BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20260525T184412EDT-8427waSjOr@132.216.98.100 DTSTAMP:20260525T224412Z DESCRIPTION:The 2025-2026 Neuro Epilepsy Lecture Series covers hot topics i n basic and clinical epilepsy research. Speakers will include distinguishe d leaders and rising stars\, with the goal of bridging basic research and clinical perspectives.\n\n\nRegister for In-Person\n\nTo watch online\, cl ick here\n\n\nFrom Bore to Bedside: Promises and Pitfalls of Translational Epilepsy Imaging\n\nAbstract: MRI and related imaging techniques are cent ral diagnostic tools in neurology and powerful instruments in modern neuro science. This dual role creates considerable opportunities to translate sc ientific insights to the bedside\, which are not yet fully leveraged. Rece nt work on blood–brain barrier dysfunction in people with epilepsy across different field strengths demonstrates that epileptic seizures leave measu rable “traces” over seconds to hours\, opening new avenues for functional seizure imaging that can inform presurgical evaluation. Algorithms for aut omated detection of potentially epileptogenic lesions developed today may become tomorrow’s clinical research and development systems\, ultimately s upporting resective epilepsy surgery in individuals with previously undete cted lesions (MRI-negative). While attention often centers on artificial i ntelligence alone\, meaningful evaluation requires careful consideration o f human performance and human-AI interaction. Ultra-high-field MRI offers unique opportunities for both research and clinical practice\, yet early s tudies temper clinical expectations that it will substantially reduce the number of MRI-negative individuals. In contrast\, ultra-low-field MRI prov ides encouraging prospects for other populations of people with epilepsy. Translation\, however\, is not unidirectional. Clinical observations in ep ilepsy can also inform fundamental neuroscience: histories of people with epilepsy – such as individuals after hemispherotomy – offer unique insight s into plasticity\, functional redundancy of the brain\, and the isolated hemisphere as an “island of awareness.” Beyond methodology\, this talk hig hlights key translational challenges at the intersection of open science a nd clinical reality\, including fragmented datasets\, privacy regulation\, and the need for secure data-trusteeship models that enable large-scale\, legally compliant research collaboration. Together\, these perspectives o utline both the promise and the pitfalls of bringing next-generation neuro imaging from the MRI bore to the bedside in epilepsy care. Finally\, the t alk turns to a second\, often overlooked\, translational dimension of epil epsy imaging: ensuring that its benefits reach people with epilepsy in res ource-limited settings.\n\nTheodor Rüber\n\nEpileptologist\, Neurologist\, and clinician-scientist\, University Hospital Bonn\n\n\n\nTheodor Rüber\, MD\, is an epileptologist/neurologist\, and clinician-scientist at the Un iversity Hospital Bonn in Germany\, where he leads the Translational Neuro imaging and Global Epileptology research groups and serves as Managing Dir ector of the Center for Medical Data Usability and Translation (CMDT). His clinical focus spans complex epilepsies\, presurgical evaluation\, long-t erm monitoring\, and advanced MRI – including ultra-high- and ultra-low-fi eld imaging. Dr. Rüber is also founder of the data-altruism non-profit dey ond and multiple global health and cultural organizations. Recipient of na tional and international awards\, including the Order of Merit of the Fede ral Republic of Germany and the NRW Young Scientist Award\, he is committe d to advancing data-enabled epileptology\, open science\, and socially res ponsible innovation.\n\n\nThese seminar series are made possible through t he sponsorship of:\n\n\n\n \n\n \n DTSTART:20260205T210000Z DTEND:20260205T220000Z LOCATION:de Grandpre Communications Centre\, The Neuro SUMMARY:Neuro Epilepsy Lecture Series: From Bore to Bedside: Promises and P itfalls of Translational Epilepsy Imaging URL:https://www.mcgill.ca/neuro/channels/event/neuro-epilepsy-lecture-serie s-bore-bedside-promises-and-pitfalls-translational-epilepsy-imaging-369611 END:VEVENT END:VCALENDAR