Other Academic Positions

Positions Available

Research Assistant (McConnell Brain Imaging Centre under Dr. Julien Doyon)

Healthy Brains for Healthy Lives (HBHL) is a McGill interdisciplinary initiative that seeks to improve the lives of Canadians by advancing understanding of how the brain functions in health and disease. As part of this initiative, we will conduct a series of studies using behavioral testing, neuroimaging and noninvasive brain stimulation techniques to understand, not only the underlying mechanisms of how shortterm and long-term memories are formed, but also to develop ways to enhance memories in healthy adults, as well as to remediate memory functions in neurological patients. We are looking to hire a Research Assistant (RA) to perform duties associated with data collection and analysis pertaining to these studies. The candidate will be expected to independently (i) make the selection of young and older healthy participants that will be recruited to participate in the different experiments based upon a set of inclusion and exclusion criteria, (2) to keep up to date on the literature in order to inform the team members about relevant scientific papers, and (3) report on a regular basis to the PI’s about the progress made in the experiments. The candidate will be principally responsible for assisting in the development and fine-tuning of the experimental design to evaluate the functional consequences of various experimental manipulations based upon observations and collected data during pilot studies. The incumbent will carry out analysis of both behavioral and neuroimaging data independently with minimal supervision, and will actively participate in the design and execution of further studies towards the set goal. The candidate will analyze and prepare the data in final forms for presentation. He/she will also be required to prepare text and figures for manuscripts. He/she will thus be a contributing author to the resulting publications.

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Research Assistant – MNI IPSC/CRISPR Platform (2 positions under Dr. Thomas Durcan)

The candidate will work with the MNI iPSC/CRISPR platform and will be responsible for generating and maintaining induced pluripotent stem cells (iPSCs), and for generating different types of iPSCderived neurons on projects being established at the MNI. Duties will include working with team members on developing new lines from patient cells, using CRISPR genome editing to edit exiting lines and to work on establishing new protocols for several discovery projects. The selected candidate will also work on establishing and validating cell-based assays as needed on a project by project basis. You will also assist in developing Standard Operating Protocols (SOPs) to industry-standard for working with the different cells used in each assay. Will collect and interpret results from these research experiments that will be included in future publications. Along with these duties, you will also be responsible for preparing reports and updating laboratory procedures on a regular basis, along with other related duties as assigned.

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Academic Associate (Junior Research Coordinator)

Specific duties include:

  • Facilitate, coordinate, enhance and promote McGill’s research and development activities by coordinating and managing clinical trial projects at the Clinical Research Unit at the MNI
  • Perform established clinical trial outcome measures including physical and cognitive assessments in numerous disease indications
  • Ensure continuous support to Investigators/Physicians in the delivery of up-to-date activities and information, confirming priorities and timeframes of clinical trial subjects. Read and understand clinical trial protocols. In conjunction with medical staff, oversee medication infusions, monitor and record patient symptoms, collect and transcribe laboratory data
  • Interpret information received on patients and select the most appropriate procedures and trials for performing the research and ethics administration activities. Ensure that the activities are performed in accordance with each individual clinical trial protocol and University and sponsors policies and procedures.
  • Communicate information to medical staff, patients and pharmaceutical companies on new information pertaining to patients, changes to regimens, deadlines in terms of tests to be performed (i.e., CT scan, blood tests, etc), regulatory information, etc.
  • Teach patients, researchers and nurses to follow protocol according to GCP guidelines.
  • Provide information and advice to researchers on the preparation of the research information.
  • Liaison between researcher, patient and pharmaceutical company. Attends all internal and external meetings as requested by the medical director and/or the pharmaceutical company for each clinical trial the coordinator is responsible for
  • Functions as a record-keeper in terms of patient information pertaining to the study and is accountable for the followup of business.
  • Oversee inventory of supplies needed for the clinical trial.
  • Perform other administrative duties as required.

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Academic Associate (Nurse Manager)

The nurse manager is involved in unit expansion projects such as the creation of a phase I clinical trial unit, the infusion room and the development of satellite units: budgeting of equipment, establishing partnerships with the MNH/MUHC, assessing needs for vendor services, etc.

Specific duties include:

  • Facilitate, coordinate, enhance and promote McGill’s research and development activities by coordinating and managing the nursing team at the Clinical Research Unit at the MNI.
  • Read and understand clinical trial protocols to properly assess and establish operational and logistical requirements and issues at the unit/nursing level to conduct the trial.
  • Understand and supervise the administration and management of medication infusions, laboratory sample collections (draw blood samples, collect urine samples, lumbar punctures etc.), patient symptoms monitoring, laboratory data collection and recording and all other nursing related tasks.
  • Support the nursing team to ensure that patient activities are performed in accordance with clinical trial protocol and University and sponsor policies and procedures.
  • Structure and supervise the nursing staff training logs: GCP, Division 5, internal SOPs and others as required.
  • Develop nursing protocols as needed. Work with MUHC as needed to standardize nursing protocols, policies and procedures.
  • Create and maintain nursing SOPs.
  • Oversees inventory of medical and paramedical supplies: Develop an inventory tracking process, maintains inventory log and identifies best supply providers.
  • Participate in the hiring process of nurses and vendor nurses when needed.
  • Participate in the annual performance evaluation process of the nursing team members.

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Research Associate (MNI iPSC platform, Neurodegenerative Disorders under Dr. Thomas Durcan)

The candidate will work independently and be responsible for performing wet-bench science on projects related to the Mowafaghian Foundation for Autism Spectrum disorders (ASDs) and drug discovery. Duties will include working with team members on a number of discovery projects, liaising with program directors and generating new approaches for working with stem cells generated from patients with ASDs.
The applicant will develop assays using neurons differentiated from induced pluripotent stem cell (iPSCs) derived from patients with ASDs and other neurodevelopmental disorders.
The successful applicant will:

  • Establish and design the protocols for assays that use iPSC-derived neurons in several drug discovery projects
  • Conduct analysis of screening data including establishing parameters for hit selection
  • Independently carry out projects to completion
  • Write and edit SOPs, scientific reports, and participate in the writing of research applications as part of this project
  • Assist other lab members with aspects of projects related to iPSC-derived neurons and assay development
  • Prepare and present reports and technical presentations to internal scientific groups
  • Other related duties as assigned

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Research Associate (Bouchard Intellectual Disabilities platform, Neurodegenerative Disorders under Dr. Edward Fon)

The candidate will work independently and be responsible for leading and coordinating immunohistochemistry projects related to work with tissue samples from neuronal organoids for projects related to intellectual disabilities and other neurodevelopmental disorders. Duties will include working with team members in the ID platform and within other groups including the MNI tissue platform on a number of discovery projects, liaising with program directors within the MNI and implementing and developing new techniques to process, embed, section, stain, and image tissue samples from neuronal organoid and other tissue related to the study of brain disorders. The applicant will work with other groups to identify their needs, and to create new SOPS for obtaining, staining and analyzing new tissue section.
The successful applicant will:

  • Establish protocols for tissue processing, embedding and sectioning different tissue samples using both a microtome and/or a cryostat
  • Develop new SOPs for staining, imaging and analyzing tissue samples
  • Independently carry out projects to completion
  • Write and edit SOPs, scientific reports, and participate in the writing of research applications as part of this project
  • Assist other lab members and trainees with aspects of projects related to histology, tissue sectioning and immunocytochemistry including immunofluorescence and immunohistochemistry
  • Oversee the maintenance of equipment within the platform and train other users on the appropriate use of sectioning and histology equipment
  • Prepare and present reports and technical presentations to internal and external scientific groups
  • Other related duties as assigned

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Research Assistant (McGill Centre for Integrative Neuroscience under Dr. Alan Evans)

The Research Assistant will assist in building an analytic environment to acquire, process and integrate data from EEG, MEG, NIRS, fMRI, DTI and MRI in a common framework. The candidate will be principally responsible for the design, development and fine tuning of the EEG and MEG quantitative analysis methods and toolbox. Will carry out analysis of the platform and the data. She/he will actively participate in the design and execution of further studies towards the set goal.

  • Experience in programming EEG quantitative analysis; EEG inverse problem; statistical methods for high-dimensional problems; brain connectivity; variable classification problem
  • Data analysis; database programming
  • Experience in Matlab programming
  • Mathematical modeling and programming of brain electrical signals
  • Evidence of contributions to successful publishing of research data

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Postdoctoral Researcher (Neuromuscular Unit under Dr. Heather Durham)

We seek one or two enthusiastic and motivated individuals to work with our multidisciplinary team to study pathogenic mechanisms in amyotrophic lateral sclerosis (ALS) and other motor neuron disorders and to apply that knowledge to develop and test therapeutic interventions in preclinical studies. Current projects include:

  1. Investigating chromatin remodeling as a convergent mechanism in ALS and involvement in neuronal stress, using primary culture models mouse models and post-mortem tissue (see https://www.ncbi.nlm.nih.gov/pubmed/28973294)
  2. Testing epigenetic modifying drugs and heat shock protein inducers in tissue culture and mouse models of ALS. Actual duties will be determined according to expertise and goals.

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