'Effects of drugs during adolescence on dopamine innervation in the lateral habenula' - NSCI 396 Undergraduate Research Project Application Form

Supervisor's Name: Cecilia Flores

Supervisor's Email: cecilia.flores [at] mcgill.ca

Supervisor's Phone: (514)761 6131 x 2814

Supervisor's Website: http://ceciliafloreslab.com

Supervisor's department: Psychiatry

Course number: NSCI 396 (Neuroscience)

Term: Summer 2013

Project start date: Wednesday, May 6, 2013

Project end date: Friday, August 30, 2013

Project title: Effects of drugs during adolescence on dopamine innervation in the lateral habenula

Project description: Altered dopamine innervation in the lateral habenula, a brain region which exerts influence over the function of areas important for drug reward and addiction, may play a role in mediating the vulnerability to addiction noted after adolescent drug use. This project will compare the dopamine innervation of this region in mice that received drugs during adolescence and will complement behavioral data collected in these mice. The project involves stereological analysis of dopamine terminals in the lateral habenula of mice that received either a sensitizing regimen of amphetamine in early adolescence, or a control regimen of saline.

Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.

Grading scheme (The final report must be worth at least 50% of final grade): Final grade shall be based on laboratory performance as evaluated by the research supervisor (50%) and the final written research report (minimum 10 pages) graded by the supervisor and the course coordinator or the coordinator's delegate (50%).

Project status: This project is taken. The professor has no more '396' projects this term.

How students can apply: N/A; this project is filled.

Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves: Handling chemicals.