Other Academic Positions

Positions Available

Research Assistant (Under the supervision of Dr. Alan Evans)

The research assistant will be involved in neuroimaging analysis and research of the lab. The work includes developing imaging data handling processes and pipelines to our existing web‐based data management software interfacing with leading genetics databases and other research data platforms. Work consists of contributing to the design, coding and testing of the web‐based neuroscience research platform, along with publications on the developed pipelines and processes. This position requires working seamlessly with a small team of software development professionals and researchers, as well as the ability to learn and adapt rapidly.

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Academic Associate (Under the supervision of Dr. Angela Genge)

Responsibilities include:

  1. Facilitate, coordinate, enhance and promote McGill’s research and development activities by coordinating and managing clinical trial projects at the Clinical Research Unit at the MNI.
  2. Ensure continuous support to Investigators/Physicians in the delivery of up-to-date activities and information, confirming priorities and timeframes of clinical trial subjects. Read and understand clinical trial protocols. In conjunction with medical staff, oversee medication infusions, monitor and record patient symptoms, collect and transcribe laboratory data.
  3. Interpret information received on patients and select the most appropriate procedures and trials for performing the research and ethics administration activities. Ensure that the activities are performed in accordance with each individual clinical trial protocol and University and sponsors policies and procedures.
  4. Communicate information to medical staff, patients and pharmaceutical companies on new information pertaining to patients, changes to regimens, deadlines in terms of tests to be performed (i.e., CT scan, blood tests, etc), regulatory information, etc.
  5. Teach patients, researchers and nurses to follow protocol according to GCP guidelines.
  6. Help with training for new staff and volunteers in the unit as necessary.
  7. Provide information and advice to researchers on the preparation of the research information.
  8. Liaison between researcher, patient and pharmaceutical company. Attends all internal and external meetings as requested by the medical director and/or the pharmaceutical company for each clinical trial the coordinator has responsibilities.
  9. Functions as a record-keeper in terms of patient information pertaining to the study and is accountable for the follow-up of business.
  10. Oversee purchasing and inventory of supplies needed for the clinical trial.
  11. Perform other administrative duties as required. This includes assisting in co-writing of grant proposals, abstracts and other research papers.

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Research Assistant (Dr. Gary Armstrong's Laboratory)

The research program is focused on the development of zebrafish genetic models of Amyotrophic Lateral Sclerosis (ALS) and conducting basic research to further our understanding of the synaptic and cellular defects that arise in these models.

  • The research assistant (RA) will be responsible for screening new zebrafish lines for specific mutations, this will include being trained in zebrafish husbandry, genomic extraction, PCR and immunohistochemical techniques.
  • To achieve these goals the RA will be expected to provide new ideas and suggestions by reading the literature related to this project. Based on the information gathered, they will help in the optimization of protocols for genotyping and immunostaining.
  • The RA will be given the opportunity to be an author on any publication derive from the work performed. Will be responsible for maintaining these and other zebrafish lines in the animal care facility at the Montreal Neurological Institute and help in the ordering and maintenance of chemicals and reagents need to ensure smooth operation of the laboratory.

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Research Assistant (High Content Platform under Dr. Thomas Durcan, 2 positions)

The candidate will work with the High Content platform team and will be responsible for generating different types of neuronal and glial cell on projects related to the High Content Analysis Platform being established at the MNI.

Duties will include working with team members on several drug discovery projects and liaising with program directors. The applicant will work with disease-relevant induced pluripotent stem cell (iPSCs) derived cell-based assays for neurodegenerative disorders. Generate new iPSC lines from patient samples, and for the maintenance of these iPSCs as needed on a project by project basis. Responsible on generating neurons and glial cells from iPSCs for different projects and assist in developing Standard Operating Protocols (SOPs) to industry-standard for deriving a wide range of neurons. Collect and interpret results from these research experiments that will be included in future publications. Prepare reports and update laboratory procedures on a regular basis, along with other related duties as assigned.

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Research Assistant (Neurodegenerative Diseases under Dr. Edward Fon)

The research assistant will be involved in ongoing projects in the field of mitochondrial biology, working independently and with team members, will help design innovative experiments conducting and developing fluorescence microscopy assays focused on Parkinson’s disease. Will work on the improvement of differentiation protocols for iPSC‐derived glial cells in disease‐relevant models, actively collaborating with other members of the iPSC/CRISPR platform.

  1. Support the further development of fluorescent microscopy assays.
  2. Training of students in microscopy techniques both in vivo and in vitro.
  3. Propagating and differentiating human pluripotent stem cells.
  4. Ability to coordinate research efforts both internally and with collaborators and their teams.
  5. Assist lab members, notably with image acquisition, processing and data analysis.
  6. Troubleshooting.
  7. Prepare and present reports and technical presentations, and participate in the writing of research applications as part of this project.
  8. Maintain high-end microscopy equipment.
  9. Others duties as required.

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Research Assistant (Radiochemistry Unit under Dr. Gassan Massarweh)

The research assistant will be involved in research aimed at the synthesis of novel radiopharmaceuticals for Positron Emission Tomography. After an appropriate time of skill adjustment, he/she will independently refine and optimize experimental design and methods for the introduction of various radionuclides such as C11, 18F, 68Ga and iodine isotopes into organic molecules.

  1. He/she will be involved in the routine daily production of radiopharmaceuticals at the McConnell Brain Imaging Centre.
  2. He/she will be properly trained by the experienced senior staff in synthesizing carbon‐11 and fluorine‐18 radiopharmaceuticals.
  3. He/she will then independently perform the synthesis and quality control of radiopharmaceuticals for human and research use.
  4. He/she will carry out organic synthesis.
  5. He/she will assist in the operation and maintenance of the cyclotron radiochemistry synthesis modules and quality control equipment.
  6. He/she will be responsible for planning and conducting all necessary steps involved in organic and radiotracer synthesis.
  7. May be required to assist with FDG production (early morning shift (4am))

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Research Assistant (Radiochemistry Unit under Dr. Gassan Massarweh; Part‐Time 2 days/week)

The research assistant will be involved in research aimed at the synthesis of novel radiopharmaceuticals for Positron Emission Tomography. After an appropriate time of skill adjustment, he/she will independently refine and optimize experimental design and methods for the introduction of various radionuclides such as C11, 18F, 68Ga and iodine isotopes into organic molecules.

  1. He/she will be involved in the routine daily production of radiopharmaceuticals at the McConnell Brain Imaging Centre.
  2. He/she will be properly trained by the experienced senior staff in synthesizing carbon‐11 and fluorine‐18 radiopharmaceuticals.
  3. He/she will then independently perform the synthesis and quality control of radiopharmaceuticals for human and research use.
  4. He/she will carry out organic synthesis.
  5. He/she will assist in the operation and maintenance of the cyclotron radiochemistry synthesis modules and quality control equipment.
  6. He/she will be responsible for planning and conducting all necessary steps involved in organic and radiotracer synthesis.
  7. May be required to assist with FDG production (early morning shift (4am))

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Research Associate (Dr. Edward Ruthazer's Laboratory)

The candidate will work independently on basic research projects in the laboratory of Dr. Edward Ruthazer at the MNI. Specific duties include:

  • Understand how microglial derived molecules alter synaptic function and brain development.
  • Use a variety of cell biological, molecular, and in vivo imaging assays to determine the role of neuroinflammation in neurodevelopmental disorders such as schizophrenia.
  • Design methodology and perform experiments, will work with collaborative teams on the multidisciplinary aspects of the research projects.
  • Analyze the data, write drafts of manuscripts, and contribute to the writing of grants.
  • Participate in the supervision of full‐time technician(s) and of undergraduate and graduate trainees when required.

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Research Assistant (Dr. Philippe Huot's Laboratory)

The Research Assistant will be involved in research that seeks to discover new therapeutics to treat Parkinson’s disease and complications of chronic dopamine replacement therapy.

  1. Conduct experiments with several animal models of Parkinson’s disease, including rodents and primates. Generate animal models and perform behavioral experiments with experimental drugs.
  2. Induction of parkinsonism through administration of MPTP and 6‐OHDA, and rating abnormal involuntary movements (AIMs) will be performed on a regular basis.
  3. Conduct post‐mortem experiments, including autoradiographic binding, that aim at identifying the mechanisms at play in complications of dopamine replacement therapy such as dyskinesia.
  4. Independently design behavioral pharmacological and post‐mortem experiments that aim at understanding the mechanisms of, and discovering new therapies for, dyskinesia and psychosis in Parkinson’s disease.
  5. Be responsible for the design, development, execution and refinement of the experimental protocols.
  6. Carry out statistical data analysis and participate in data interpretation.
  7. Design and execute experiments and analyze data independently with minimal supervision. Analyze and prepare the data in final forms for presentation. Prepare text and figures for manuscripts and will be a contributing author to the resulting publications.

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Research Associate (Laboratory of Brain and Cognition)

The candidate will work independently on basic research projects in the laboratory of Dr. Spreng. The work will focus on understanding the neural and biochemical basis of attention in the human brain, both in normal cognitive aging and in abnormal cognitive aging caused by neurodegenerative pathology, e.g. Alzheimer’s disease.

The candidate must have strong computational/analytical skills and an ability to work with ‘big data’, i.e. mining and analyzing large multisite databases such as the Alzheimer’s Disease Neuroimaging Initiative (ADNI).

Acquire and analyze structural magnetic resonance imaging (MRI) data, functional MRI data, and magnetic resonance spectroscopy data.

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Academic Associate (Group Leader) Clinical Trial and IIT Development and Management

  • Facilitate, coordinate, enhance and promote McGill’s research and development activities by coordinating and managing clinical trial projects at the Clinical Research Unit at the MNI with an emphasis new program development, grant submission, Health Canada submissions and IITs.
  • Develop new projects under area of expertise with investigator, industry and other partners including IIT’s
  • Liaison between researcher, patient and pharmaceutical sponsors. Attends all relevant internal and external meetings as requested for each clinical trial for which the group leader has responsibilities.

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Research Assistant (Neuroimaging of Epilepsy)

The research assistant will work on research projects in epilepsy using multi‐modal imaging including magnetic resonance imaging (MRI), functional MRI and diffusion tensor imaging (DTI). Will design new algorithms for the segmentation of cortical and subcortical structures, and methodologies and computational models of epileptogenic brain lesions. Will be expected to maintain and expand the laboratory infrastructure in terms of existing image processing algorithms and analytical pipelines, as well as work with collaborative teams on the multidisciplinary aspects of the research projects. Will participate to data analysis and drafts of manuscripts. Moreover, he/she will instruct students in the lab on the use of image analysis tools, if required.

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Research Associate (De Villers-Sidani Laboratory, part-time)

The De Villers‐Sidani lab is seeking a qualified candidate to work independently with the design and writing of experimental protocols aimed at studying the role of age‐related hearing loss and hearing aid use on the cognitive profiles and brain function as assessed by magneto‐encephalography and functional MRI in human subjects.

  • Troubleshoot technical issues arising from the aforementioned experiments and is expected to develop the analyses routines necessary for the data generated.
  • Prepare reports and manuscripts based on the findings obtained and present them at scientific meetings and in peer‐reviewed journals.
  • Participate with grant writing for both salary and operating support for the lab.
  • Co‐supervise graduate and undergraduate students currently completing their studies in the laboratory.

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Research Associate (High Content Platform)

The candidate will work independently and be responsible for performing wet-bench science on projects related to the High Content Analysis Platform being established at the MNI. Duties will include working with team members on a number of drug discovery projects, liaising with program directors, conducting screening of compounds on a high content platform and analysis of high content data. The applicant will develop assays using neurons differentiated from induced pluripotent stem cell (iPSCs) derived from patients with Parkinson’s disease and other neurodevelopmental disorders.
The successful applicant will:

  • Establish and design the protocols for assays that use iPSC-derived neurons in several drug discovery projects.
  • Conduct analysis of screening data including establishing parameters for hit selection.
  • Independently carry out projects to completion.
  • Write and edit SOPs, scientific reports, and participate in the writing of research applications as part of this project
  • Assist other lab members with aspects of projects related to iPSC-derived neurons and assay development.
  • Prepare and present reports and technical presentations to internal scientific groups.
  • Other related duties as assigned.

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Research Assistant (High Content Platform) - 2 positions

Responsible for adapting disease-relevant assays developed with neurons from induced pluripotent stem cell (iPSCs) onto a High Content Analysis platform for the screening of small molecules on a number of drug discovery projects focused on neurodegenerative disorders.

  • Assist in the development and implementation of these high-content assays and co-ordinate the screening and analysis of findings that come from these assays.
  • Assist to develop assays with iPSC-derived neurons for medium throughput high content screens utilizing robotic equipment.
  • Work with other members of the team in helping to complete the analysis of screening data including establishing parameters for hit selection.
  • Maintain iPSCs and work on generating neurons from iPSCs for different projects.
  • Assist in developing Standard Operating Protocols (SOPs) to industry-standard for deriving a wide range of neurons
  • Prepare reports and technical presentations for external scientific groups
  • Review and update laboratory procedures as required.
  • Assist with the maintenance, calibration, and qualification of all laboratory instruments and equipment.

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Research Assistant (Radiochemistry Unit)

The research assistant will be involved in research aimed at the synthesis of novel radiopharmaceuticals for Positron Emission Tomography. After an appropriate time of skill adjustment, he/she will independently refine and optimize experimental design and methods for the introduction of various radionuclides such as C11, 18F, 68Ga and iodine isotopes into organic molecules.

  1. He/she will be involved in the routine daily production of radiopharmaceuticals at the McConnell Brain Imaging Centre.
  2. He/she will be properly trained by the experienced senior staff in synthesizing carbon‐11 and fluorine‐18 radiopharmaceuticals.
  3. He/she will then independently perform the synthesis and quality control of radiopharmaceuticals for human and research use.
  4. He/she will carry out organic synthesis.
  5. He/she will assist in the operation and maintenance of the cyclotron radiochemistry synthesis modules and quality control equipment.
  6. He/she will be responsible for planning and conducting all necessary steps involved in organic and radiotracer synthesis.
  7. May be required to assist with FDG production (early morning shift (4am))

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Research Associate (Rare Neurological Disorders)

The McBride lab is seeking a qualified candidate to work independently on translational aspects of cancer related phenotypes in mouse models, focusing on the role of novel mitochondrial signaling pathways. This project involves high throughput genome‐wide and drug screening approaches that target our pathway, ultimately to identify strategies to target models of liver cancer.

Duties include:

  • Contribute to the intellectual design of experimental approaches to address the role of mitochondrial SUMOylation in pathways of tumour suppression.
  • Develop and troubleshoot high throughput genome-wide and drug screening approaches to reverse the phenotype of MAPL KO liver cells.
  • Test and validate emerging hits using various biochemical, cellular and mouse models.
  • Present research progress to various networks within McGill and at International symposia, where relevant.
  • Participate in annual lab retreats, weekly lab meetings and report regularly on progress.
  • Contribute to the preparation and publication of peer-reviewed manuscripts.
  • Review and update laboratory procedures as required.
  • Assist with the training of staff on equipment use, development and implementation of assays within the lab.
  • Contribute to the supervision of graduate students and post-doctoral fellows.

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Academic Associate (Junior Research Coordinator, Clinical Research Unit)

  • Facilitate, coordinate, enhance and promote McGill’s research and development activities by coordinating and managing clinical trial projects at the Clinical Research Unit at the MNI.
  • Perform established clinical trial outcome measures including physical and cognitive assessments in numerous disease indications.
  • Ensure continuous support to Investigators/Physicians in the delivery of up-to-date activities and information, confirming priorities and timeframes of clinical trial subjects. Read and understand clinical trial protocols. In conjunction with medical staff, oversee medication infusions, monitor and record patient symptoms, collect and transcribe laboratory data.
  • Interpret information received on patients and select the most appropriate procedures and trials for performing the research and ethics administration activities. Ensure that the activities are performed in accordance with each individual clinical trial protocol and University and sponsors policies and procedures.

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Academic Associate(s) (Junior Research Coordinator, Clinical Research Unit)

  • Facilitate, coordinate, enhance and promote McGill’s research and development activities by coordinating and managing clinical trial projects at the Clinical Research Unit at the MNI.
  • Ensure continuous support to Investigators/Physicians in the delivery of up-to-date activities and information, confirming priorities and timeframes of clinical trial subjects. Read and understand clinical trial protocols. In conjunction with medical staff, oversee medication infusions, monitor and record patient symptoms, collect and transcribe laboratory data.
  • Interpret information received on patients and select the most appropriate procedures and trials for performing the research and ethics administration activities. Ensure that the activities are performed in accordance with each individual clinical trial protocol and University and sponsors policies and procedures.
  • Communicate information to medical staff, patients and pharmaceutical companies on new information pertaining to patients, changes to regimens, deadlines in terms of tests to be performed (i.e., CT scan, blood tests, etc), regulatory information, etc.

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Research Associate (Neurodevelopmental Disorders)

The candidate will work independently on basic research projects in the laboratory of Dr. Edward Ruthazer at the MNI.

  • Understand how glial derived molecules alter synaptic function and brain development.
  • Use a variety of cell biological, biophysical, and in vivo imaging assays to determine the role of D-serine in neurodevelopmental disorders such as schizophrenia.
  • Design methodology and perform experiments, will work with collaborative teams on the multidisciplinary aspects of the research projects.
  • Analyze the data, write drafts of manuscripts, and contribute to the writing of grants.
  • Participate in the supervision of full-time technician(s) and of undergraduate and graduate trainees when required.

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Research Associate (High Content Platform) - 2 positions

Will be responsible for performing wet-bench science on projects related to the High Content Analysis Platform being established at the MNI. Duties will include working with team members on a number of drug discovery projects, liaising with program directors, conducting screening of compounds on a high content platform and analysis of high content data. Will work with disease-relevant induced pluripotent stem cell (iPSCs) derived cell-based assays for neurodegenerative disorders.

  • Work with other members of the team to co-ordinate the day to day running of equipment, assay scheduling and library management.
  • Co-ordinate the screening and high content analysis of cell-based assays on the platform to meet internal and external deadlines.
  • Assist with the training of staff on equipment use, development and implementation of assays on a high content platform and project execution.
  • Perform assay development, medium throughput high content screens utilizing robotic equipment.
  • Conduct analysis of screening data including establishing parameters for hit selection.
  • Independently carry out projects to completion.
  • Prepare and present reports and technical presentations to internal scientific groups
  • Review and update laboratory procedures as required.
  • Along with staff, coordinate required periodic maintenance, calibration, and qualification of all laboratory instruments and equipment.

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