Special Seminar: Gene Editing in Human iPSCs to Model Neurological Disorders


Speaker: Eric Deneault, PhD

Research Associate, Montreal Neurological Institute-Hospital, McGill University

Registration: available now on Eventbrite.

Abstract: My research involves the use of patient-specific induced pluripotent stem cells (iPSCs) and derived neurons as a laboratory model to study the direct genetic causes of neurological disorders such as autism spectrum disorder (ASD) and Parkinson’s disease (PD). An important aspect of my research involves developing new gene editing pipelines with novel clustered regularly interspaced short palindromic repeats (CRISPR) technology, which has made the genome almost as editable as a simple piece of text, ensuring that any base pair in almost any location within the genome can be modified or edited. Isogenic pairs of cell lines, that differ exclusively in the mutation of interest, represents the optimal way to assign direct causality to any phenotype, and to shed light on fundamental molecular questions regarding genetically-complex neurodevelopmental and neurodegenerative disorders such as ASD and PD.

This is a recruitment seminar:

Dr. Deneault is a candidate for a position as an Assistant or Associate Professor (Research) in the Department of Neurology and Neurosurgery at McGill University.

How to participate via Zoom:

1. You can either join a meeting via the invite link or the Meeting ID #.

2. If you click the link it will automatically bring you to the meeting. If you do not have the link and only the meeting ID go to the Zoom application and click “Join a meeting” where it will prompt you to input your name and the Meeting ID #.

3. Use the toolbar at the bottom of your screen to mute/unmute yourself and to enable/disable your video.

Contact Information

Deborah Rashcovsky
Montreal Neurological Institute-Hospital
deborah.rashcovsky [at] mcgill.ca

The Neuro logo McGill logoMcGill University Health Centre logoKillam logo


The Neuro is a McGill research and teaching institute; delivering high quality patient care, as part of the Neuroscience Mission of the McGill University Health Centre. We are proud to be a Killam Institution, supported by the Killam Trusts.




Back to top