'T follicular helper cell differentiation following infection' - MIMM 397 Undergraduate Research Project Application Form

Supervisor's Name: Dr. Irah King

Supervisor's Email: irah.king [at] mcgill.ca

Supervisor's Phone: (514) 398-7325

Supervisor's Website:

Supervisor's department: Microbiology and Immunology

Course number: MIMM 397 (Immunology

Term: Summer 2013

Project start date: May 20, 2013

Project end date: August 16, 2013

Project title: T follicular helper cell differentiation following infection

Project description (50-100 words suggested): CD4+ T follicular helper (Tfh) cells play a critical role in generating protective antibody responses following infection by directing interacting with pathogen-specific B cells. Using mouse models of infection to interrogate T-dependent humoral immune responses during intestinal parasite infection, the student will not only gain experience using a number of in vitro and in vivo experimental assays to test specific hypotheses regarding Tfh cell differentiation and function, but also increase her fund of knowledge regarding general principles of cellular immunology.

Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.

Grading scheme (The final report must be worth at least 50% of final grade): Final grade shall be based on laboratory performance as evaluated by the research supervisor (50%) and the final written research report (minimum 10 pages) graded by the supervisor and the course coordinator or the coordinator's delegate (50%).

Project status: This project is taken.

How students can apply: For MIMM: After all parts of this application form are completed, and the hard copy is signed by the professor and the student, bring this application form and your unofficial transcript to Prof. Gregory Marczynski during office hours, who will review/approve as the course coordinator for MIMM 396 (Microbiology) or MIMM 397 (Immunology).

Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves: Animal subjects.