iPSC Seminars: Early Drug Discovery Unit (EDDU) (Virtual)
The iPSC Seminar Series at The Neuro
Supported by Healthy Brains for Healthy Lives and STEMCELL Technologies, The Neuro’s iPSC Seminar Series welcomes trainees and senior scientists working with induced pluripotent stem cells (iPSCs) to present their cutting-edge research. The Seminar Series intends to foster collaborations within the network of laboratories working with iPSCs in Montreal, Canada and around the world.
Via Zoom (registration required)
Livestreaming via Vimeo
Speaker 1: Dr. Adedamola (Dammy) Olayanju
Senior Scientist, Manchester BIOGEL, UK
Talk abstract
A major challenge in advancing preclinical studies is the lack of robust in vitro culture systems that fully recapitulate what happens in vivo. Recent advancement in the use synthetic peptide hydrogels - PeptiGels® for several 3D cultures have showed potentials to overcome such limitations owing to their ability to better simulate different tissue microenvironments, thereby allowing the generation of more physiologically and clinically relevant data.
Speaker 2 : Marie-France Dorion
PhD Candidate, Healy and Durcan Labs, The Neuro
Talk abstract
Microglia-driven neuroinflammation is an important feature of Parkinson’s disease (PD). The limited availability of human microglia has prevented the study of their contributions to neurodegenerative diseases. We aim to develop and characterize an induced pluripotent stem cell-derived microglia model to investigate the role of innate immune cells in PD pathogenesis.
