Structure/function analysis of FOXL2 in FSH transcription - ANAT 396 Undergraduate Research Project Application Form

Supervisor's Name: Daniel Bernard

Supervisor's Email: daniel.bernard [at] mcgill.ca

Supervisor's Phone: 514-398-2525

Supervisor's Website: https://mcgill.ca/pharma/facultystaff/faculty/dan-bernard/

Supervisor's department: Pharmacology

Course number: ANAT 396 (Anatomy and Cell Biology)

Term: Fall 2014-2015

Project start date: September 2, 2014

Project end date: December 5, 2014

Project title: Structure/function analysis of FOXL2 in FSH transcription

Project description (50-100 words suggested): The student will map functional domains of FOXL2 required for its transcriptional regulation of the FSH beta subunit. Analyses will include in vitro mutagenesis, DNA sequencing, plasmid preparations, mammalian cell culture, transfection, reporter assays, western blots, immunoprecipitation, immunofluorescence.

Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.

Grading scheme (The final report must be worth at least 50% of final grade): Final grade shall be based on an evaluation of laboratory performance (40%), a final written report (50%), and an oral presentation (10%).

Project status: This project is taken. The professor has no more '396' projects this term.

Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves: Biohazardous substances; Handling chemicals.