Osr1 and vesico-ureteric reflux - HGEN 396 Undergraduate Research Project Application Form

Supervisor's Name: Dr. Indra R. Gupta

Supervisor's Email: indra.gupta [at] muhc.mcgill.ca

Supervisor's Phone: 514-412-4400 ext 23539

Supervisor's Website:

Supervisor's department: Human Genetics

Course number: HGEN 396 (Human Genetics)

Term: Fall 2015-2016

Project start date: Friday, September 11, 2015

Project end date: Monday, December 7, 2015

Project title: Osr1 and vesico-ureteric reflux


Project description (50-100 words suggested): Vesico-ureteric reflux is a common congenital urinary tract defect in which urine flows retrogradely from the bladder to the kidneys resulting in urine infections.  We have identified a mutation in the transcription factor Osr1 that leads to vesico-ureteric reflux in children and in mice. The student will be involved in performing an expression analysis of Osr1 in the developing mouse embyro.

Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.

Grading scheme (The final report must be worth at least 50% of final grade): Final grade will be based on an evaluation of laboratory performance-40%, written report-50%, and oral presentation-10%.

Other project information:

  • This project will involve work with mouse embryos and tissues at the Research Institute of the McGill University Health Center.
  • Interested students should contact me by email at indra.gupta [at] muhc.mcgill.ca and include an unofficial copy of their transcripts and their curriculum vitae.

Project status: This project is open to applicant.

How students can apply / Next steps: After all of the parts of this application forms are completed and the hard copy is signed by the professor and the student, bring the application form and a copy of your unofficial transcript to the Department of Human Genetics (to the attention of Dr. Patricia N. Tonin, Stewart Biology Building N5.13) during office hours.

Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves: Animal subjects; Biohazardous substances; Handling chemicals.