Novel functions of Spt5, a conserved transcription elongation factor - PHAR 396 Undergraduate Research Project Application Form

Supervisor's Name: Jason Tanny

Supervisor's Email: jason.tanny [at]

Supervisor's Phone:

Supervisor's Website:

Supervisor's department: Pharmacology

Course number: PHAR 396

Term: Fall 2015-2016

Project start date: Friday, September 4, 2015

Project end date: Monday, December 7, 2015

Project title: Novel functions of Spt5, a conserved transcription elongation factor

Project description (50-100 words suggested): Using the fission yeast S. pombe as a model system, genetic interactions between alleles of Spt5 and gene knockouts recovered from a genome-wide screen will be validated. The knockouts affect various aspects of chromatin structure and RNA processing. Spt5 function in these processes will be assessed using further genetic analysis and biochemical techniques such as chromatin immunoprecipitation.

Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.

Grading scheme (The final report must be worth at least 50% of final grade): Final report-50%; Performance in the lab-50%.

Project status: This project is taken; however students may contact the professor to discuss other possible '396' projects this term.

How students can apply / Next steps: Please contact course coordinator Dr. Jason Tanny (jason.tanny [at] for approval

Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves: Biohazardous substances; Handling chemicals.