'Effects on polymer confinement in nanocavities by varying buffer ionic strength' - PHYS 396 Undergraduate Research Project Application Form

Supervisor's Name: Walter Reisner

Supervisor's Email: reisner [at] physics.mcgill.ca

Supervisor's Phone:

Supervisor's Website:

Supervisor's department: Physics

Course number: PHYS 396 (Physics)

Term: Summer 2013

Project start date: July 6th 2013

Project end date: August 30th 2013

Project title: Effects on polymer confinement in nanocavities by varying buffer ionic strength

Project description (50-100 words suggested):Ionic environment plays a crucial role in the configuration of DNA confined in nanofluidic chip-based devices. For example, DNA extension in nanochannels increases as ionic strength is reduced. This is due to the variation of persistence length with ionic strength, and more importantly due to an increase in self-avoidance caused by reduced screening of electrostatic interactions at low ionic strength (i.e. the effective width of DNA). The main focus of this project is on single-nanocavity confinement, and how parameters such as filling, filling variance, and effective DNA width are affected by ionic environment.

Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.

Grading scheme (The final report must be worth at least 50% of final grade): Final grade shall be based on laboratory performance (50%), and a final written report (50%).

Project status: This project is taken. The professor has no more '396' projects this term.

How students can apply: N/A; this project is filled.

Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves handling chemicals.