Publications April 2026

A positive feedback loop between sensory and octopaminergic neurons underlies nociceptive plasticity in Drosophila larvae.

Boivin JC, Zhao YQ, Zhu J, Dakin JT, Ning J, Ohyama T.

PLoS Genet. 2026 Apr 28;22(4):e1012122. doi: 10.1371/journal.pgen.1012122. Online ahead of print.

PMID: 42048383

Responsible artificial intelligence integration framework for psychiatric guidelines

S Mendlovic, I Frankova, E Vermetten, D Wasserman… - International Journal of …, 2026

Study title: Determining the feasibility of a trial to determine the impact of a physiotherapist-led primary care model for low back pain: A pilot cluster randomized …

J Miller, K Varette, C McClintock, C Donnelly, J Marsh… - 2026

Beyond the Benefit of Doubt: Biases and Credibility in the Adjudication of Chronic Pain

RD Assis, SP Cohen, H Clarke, N Mittal, MA Fitzcharles - Journal of Law, Medicine & …, 2026

Aryl hydrocarbon receptor orchestrates transcriptomic, non-coding and splicing programs that drive human lung epithelial responses to vaporized cannabis in vitro.

Wilson ET, Eidelman DH, Baglole CJ.

Arch Toxicol. 2026 Apr 15. doi: 10.1007/s00204-026-04362-7. Online ahead of print.

PMID: 41984095

A Decade of Leadership and Impact: Celebrating 10 Years of the ORS Spine Section

…, D Purmessur, N Vo, U Zehra, NO Chahine, L Haglund… - JOR Spine, 2026

TRPC6-Mediated Ca 2+ Influx Activates MAPK and NFκB Signaling and Elicits Pro-Inflammatory and Catabolic Responses in Human Intervertebral Disc Cells.

V Puvanesarajah, A Mesfin, JP Japa, K Yoon… - Cells, 2026

Q14. Can/should we define a minimum level/size for each pain-dependent behavioral outcome that is relevant/clinically meaningful? This would be both the size of …

S Zaki, C Blaker, L Arendt-Nielson, V Chapman

Enhancing Interpretability of Patient-Reported Outcomes Measurement Information System (PROMIS) and Related Measures in Rehabilitation Populations: A Systematic Review of Clinical and Research Applications.

Alhasani R, Ataman R, Nafees Z, Luong A, Auneau-Enjalber L, Quigley A, Michael HU, Ahmed S.

Arch Phys Med Rehabil. 2026 Apr;107(4):778-783. doi: 10.1016/j.apmr.2025.11.017. Epub 2025 Dec 1.

PMID: 41338482

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Targeting breast cancer senescence in 3D models of bone metastasis.

Hamburger ECB, Garakani MM, Ghazizadeh S, Alfaisali S, Ouellet JA, Weber MH, Garzia L, Haglund L, Rosenzweig DH.

Breast Cancer. 2026 Apr 10. doi: 10.1007/s12282-026-01857-0. Online ahead of print.

PMID: 41961223

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Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain.

Lister KC, Wong C, Uttam S, Parisien M, Stecum P, Brown N, Cai W, Ho-Tieng D, Hooshmandi M, Gu N, Amiri M, Beaudry F, Jafarnejad SM, Tavares-Ferreira D, Inturi NN, Mazhar K, Zhao HT, Fitzsimmons B, Gkogkas CG, Sonenberg N, Price TJ, Diatchenko L, Atlasi Y, Mogil JS, Khoutorsky A.

Elife. 2026 Apr 10;13:RP100451. doi: 10.7554/eLife.100451.

PMID: 41960785

Sex Differences in P-Tau217, Tau Aggregation, and Cognitive Decline.

Coughlan GT, Ourry V, Townsend D, Klinger H, Brown JA, Cuppels M, Betthauser T, Langhough R, Cody K, Seto M, Birkenbihl C, Li A, Farrell M, Thibault E, Kivisäkk Webb P, Arnold S, Rissman RA, Properzi M, Schultz A, Johnson K, Langford O, Donohue MC, Villeneuve S, Johnson SC, Yang HS, Manson JE, Sperling R, Buckley RF; A4 Study Team, the Alzheimer’s Disease Neuroimaging Initiative, and the PREVENT-AD Research Group.

JAMA Neurol. 2026 Apr 1;83(4):369-381. doi: 10.1001/jamaneurol.2025.5670.

PMID: 41697669

*Beyond miRNA Cargo Profiles: Anti-Inflammatory Roles of Extracellular Vesicle-Enriched miRNAs Derived From Human Intervertebral Disc Cells Unveiled by Functional Testing.

Li L, Sun A, Ghazizadeh S, Al-Jallad H, Upshaw K, Alfaisali S, Ouellet J, Jarzem P, Cherif H, Haglund L.

J Extracell Biol. 2026 Apr 7;5(4):e70127. doi: 10.1002/jex2.70127. eCollection 2026 Apr.

PMID: 41953753

Adverse Effects and Perceived Benefits of Medications in Children with Chronic Noncancer Pain

K Niburski, N Mohamed, D Dundaru-Bandi… - Frontiers in Pain Research

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A new and less invasive surgical approach to the mouse spared nerve injury model of peripheral neuropathic pain.

Rought R, Rodrigues R, Sharif-Naeini R, Stone LS, Coderre TJ, Ribeiro-da-Silva A, Millecamps M.

J Neurosci Methods. 2026 Mar 28;431:110751. doi: 10.1016/j.jneumeth.2026.110751. Online ahead of print.

PMID: 41905537