Supervisor's Name: Dr. Craig Mandato
Supervisor's Email: craig.mandato [at] mcgill.ca
Supervisor's department: Anatomy and Cell Biology
Course number: ANAT 396 (Anatomy and Cell Biology)
Term: Fall 2013-2014
Project start date: Tuesday, September 3, 2013
Project end date: Tuesday, December 3, 2013
Project title: Effects of tensegrity on cellular wound healing in xenopus laevis oocytes
Project description (50-100 words suggested):Microassaults on Xenopus oocytes initiate cellular wound healing mechanisms, and much research has focused on detailing the biochemical events at the wound edge. Actin is transported to the wound edge via microtubules where it begins to polymerize into cables incorporating also myosin. The contractile properties of this actomyosin ring helps close the wound. The capacity of a cell to heal itself should depend on its tensegrity, so we propose to analyze the molecular components responsible for wound healing when cellular osmotic pressure is modified.
Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.
Grading scheme (The final report must be worth at least 50% of final grade): Laboratory (50%), final written report (50%)
Project status: This project is taken. The professor has no more '396' projects this term.
How students can apply: N/A; this project is filled.
Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves: Animal subjects; Using lasers.