Synaptic Plasticity of Neocortical Circuits
The Sjöström laboratory is an Associate Professor in the Department of Neurology and Neurosurgery, Centre for Research in Neuroscience at the Research Institute of the McGill University Health Centre. Our research is focussed on the mechanisms and functional consequences of Spike-Timing-Dependent Plasticity (STDP) in neocortical microcircuits. To understand the role and mechanisms of this form of plasticity, we employ two-photon laser scanning microscopy, neurotransmitter uncaging, optogenetic tools, quadruple whole-cell recordings, and computational modelling.
Over the years, the Sjöström team has been funded by the UK Medical Research Council, the Royal Society, the European Community, the Biotechnology and Biological Sciences Research Council, the Savoy Foundation, the Canada Foundation for Innovation, the Natural Sciences and Engineering Research Council of Canada, and Canadian Institutes of Health Research.