396 Undergraduate Research Project Application Form

INSTRUCTIONS - PROFESSORS: Fill out Sections A & B then submit this form online. (You will receive an email copy of the form. The Office for Undergraduate Research in Science will also post the project online, indicating whether the project is open for students to apply or taken.) DONE

INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it after it has been posted. Either way, print this form. Complete and sign Section C on the hardcopy. Ask your supervisor to sign Section D. Take it to the department corresponding to the course number in Section A (this may or may not be your own department). Do not register for a '396' course on Minerva until you receive departmental permission.

 INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, notify student. If approved, please give student permission to register on Minerva, and fax this form (with signatures) to the Office for Undergraduate Research in Science at 514-398-8102.

QUESTIONS OR FEEDBACK? Contact Victor Chisholm by email, or phone 514-398-5964.

Name: Dr. John Hiscott
Email: john.hiscott [at] mcgill.ca
Phone: 514-340-8222
Website: www.johnhiscottlab.ca
Supervisor's department: Microbiology and Immunology
Supervisor's department (if none of the above)  
Course number: MIMM396 (Microbiology and Immunology)
Term: Winter 2008-2009
Project start date: TBD
Project end date: TBD
Project title: Enhancement of oncolytic effect of Vesicular Stomatitis Virus
Project description: Vesicular Stomatitis Virus (VSV) hqas recently emerged as a potentially antitumor agent. This virus replicates and kills the majority of immortalized and transformed acell lines, while failing to replicate efficiently in normal cells. The current hypothesis is that aspects of the antiviral response are compromised in maligant cells, thus afforcing a cellular environment that allows for virul replication, resulting in oncolysis. We are currently investigating the use of VSV in the treatment of several cancers and are working to enhance its oncolytic effect by genetically engineering the virus to express various gene products and combining the VSV treatment with different chemo therapies.
Prerequisite: Other: please specify below
Other prerequisite, if applicable: MIMM212 or equivalent laboratory course, 1 year completed at McGill with CGPA of 3.0 or higher
Grading scheme (The final report must be worth at least 50% of final grade): Performance evaluated by research supervisor (50%) and final report (50%)
Other project information:
Project status - This project is: Taken. The professor has no more '396' projects this term.
How students can apply: N/A; this project is filled.
If other, please specify:  
Ethics, safety, and training
Which of the following, if any, is involved? One or more of the following
Animal subjects [x]
Human subjects [ ]
Biohazardous substances [x]
Radioactive materials [x]
Handling chemicals [x]
Using lasers [ ]
Supervisors are responsible for the ethics and safety compliance of undergraduate students.
Do not complete this section unless/until the student is identified.
McGill ID:  
Email (first.last [at] mail.mcgill.ca):  
Program (E.g., B.Sc. Maj. Chem. Min. Biol.):  
Level (U0 / U1 / U2 / U3):
Student signature - I have not applied for another '396' course in this term:  
Do not complete this section unless/until the student is identified.
Supervisor: I give my permission for the student identified in section C to register for this project under my supervision.
Supervisor's signature:  
Unit chair/director/designate: I certify that this project conforms to departmental requirements for 396 courses.
Unit chair/director/designate's name:  
Unit chair/director/designate's signature: