Undergraduate Research Project Proposal Form

INSTRUCTIONS - PROFESSORS: Fill out Sections A & B then submit this form online. (You will receive an email copy of the form. The Office for Undergraduate Research in Science will also post the project online, indicating whether the project is open for students to apply or taken.) DONE

INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it after it has been posted. Either way, print this form. Complete and sign Section C on the hardcopy. Ask your supervisor to sign Section D. Take it to the department corresponding to the course number in Section A (this may or may not be your own department). Do not register for a '396' course on Minerva until you receive departmental permission.

INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, notify student. If approved, please give student permission to register on Minerva, and fax this form (with signatures) to the Office for Undergraduate Research in Science.

QUESTIONS OR FEEDBACK? Contact Victor Chisholm by email, or phone 514-398-5964.

Name: Prof. Ken Hastings (Co-Supervisor: Paul Clarke)
Email: ken.hastings [at] mcgill.ca (ken.hastings) -at-mcgill.ca
Phone: 514 398 1852
Supervisor's department: Biology (Associate Member)
Supervisor's department (if none of the above) MNI
Course number: BIOL396 (Biology)
Term: Winter 2008-2009
Project start date: Jan 5 2009
Project end date: April 30 2009
Project title: Fos Assay optimization and chlorisondamine's effects of Nicotine in the brain
Project description: 1) An initial series of ~3 experiments to try to improve the fos assay by taking an amphetamine-treated rat that has lots of fos expression, then insert an extra step in the fos staining protocol and see if it improves the noise signal ratio fos staining.

2) Use fos staining to ask whether nicotine's ability to induce fos in different brain areas is completely backed by systematic administration of the quasi-irreversible nicotinic antagonist chlorisondamine. Chlorisondamine would be very useful tool if we could be confident that it blocks nicotine's effects throughout the brain.
Prerequisite: 1 term completed at McGill + CGPA ≥ 3.0; or permission of instructor.
Other prerequisite, if applicable:  
Grading scheme (The final report must be worth at least 50% of final grade): 50% on lab performance, 50% on Final Report
Other project information:
Project status - This project is: Taken
How students can apply: (N/A, this project is taken.)
If other, please specify:  
Ethics, safety, and training
Which of the following, if any, is involved? One or more of the following
Animal subjects [x]
Human subjects [ ]
Biohazardous substances [ ]
Radioactive materials [ ]
Handling chemicals [x]
Using lasers [ ]
Supervisors are responsible for the ethics and safety compliance of undergraduate students.
Do not complete this section unless/until the student is identified.
McGill ID:  
Email (first.last [at] mail.mcgill.ca):  
Program (E.g., B.Sc. Maj. Chem. Min. Biol.):  
Level (U0 / U1 / U2 / U3):
Student signature - I have not applied for another '396' course in this term:  
Do not complete this section unless/until the student is identified.
Supervisor: I give my permission for the student identified in section C to register for this project under my supervision.
Supervisor's signature:  
Unit chair/director/designate: I certify that this project conforms to departmental requirements for 396 courses.
Unit chair/director/designate's name:  
Unit chair/director/designate's signature: