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On this page: iPSC Protocol Videos  | Publications | Preprints | Accessing iPSCs | EDDU Community and Resource Hub

iPSC Culture Protocol Videos

Watch our iPSC culture protocol videos to learn how to culture iPSCs and iPSC-derived neural cells.

English, French, Portuguese, and Spanish videos are available now, with more languages coming soon!

 

At the EDDU, we developed a method with microfabricated disk (EB disk-948 from eNUVIO) to scale up the generation of hMOs (human midbrain organoids). This opens up the possibility to generate larger numbers of hMOs, in a manner that minimizes the amount of labor required, while decreasing variability and maintaining the viability of these hMOs over time.

This video will describe the methodology to generate hMOs from a single EB-Disk containing 948 microwells.

The Neuro’s EDDU is also pleased to share our updated  protocol for generating dopaminergic neurons from  iPSCs through the use of a  Microfabricated EB Disk. You can access the protocol here: https://zenodo.org/record/8256637 

 


Latest Publications

To access all of the EDDU's publications, please visit our Community and Resource Hub

 

MerTK is a mediator of alpha-synuclein fibril uptake by human microglia

September 2023

Marie-France Dorion et al. 

Scientific diagram of human microglia and mer-TK, and its interaction with a-syn fibrils.

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Transcriptional dysregulation and impaired neuronal activity in FMR1 knock-out and Fragile X patients’ iPSC-derived models

October 2023

Gilles Maussion, Cecilia Rocha et al. 

Image that represents the paper: Transcriptional dysregulation and impaired neuronal activity in FMR1 knock-out and Fragile X patients’ iPSC-derived models

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Preprints

 

Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations

October 2023

Vincent Soubannier et al. 

Microscopy of astrocytes taken by scientist Vincent Soubannier.

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The Use of a SOX10 Reporter Towards Ameliorating Oligodendrocyte Lineage Differentiation from Human Induced Pluripotent Stem Cells

December 2023

Valerio Piscopo et al.

Microscopy of oligodendrocytes from Valerio's preprint paper.

Read More

 

 


How to Access iPSCs

At the EDDU we have a catalogue of iPSC lines from healthy individuals and from patients with neurological disorders that can be freely accessed for a small fee. Our cells are for experimental use only.

To access the cells, please contact cbig.mni [at] mcgill.ca (C-BIG). Click here for further instructions on accessing cells.

To learn more about how the cells are made or for general inquiries, contact us at neuroeddu.mni [at] mcgill.ca.

iPSC Catalogue last updated: August 2023

View the iPSC Catalogue

 


Visit our Community and Resource Hub

To access the EDDU’s Open Science resources including our publications, presentations, protocols, and software please visit our Community and Resource Hub.

Access The Neuro EDDU Community and Resource Hub

 

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Contact Us

Email or call us to schedule a visit to the EDDU and to meet the team.

Early Drug Discovery Unit
The Neuro
3801 University
North Wing B150
Montreal, QC H3A 2B4

 

For general inquiries: Email us at neuroeddu.mni [at] mcgill.ca

For career and training opportunities: Contact Genevieve Dorval by genevieve.dorval [at] mcgill.ca (email).

For operations and lab oversight: Contact Genevieve Dorval by genevieve.dorval [at] mcgill.ca (email).

For accessing iPSCs: Please email us at neuroeddu.mni [at] mcgill.ca.

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Collaborate with Us

Interested in partnering with us? neuroeddu.mni [at] mcgill.ca (Email us) 

Join Us

Want to join our team? Visit Neuro Careers for available positions.

For training and staff positions, please email genevieve.dorval [at] mcgill.ca (Genevieve Dorval).

Support Us

If you would like to support our work, visit Neuro Giving for more information.

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The Neuro (Montreal Neurological Institute-Hospital) is a bilingual academic healthcare institution. We are a McGill research and teaching institute; delivering high-quality patient care, as part of the Neuroscience Mission of the McGill University Health Centre. We are proud to be a Killam Institution, supported by the Killam Trusts.

 

 

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