BIOC 396, Undergraduate Research Project Proposal Form: Characterization of Viperin-FPPS Interaction (Prof. A. Pause)

INSTRUCTIONS - PROFESSORS: Fill out Sections A & B then submit this form online. (You will receive an email copy of the form. The Office for Undergraduate Research in Science will also post the project online, indicating whether the project is open for students to apply or taken.) DONE
INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it after it has been posted. Either way, print this form. Complete and sign Section C on the hardcopy. Ask your supervisor to sign Section D. Take it to the department corresponding to the course number in Section A (this may or may not be your own department). Do not register for a '396' course on Minerva until you receive departmental permission.
INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, notify student. If approved, please give student permission to register on Minerva, and fax this form (with signatures) to the Office for Undergraduate Research in Science.
QUESTIONS OR FEEDBACK? Contact Victor Chisholm by email, or phone 514-398-5964.
SECTION A: SUPERVISOR INFORMATION
Name: Dr. Arnim Pause
Email: arnim.pause [at] mcgill.ca
Phone: 514-398-1521
Website:
Supervisor's department: Biochemistry
Supervisor's department (if none of the above)
Course number: BIOC396 (Biochemistry)
SECTION B: PROJECT INFORMATION
Term: Fall 2009-2010
Project start date: September 1, 2009
Project end date: December 3, 2009
Project title: Characterization of Viperin-FPPS Interaction
Project description: Viperin is an interferon inducible protein implicated in innate immunity against viral infections. Viperin binds to and inhibits FPPS, a protein involved in membrane maintenance, to disrupt the ability of viruses to escape from an infected cell. We will be characterizing the protein-protein interaction between viperin and FPPS by generating constructs containing truncations of the proteins. These constructs will be overexpressed in mammalian cells and, using assays of immunoprecipitation and western blot, we will determine viperin-FPPS interactions.
Prerequisite: 1 term completed at McGill + CGPA ≥ 3.0; or permission of instructor.
Other prerequisite, if applicable:  
Grading scheme (The final report must be worth at least 50% of final grade): Final grade shall be based on laboratory performance (50%) and a final written report (50%).
Other project information:
Project status - This project is: Taken. The professor has no more '396' projects this term.
How students can apply: N/A; this project is filled.
If other, please specify:  
Ethics, safety, and training
Which of the following, if any, is involved? One or more of the following
Animal subjects [ ]
Human subjects [ ]
Biohazardous substances [x]
Radioactive materials [ ]
Handling chemicals [x]
Using lasers [ ]
Supervisors are responsible for the ethics and safety compliance of undergraduate students.
SECTION C: STUDENT INFORMATION
Do not complete this section unless/until the student is identified.
Name:
McGill ID:
Email (first.last [at] mail.mcgill.ca):
Phone:  
Program (E.g., B.Sc. Maj. Chem. Min. Biol.):
Level (U0 / U1 / U2 / U3):
Student signature - I have not applied for another '396' course in this term:  
SECTION D: APPROVALS.
Do not complete this section unless/until the student is identified.
Supervisor: I give my permission for the student identified in section C to register for this project under my supervision.
Supervisor's signature:  
Date:  
Unit chair/director/designate: I certify that this project conforms to departmental requirements for 396 courses.
Unit chair/director/designate's name:  
Unit chair/director/designate's signature:  
Date: