Core research papers
Cinkornpumin JK, Kwon SY, Prandstetter AM, Maxian T, Sirois J, Goldberg J, Zhang J, Saini D, Dasgupta P, Jeyarajah MJ, Renaud SJ, Paul S, Haider S, Pastor WA. (2025) Hypoxia and loss of GCM1 expression prevent differentiation and contact inhibition in human trophoblast stem cells. Stem Cell Reports. 20:02481. Link
Hossain I, Priam P, Reynoso SC, Sahni S, Zhang XX, Côté L, Doumat J, Chik C, Fu T, Lessard JA, Pastor WA. (2024) ZIC2 and ZIC3 promote SWI/SNF recruitment to safeguard progression towards human primed pluripotency. Nature Communications. 15(1):8539. Link
Graham-Paquin A., Saini D., Sirois J., Hossain I., Katz M.S., Zhuang Q.K., Kwon S.Y., Yamanaka Y., Bourque G., Bouchard M., Pastor W.A. (2023) ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development. Nucleic Acids Research 51(14): 7314–7329. Link
Azevedo Portilho N., Saini D., Hossain I., Sirois J., Moraes C., Pastor W.A. (2021) The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells. Epigenetics & Chromatin 14(1):56. Link
Cinkornpumin J.K., Kwon S.Y., Guo Y., Hossain I., Sirois J., Russett C.S., Tseng H., Okae H., Arima T., Duchaine T.F., Liu W., Pastor W.A. (2020) Naive Human Embryonic Stem Cells Can Give Rise to Cells with a Trophoblast-like Transcriptome and Methylome. Stem Cell Reports. 15(1):198-213. Link
Collaborative research papers
Penalva YCM, Paschkowsky S, Yang J, Recinto SJ, Cinkornpumin JK, Ruelas M, Xiao B, Nitu A, Kwon SY, Wu HY, Munter HM, Michalski B, Fahnestock M, Pastor WA, Bennett DA, Munter LM. (2025) Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model. Cell Death Dis. 16(1):280. Link
Su C, Pastor WA, Emad A. (2024) Deciphering lineage-relevant gene regulatory networks during endoderm formation by InPheRNo-ChIP. Brief Bioinform. 25(6):bbae592. Link
Cai T., Cinkornpumin J.K., Yu Z., Villareal O.D., Pastor W.A., Richard S. (2021) Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects. Cell Reports. 36(2):109337. Link
Chen H., Hu B., Horth C., Bareke E., Rosenbaum P., Kwon S.Y., Sirois J., Weinberg D.N., Robison F.M., Garcia B.A., Lu C., Pastor W.A., Majewski J. (2022). H3K36 dimethylation shapes the epigenetic interaction landscape by directing repressive chromatin modifications in embryonic stem cells. Genome Research. 32(5):825-837. Link
Rahbani J.F., Scholtes C., Lagarde D.M., Hussain M.F., Roesler A., Dykstra C.B., Bunk J., Samborska B., O'Brien S.L., Tripp E., Pacis A., Angueira A.R., Johansen O.S., Cinkornpumin J., Hossain I., Lynes M.D., Zhang Y., White A.P., Pastor W.A., Chondronikola M., Sidossis L., Klein S., Kralli A., Cypess A.M., Pedersen S.B., Jessen N., Tseng Y.H., Gerhart-Hines Z., Seale P., Calebiro D., Giguère V., Kazak L. ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP. Nature Metabolism. 4(11):1459-1473. Link
Xue Y., Meehan B., Fu Z., Wang X.Q.D., Fiset P., Rieker R., Levins C., Kong T., Zhu X., Morin G., Skerritt L., Esther H., Venneti S., Martinez D., Jung S., Gonzalez A.V., Guiot M.C., Lockwood W., Spicer J., Agaimy A., Pastor W.A., Dostie J., Rak J., Foulkes W.D., Huang S. (2019) SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer. Nature Communications. 10(1): 557. Link
Review articles & book chapters
Pastor W.A., Kwon S.Y. (2022) Distinctive aspects of the placental epigenome and theories as to how they arise. Cell and Molecular Life Sciences. 79(11):569. Link
Parameshwar PK, Sagrillo-Fagundes L, Azevedo Portilho N, Pastor WA, Vaillancourt C, Moraes C. (2022) Engineered models for placental toxicology: Emerging approaches based on tissue decellularization. 112:148-159. Link
Cinkornpumin J.K., Hossain I., Pastor W.A. Mapping Chromatin Accessibility in Human Naïve Pluripotent Stem Cells Using ATAC-Seq. (2022). Methods in Molecular Biology. 2416:201-211. Link