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Chemical Society Seminar: Ivan Aprahamian - Hydrazone-Based Switches and Functional Materials


Maass Chemistry Building Room 112, 801 rue Sherbrooke Ouest, Montreal, QC, H3A 0B8, CA


For the past few years we have been developing structurally simple, easy to make, modular, and tunable hydrazone-based functional materials (e.g., switches, sensors and fluorophores).1 This presentation will deal with our recent advances with these systems, with an emphasis on newly developed photochromic compounds2 that exhibit many interesting properties, including emission ON/OFF toggling in solution (see below) and the solid-state.3 The integration of these photochromic compounds into liquid crystals4 and liquid crystalline elastomers,5 and their use in the templated-synthesis of g-cyclodextrin,6 will also be discussed.


Representative references:

1. B. Shao, I. Aprahamian Chem 2020, 6, 2161–2173.

2. (a) H. Qian, S. Pramanik, I. Aprahamian J. Am. Chem. Soc. 2017, 139, 9140−9143 (b) Q. Li, H. Qian, B. Shao, R. P. Hughes, I. Aprahamian J. Am. Chem. Soc. 2018, 140, 11829–11835

3. B. Shao, M. Baroncini, H. Qian, L. Bussotti, M. Di Donato, A. Credi, I. Aprahamian J. Am. Chem. Soc. 2018, 140, 12323–12327

4. M. J. Moran, M. Magrini, D. Walba, I. Aprahamian J. Am. Chem. Soc. 2018, 140, 13623–13627

5. A. Ryabchun, Q. Li, F. Lancia, I. Aprahamian, N. Katsonis J. Am. Chem. Soc. 2019, 141, 1196–1200

6. S. Yang, D. Larsen, M. Pellegrini, S. Meier, D. F. Mierke, S. R. Beeren, I. Aprahamian, Chem 2021, 7, 2190–2200.


Professor Aprahamian received all his degrees (BSc in 1998, MS in 2000, and PhD in 2005) from the Hebrew University of Jerusalem, Israel. His doctoral research focused on NMR spectroscopic studies of alkali metal reduced polycyclic aromatic hydrocarbons. He then carried out postdoctoral researcher in Professor Sir Fraser Stoddart's group at UCLA, where he focused on the synthesis of switchable and highly-ordered interlocked molecules in the form of bistable [n]rotaxanes. Dr. Aprahamian joined the faculty at Dartmouth College in August 2008, and was promoted to Associate Professor in 2014, and Full Professor in 2019. His research group focuses on using structurally simple, modular, and tunable hydrazone-based building blocks in the development of adaptive functional materials, including switches, sensors and fluorophores. Dr. Aprahamian is the recipient of the 2016 Cram Pederson Lehn Award in Supramolecular Chemistry, and is a Humboldt and Royal Society of Chemistry Fellow.

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