Bao) 

Thesis: Phonomimetic Functionalization of Multicellular and Multilayered Vocal Fold Grafts

hossein.ravanbakhsh [at] (Hossein Ravanbakhsh) ​​

Thesis: Mechanobiological Behavior of Fibrous Composite Hydrogels for Vocal Fold Tissue Engineering

rayane.aitoubahou [at] (Rayane Ait Oubahou) ​​​

Thesis: Lobed Mixers: An Investigation of the Near Flow-Field and Associated Far-Field Noise Radiation using the Lattice Boltzmann Method

mehdi.shamshiri [at] (Mehdi Shamshiri) ​​​

Thesis: Modeling and Simulation of Targeted Drug Delivery for Head and Neck Cancer

Master's Students

marius.muller [at] (Marius Muller) 

Thesis: Rayleigh Wave Method for Measuring the Frequency-dependent Shear Modulus of Soft Biomaterials

pooya.saberi [at] (Pooya Saberi) 

Thesis: Effect of Tissue Material Properties on Fluid-Structure Models of Human Phonation

alicia.reyes [at] (Alicia Reyes) 

Thesis: Artificial Cells for the Regeneration of Vocal Fold Lamina Propria

haoqing.liu [at] (Haoqing Liu) 

Project: Application of Functionalized Carbon Nanotubes in Human Vocal Fold Treatment

Undergraduate Students

rohit.gopinath [at] (Rohit Gopinath)

miral.toufaili [at] (Miral Toufaili) 

maxence.coulombe [at] (Maxence Coulombe) 


Postdoctoral Fellows

meisam.asgari [at] (Meisam Asgari)

Research Interests: Mechanics of collagen; Constitutive modeling and mechanical characterization; Atomic Force Microscopy imaging and force measurements.

hossein.khadiviheris [at] (Hossein Khadivi Heris)

Research Interests: Mechanobiology; Biomaterials Engineering; Regenerative Medicine; Biomechanics.

Alireza.najafiyazdi [at] (Alireza Najafiyazdi)

Research Interests: Computational Turbulent Combustion; Computational Aeroacoustics; Large Eddy Simulation (LES).

rani.taher [at] (Rani Taher)

Research Interests: Design, optimization and performance evaluation of thermoacoustic cooling systems; heat-transfer characteristics of thermal devices using Planar Laser-Induced Fluorescence (PLIF); high-resolution velocity fields measurements using time-resolved and phase-locked Particle Image Velocimetry (PIV).

Photograph of graduate student Rani Taher


PhD Students

meisam.asgari [at] (Meisam Asgari)

Research Interests: Nonlinear elasticity, and large elastic deformation of biological soft tissues.

Thesis: "Modeling and analysis of self-assembled hierarchical nano-structures: Wormlike micelles, toroidal bundles, open lipid bilayers, and collagen fibrils".

shahin.amiri [at] (Shahin Amiri)

Photograph of graduate student Shahin Amiri


Research Interests: Thermoacoustic refrigeration and thermal design of heat exchangers.

Thesis: "Heat transfer characteristics of heat exchangers in standing wave thermoacoustic refrigeration systems".

hani.bakhshaei [at] (Hani Bakhshaee)Photograph of graduate student Hani Bakhshaei

Research Interests: Computational fluid dynamics using the Lattice Boltzmann and Finite Element models; image processing with 3D reconstruction of the larynx and vocal folds and overlapping high-speed camera images, CT scan and MRI data; high-speed imaging of porcine excised larynges and rubber models of vocal folds. 

Thesis: "Computational models of human laryngeal flows".

kaveh.habibi [at] (Kaveh Habibi)Photograph of graduate student Kaveh Habibi

Research Interests: I am working on the design of aircraft noise suppression devices by Large Eddy Simulation(LES) of turbulent flows inside the turbofan engines.

ahmad.jamal [at] (Ahmad Jamal)

Research Interests: The objectives of my research are to develop a 3-D coupled nonlinear model for an enclosed flexible cylindrical structure in axial flow, investigate the effects of confinement and eccentricity on its physical dynamics under different boundary conditions, develop a 3-D simulation model in the software ADINA, and perform confinement experiments to validate the theory.  

Thesis: "Three-Dimensional Nonlinear Cylinder Dynamics in Confined Channel Flow".

siavash.kazemirad [at] (Siavash Kazemirad)Photograph of graduate student Siavash Kazemirad

Research Interests: Wave propagation methods; vibrations and acoustics; biomechanics; mechanical behavior of biomaterials.

Thesis: "Experimental wave propagation methods for the characterization of the frequency-dependent viscoelastic properties of soft tissues and biomaterials".

hossein.khadiviheris [at] (Hossein Khadivi Heris)Photograph of graduate student Hossein Khadivi Heris

Research Interests: Naturally derived hydrogel materials can exhibit chemical, physical and biological properties similar to soft tissue. Mechanical properties play a significant role in scar formation and tissue remodeling in the mechanically oscillating vocal fold tissue. I use atomic force microscopy (AFM) as a multiscale characterization tool to assess the viscoelastic properties of vocal fold tissues and synthesized microgels and hydrogels.

Thesis: "Development and characterization of microgel-hydrogel system for voice restoration in scarred vocal fold tissue".

neda.latifialavijeh [at] (Neda Latifi)Photograph of graduate student Neda Latifi

Research Interests: Experimental and computational biomechanics with an emphasis on soft biological tissues, nonlinear finite element methods, the biomechanical characterization of soft biological tissues, and constitutive (multiscale) modeling of solids at finite strains.

amir.miriramsheh [at] (Amir K. Miri)

Photograph of graduate student Amir K. Miri

Research Interests: The mechanical characterization of biological soft tissues, multiscale modeling of soft materials involving large deformation and nonlinear laser scanning microscopy of biological tissues and biomedical materials.

Thesis: "Mechanical Characterization of Vocal Folds by a Multiscale Study".

yasser.rafat [at] (Yasser Rafat)

Research Interests: Rayleigh streaming acoustic flow interaction with streamline structures in a standing wave acoustic resonator. Employing PIV, we try to characterize the flow interactions and their effect on the performance of a thermoacoustic refrigerator.

Thesis: "Experimental study of streaming flows in acoustic standing wave tubes".

alireza.najafiyazdi [at] (Alireza Najafiyazdi)

Research Interests: Computational Turbulent Combustion; Computational Aeroacoustics; Large Eddy Simulation (LES).

By creating new models and innovative algorithms, I try to provide automobile manufacturers and aerospace industries with high-fidelity, massively parallel codes necessary for the design and multidisciplinary optimization (MDO) of more environmentally friendly products. In particular, my research involves the use of Large Eddy Simulation (LES) and hybrid Reynolds Averaged-LES for turbulent combustion and aeroacoustics.

Thesis: "Large Eddy Simulation of Sound Generation by Turbulent Reacting and Nonreacting Jet Flows".

Master's Students

vahid.noohi [at] (Vahid Noohi) 

Research Interests: Amongst diverse group of fields that mechanical engineering has to offer, I find design and manufacturing fascinating. I have always been passionate about pursuing my graduate studies in bioengineering. During my Undergraduate years I had the opportunity to study composite materials in great details. The nature of this experience has been very important in defining my Master's project in the field of bioengineering. The main goal of my research project is to introduce singular micro chitosan fibers into the glycol-chitosan hydrogel matrix in order to facilitate cell mobility and migration. This scaffold will be used for treatment of vocal cords’ scars. Wet-spinning was selected as a method of manufacturing due to its efficiency and low cost of production.

caroline.shung [at] (Caroline Shung)

Research Interests: Analysis of cellular behavior and tissue regeneration in the presence of biomimetic materials, computational modelling

Thesis: Developing an agent based model for vocal fold inflammation and wound healing.

Photograph of graduate student Daniel Armstrongdaniel.armstrong2 [at] (Daniel Armstrong)

Research Interests: Working with new CAA software in order to predict and minimize the noise emissions from flow past airframe components.

Thesis: "Numerical simulations of flows over aircraft landing gears".

Photograph of graduate student Alfred Chanalfred.chan [at] (Alfred Chan)

Research Interests: Vocal fold mechanics using laser Doppler vibrometry, experiments performed in vivo and on excised larynges.

Thesis: "Vocal Fold Vibration Measurements using Laser Doppler Vibrometry".

Photograph of graduate student Hao Gonghao.gong [at] (Hao Gong)

Research Interests: Using computational fluid dynamics to predict and minimize jet noise for the purpose of optimizing design.

Thesis: "Three-Dimensional Jet Noise Prediction Using Lattice Boltzmann Method".

marguerite.jossic [at] (Marguerite Jossic)

Undergraduate Students

merlyn.christopher [at] (Merlyn Christopher) 

ghulam.murtaza [at] (Ghulam Murtaza)

scott.park [at] (Scott Park)

Projects: Fabrication of perfusion bioreactor models, Functional analysis of rabbit vocal fold vibrations.

justin.armagnat [at] (Justin Armagnat)

Projects: Clinical measurements, LDV at glottal notch and inverse filtering for the Rothenberg mask.

christina5198 [at] (Christina Chen)

juan.henao [at] (Juan Felipe Henao)

Projects: Three-dimensional reconstruction of vocal folds using image analysis software; Finite Element Modeling of vocal folds.

madonna.ibrahim [at] (Madonna Ibrahim)

leon.johnson [at] (Leon Johnson)

Projects: Mechanical simulation of phonation; Development of synthetic vocal fold models.

Zhe.li2 [at] (Sophie Zhe Li)

Projects: Image processing with high-speed camera images; electroglottography; 3D reconstruction of the larynx and vocal folds with MRI data.

yun.li4 [at] (Yun Yvonna Li)

Project: Agent based modeling of wound healing in the vocal folds.

kelsey.mcgivern [at] (Kelsey McGivern)

Project: Mechanical simulation of phonation and development of synthetic vocal fold models.

liam.meade [at] (Liam Mead)

Project: Vocal fold bioreactor.

christina.moro [at] (Christina Moro)

Projects: Three-dimensional reconstruction of the larynx and vocal folds using high-speed Imaging, CT scans and MRI.

jasmin.wong [at] (Jasmin Wong)

Project: Immunohistochemistry on tissue slides.

chanwoo.yang [at] (Justin (Chanwoo) Yang)

Project: Biomedical Engineering and biomechanics.

ryan.tiensingyoung [at] (Ryan Tien Sing Young)

Project: Biomedical Engineering particularly biomaterials and biocompatibility.