Supervisor's Name: James Gleason
Supervisor's Email: jim.gleason [at] mcgill.ca
Supervisor's Phone: 398-5596
Supervisor's Website: gleason-group.mcgill.ca
Supervisor's department: Chemistry
Course number: CHEM 396 (Chemistry)
Term: Winter 2013-2014
Project start date: Monday, January 6, 2014
Project end date: Friday, April 11, 2014
Project title: Organocatalytic Diels-Alder Reactions
Project description (50-100 words suggested): This project will examine the organocatalysis of Diels-Alder reactions. Specifically, prior work in this area has established that alpha,beta-unsaturated aldehydes undergo Diels-Alder cycloadditions using secondary amines as bases. However, substrates in this reaction are limited to those which lack additional alpha substituents. Our research group has identified a hydrazide catalyst that initiates Cope rearrangements with sterically hindered enals. This project will examine the extension of these hydrazide catalysts to the Diels-Alder cycloaddition.
Prerequisite: CHEM 302 + CGPA of 3.0 or higher and permission of instructor.
Grading scheme (The final report must be worth at least 50% of final grade): Laboratory performance (50%); Final report (50%).
Project status: This project is taken. The professor has no more '396' projects this term.
Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves: Handling chemicals.