396 Undergraduate Research Project Application Form

INSTRUCTIONS - PROFESSORS: Fill out Sections A & B then submit this form online. (You will receive an email copy of the form. The Office for Undergraduate Research in Science will also post the project online, indicating whether the project is open for students to apply or taken.) DONE

INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it after it has been posted. Either way, print this form. Complete and sign Section C on the hardcopy. Ask your supervisor to sign Section D. Take it to the department corresponding to the course number in Section A (this may or may not be your own department). Do not register for a '396' course on Minerva until you receive departmental permission.

INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, notify student. If approved, please give student permission to register on Minerva, and fax this form (with signatures) to the Office for Undergraduate Research in Science at 514-398-8102.

QUESTIONS OR FEEDBACK? Contact Victor Chisholm by email, or phone 514-398-5964.

Name: R.B. Lennox
Email: bruce.lennox [at] mcgill.ca
Phone: 514-398-6940
Supervisor's department: Chemistry
Supervisor's department (if none of the above)  
Course number: CHEM396 (Chemistry)
Term: Winter 2008-2009
Project start date: 2009-02-15
Project end date: 2009-04-30
Project title: Electrochemical detection of antigens using the Electrochemical Microfluidic Probe
Project description: An electrochemical micro fluidic probe (EMP), which combines an open micro fluidic system and microelectrodes, buit via microfabrication processes, is under development and improvement at the Micro and NanoBioengineering Lab. An advanced micro fluidic system involving the confined jet and laminar stream of solutions on single cells, is been use as the basis of development of the EMP, which head has the size of a cell (100µm). The ultimate aim of this project is to set-up a spatially and temporally controlled in vitro measurement tool for the electrochemical detection of signalling compounds released from a single cell. Here, the electrochemical part of the probe will be set-up for detecting and measuring proteins quantity excreted by single cells. The main part of this project concerns the study of the electrochemical detection properties. The target proteins will be interleukins and TNFo signaling biomolecules, which are known to play a key role in the signaling cascade involved in the neurogenerative diseases. The student will be involved in the biomolecules immobilization process (i.e., electro-grafting of functionalized antibodies via the electro-addressing of diazonium biomolecules) and he/she will study the detection capacities of the EMP (electrochemistry measurements, including cyclic-voltammetry and impedance spectroscopy.)
Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.
Other prerequisite, if applicable:  
Grading scheme (The final report must be worth at least 50% of final grade): 50% final report, 50% in the laboratory grade.
Other project information:
Project status - This project is: Taken. The professor has no more '396' projects this term.
How students can apply: N/A; this project is filled.
If other, please specify:  
Ethics, safety, and training
Which of the following, if any, is involved? None
Animal subjects [ ]
Human subjects [ ]
Biohazardous substances [ ]
Radioactive materials [ ]
Handling chemicals [ ]
Using lasers [ ]
Supervisors are responsible for the ethics and safety compliance of undergraduate students.
Do not complete this section unless/until the student is identified.
McGill ID:  
Email (first.last [at] mail.mcgill.ca):  
Program (E.g., B.Sc. Maj. Chem. Min. Biol.):  
Level (U0 / U1 / U2 / U3):
Student signature - I have not applied for another '396' course in this term:  
Do not complete this section unless/until the student is identified.
Supervisor: I give my permission for the student identified in section C to register for this project under my supervision.
Supervisor's signature:  
Unit chair/director/designate: I certify that this project conforms to departmental requirements for 396 courses.
Unit chair/director/designate's name:  
Unit chair/director/designate's signature: