Other Academic Positions

Positions Available

Academic Associate (Junior Research Coordinator for the Clinical Research Unit)

Specific duties:

  • Facilitate, coordinate, enhance and promote McGill’s research and development activities by coordinating and managing clinical trial projects at the Clinical Research Unit at the MNI
  • Perform established clinical trial outcome measures including physical and cognitive assessments in numerous disease indications
  • Ensure continuous support to Investigators/Physicians in the delivery of up-to-date activities and information, confirming priorities and timeframes of clinical trial subjects. Read and understand clinical trial protocols. In conjunction with medical staff, oversee medication infusions, monitor and record patient symptoms, collect and transcribe laboratory data
  • Interpret information received on patients and select the most appropriate procedures and trials for performing the research and ethics administration activities. Ensure that the activities are performed in accordance with each individual clinical trial protocol and University and sponsors policies and procedures.
  • Communicate information to medical staff, patients and pharmaceutical companies on new information pertaining to patients, changes to regimens, deadlines in terms of tests to be performed (i.e., CT scan, blood tests, etc), regulatory information, etc.
  • Teach patients, researchers and nurses to follow protocol according to GCP guidelines.
  • Provide information and advice to researchers on the preparation of the research information.
  • Liaison between researcher, patient and pharmaceutical company. Attends all internal and external meetings as requested by the medical director and/or the pharmaceutical company for each clinical trial the coordinator is responsible for
  • Functions as a record-keeper in terms of patient information pertaining to the study and is accountable for the follow-up of business.
  • Oversee inventory of supplies needed for the clinical trial.
  • Perform other administrative duties as required.

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Research Assistant (McConnell Brain Imaging Center under Dr. Julien Doyon)

Primary duties:
We are looking for a highly-motivated and experienced candidate to work on collaborative research projects in the laboratory of Prof. Julien Doyon at the Montreal Neurological Institute (The Neuro). Her/his work will be focused on studying sleep-dependent consolidation of memories in healthy and clinical populations, including healthy young subjects, elderly and Parkinson’s disease patients.

She/he will contribute to planning innovative multimodal imaging studies (EEG, fMRI), supervise data collection, and develop and implement pipelines for multimodal data analysis collected during various physiological states (i.e., resting state, task and sleep). Working in a highly collaborative environment, she/he will also be responsible for organizing meetings and coordinating between teams to effectively promote the multidisciplinary aspects of the research projects. The research activities will also include writing manuscripts, contributing to research grants and peer-reviews, and providing support and supervision of research assistants and graduate trainees.

The candidate will have access to the neuroimaging facilities of the McConnell Brain Imaging Center and the sleep laboratory located at the “Institut universitaire de gériatrie de Montréal” and soon at The Neuro. She/he will also benefit from working in the exceptionally rich research environment of the Neuro with a plethora of opportunities to be up-to-date with the latest developments in the field and to develop new collaborations.

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Research Assistant (Montreal Neurological Institute under Dr. Jean-Baptiste Poline)

Primary duties:
Through support from Canada First Research Excellence Fund, the McGill Healthy Brains for Healthy (HBHL) life initiative (https://www.mcgill.ca/hbhl/) aims at conducting cutting edge research to deliver implementable, clinically effective outcomes in brain and mental health for Canadian citizens. The NeuroHub project is tasked with the construction of a versatile and flexible neuroinformatics infrastructure to foster collaborative and reproducible neuroscience and translational research. The goal of NeuroHub is to advance research with the tools and the informatics environment to improve research efficiency and reusability through the dissemination, documentation, and processing of large and complex research datasets such as the UK Biobank.

The selected candidate will work at the interface of the neuroscience research and clinical user community to support research performed on the platform, contribute to the platform testing, organize training and testing of the platform. The research assistant understands the needs of and interacts with the user community, reports to the Principal Investigator, and becomes a part of a dynamic team of scientists, developers, and coordinators.

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Research Associate (ACElab, McGill Centre for Integrative Neuroscience under Dr. Alan C. Evans)

Primary duties:
The candidate will work independently on image processing projects in the laboratory of Professor Alan C. Evans (ACElab) at the MCIN/MNI. His/her work will be focused on shape and texture analysis and deformation modeling of brain anatomical data, including post mortem and various MRI modalities. He/she is responsible to create, test and document a validation platform for various morphometric analysis tools developed in the ACElab. The candidate should contribute to training students, preparing manuscripts and grants.

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Research Associate (ACElab, McGill Centre for Integrative Neuroscience under Dr. Alan C. Evans)

Primary duties:
The candidate will work independently on basic research projects in the laboratory of Professor Alan C. Evans (ACElab) at the MNI. His/Her work will be focused on understanding connectivity in the developing human brain using multi-modal imaging including magnetic resonance imaging (MRI), functional MRI and diffusion tensor imaging (DTI). Additionally, he/she will use various connectivity measures to understand the origin and etiology of neurodevelopmental disorders including Autism Spectrum Disorders (ASD). He/she will design the necessary research methodology and computational modelling of the changing brain structure and function in normal development and neurodevelopmental disorders. He/she will work with collaborative teams on the multidisciplinary aspects of the research projects and will further analyze the data, write drafts of manuscripts, and contribute to the writing of grants. The candidate will also participate in the supervision of full-time technician(s) and of graduate and summer trainees, if required.

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Research Associate (Neural Circuits Research Group under Dr. Philippe Séguéla)

Primary duties:
The Research Associate will work independently on research projects in the laboratory of Dr. Philippe Séguéla at the MNI. His/Her work will be focused on the molecular physiology of neuronal ion channels (ex. ASIC, P2X, TRP, Piezo2) and their roles in pathological excitability in pain circuits. He/She will design the necessary experimental protocols, including, but not restricted to, strategies for the identification of selective antagonists and for the characterization of their pharmacological properties on specific sensory channels expressed in mammalian cell lines, primary neurons in culture or brain slices using patch clamp electrophysiological and cellular imaging approaches. It will also be his/her responsibility to initiate the development of a fluorescence-based voltage sensing assay in mammalian cells. Will analyze the data, write reports in due time, make presentations, participate to lab meetings and contribute to the writing of manuscripts and grant applications. When required, he/she will be involved in teaching and supervision of technical staff as well as trainees.

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Research Associate (Neural Circuits under Dr. Christopher C. Pack)

Primary duties:
The candidate will work independently on basic research projects in the laboratory of Dr. Pack at the MNI. His/her work will be focused on understanding the effects of non-invasive brain stimulation on neural activity in the primate brain, using multi-channel electrophysiological recordings. Additionally, he/she will devise models that relate the observed neurophysiological effects to behavioral effects associated with sensation, memory, learning, and motor control. He/she will design the necessary research methodology and perform the relevant data analyses. He/she will work with collaborative teams on the multidisciplinary aspects of the research projects and will further model the data, write drafts of manuscripts, and contribute to the writing of grants. The candidate will also participate in the supervision of full-time technician(s) and of graduate and summer trainees, if required.

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Research Assistant (Early Drug Discovery Unit under Dr. Thomas Durcan)

Primary duties:
The candidate selected will work in the Neuro’s Early Drug Discovery Unit under the supervision of Dr. Thomas Durcan focused on neuronal organoid and image analysis projects. Will be responsible for generating and characterizing neuronal organoid models derived from patient-derived induced pluripotent stem cells (iPSCs) as part of these projects. Tasks for these projects will include maintaining panels of iPSCs, following in house methods to generate 3D neuronal organoids across multiple projects, organoid fixations perfusions, tissue clearing, organoid staining, image acquisition and processing. Additional duties will include developing new software packages with support from other team members for analysis of the image datasets from the organoid sections and the intact 3D organoid, obtained through both confocal and light sheet microscopy.

The selected candidate will also assist with other organizational tasks within the lab, including overseeing inventories of cells and reagents needed for the different projects, for working with different members of the team in coordinating regular meetings. The selected candidate will also collect and interpret results from these research experiments that will be included in future publications. Along with these duties, will also be responsible for preparing reports and updating laboratory procedures on a regular basis, along with other related duties as assigned.

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Research Associate (Neuro Degenerative Disorders under Dr. Peter McPherson)

Primary duties:
As a research associate, the applicant will work independently on a research project in the laboratory of Dr. Peter McPherson. The aim of the project will be to characterize and assess the functional role of the protein DENND5A, which is the gene product mutated in a unique form of epileptic encephalopathy, a developmental neurological disease. The experimental techniques required to determine the function of DENND5A include but are not limited to live imaging fluorescence microscopy, molecular cloning, protein expression, primary cell cultures including hippocampal and neuronal cultures, antibody production and characterization, and lentiviral production. The individual will design and execute independently the experimental approaches necessary for the project. He/She will also analyze the data and contribute closely to the writing and publication of the scientific manuscripts.

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Research Associate (Neuro Degenerative Disorders under Dr. Alyson Fournier)

Primary duties:
The candidate will work independently on basic research projects in the laboratory of Dr. Alyson Fournier at the MNI. His/Her work will be focused on understanding how inflammation contributes to axon degeneration and regeneration with an emphasis on the understanding of the contribution of miRNA molecules. He/she will use a variety of cell biological and in vivo models to understand the contribution of miRNA molecules to optic nerve regeneration following axotomy and axon degeneration in the experimental autoimmune encephalomyelitis (EAE) animal model. He/she will design methodology and perform experiments, will work with collaborative teams on the multidisciplinary aspects of the research projects, and will further analyze the data, write drafts of manuscripts, and contribute to the writing of grants. The candidate will also participate in the supervision of full-time technician(s) and of undergraduate and graduate trainees when required.

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Research Associate (Neurodevelopmental Disorders Group under Dr. Xiaoqian Chai)

Primary duties:
The Research Associate will work independently and be responsible for leading experimental research projects in the Developmental Cognitive Neuroscience lab, under the supervision of Dr. Xiaoqian Chai. His/her work will include: (1) Lead a new research project which applies neuroimaging and genetic analyse on large open-source pediatric data biobanks, and (2) Lead the experimental research team to implement a multimodal imaging project on memory development in autism.

The research associate is expected to undertake lead authorship on scientific journals articles and technical reports, and contribute to preparation, review, and submission of grants. He/she will work with collaborative teams on the multidisciplinary aspects of the research projects. The candidate will also participate in the supervision of full-time technician(s) and of graduate and summer trainees, if required.

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Research Assistant (Bioinformatics under Dr. Ziv Gan-Or)

Specific duties include:

  • Design, build, and manage MySQL and CouchDB databases, including a Laboratory Information Management System (LIMS) database, for members of the PI laboratory and other projects/collaborators.
  • Develop and implement web-based interfaces (php, perl-CGI) of these databases, integrate user requirements in terms of on-line queries and analytical tools.
  • Setup and maintenance of a web server to host databases and their web interfaces
  • Reception and management of High-Throughput Sequencing (HTS) files. Assuring integrity, quality control, archiving, security and proper flow of incoming data.
  • Primary production of results for HTS projects of PI, other MNI labs and collaborators. Includes management of sufficient compute resources, checking results integrity and quality, generation of statistical reports, timely communicating analysis results to researchers.
  • Assist the supervisor, MNI lab members and collaborators for any of their specific HTS analytical needs: can take the form of developing scripts or software for specific needs, identifying and deploying existing software tools, or developing new analytical methods to meet project-specific needs.
  • Continuing development, implementation and expansion of HTS bioinformatics analysis pipelines. Continued development of existing tools; addition of new tools and analysis techniques and practices as they become available from the literature and the bioinformatics community at large.
  • Participate in bioinformatics meetings and contribute to the definition of priorities and future perspectives/orientations.

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Research Assistant (Bioinformatics under Dr. Ziv Gan-Or)

Specific duties include:

  • Reception and management of High‐Throughput Sequencing (HTS) files in a High-Performance Computing (HPC) environment. Assuring integrity, quality control, archiving, security and proper flow of incoming data.
  • Primary production of results for HTS projects of PI, other MNI labs and collaborators. Includes management of sufficient compute resources, checking results integrity and quality, generation of statistical reports, timely communicating analysis results to researchers.
  • Assistance to the PI and MNI lab members and collaborators for any of their specific HTS analytical needs: can take the form of developing scripts or software for specific needs, identifying and deploying existing software tools, or developing new analytical methods to meet project-specific needs.
  • Continuing development, implementation and expansion of HTS bioinformatics analysis pipelines.
  • Continued development of existing tools; addition of new tools and analysis techniques and practices as they become available from the literature and the bioinformatics community at large.
  • Participate in bioinformatics meetings and contribute to the definition of priorities and future perspectives/orientations.

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2nd Posting - Research Associate (Transforming Autism Care Consortium under Dr. Mayada Elsabbagh)

The Research Associate will work independently and be responsible for the data collected within Quebec 1000 (Q1K) project across a large network of centres, and handling the organization and dissemination of the data, under the supervision of Dr. Mayada Elsabbagh. The Research Associate will work closely with the project manager to design and fulfil the data platform scope of work and deliverables, requirements and resourcing, planning and roadmaps, progress tracking and reporting, and sustainable plans for technical maintenance and upkeep of the data platform, as well as backup and archiving. The Research Associate will be responsible for the technical security of the platform and ensuring all server operating system, dependency packages, and security practice (as defined in the governance framework [ethics approved]) upgrades are identified, planned, applied and maintained in a timely manner. The Research Associate is particularly responsible for establishing, tracking and auditing in the database both (a) the recording of consent (type, date, parties) and (b) all anonymization / encoding of data necessary for the project. Specific duties include:

  • Overseeing the development and maintenance of the multi‐centre research database, documentation plans, and administrative tools (including document repositories, issue‐tracking systems, mailing lists, and administrative shared documents, such as meeting notes, etc.).
  • Serving as the technical liaison between the project manager and the technical development and analytic teams.
  • Providing scientific advice and guidance to system developers and coordinators at remote sites across the consortium, regarding data organization and collection of behavioural and brain imaging battery of tests and instruments, genomic and biobanking data collection, neuroimaging and other data types.
  • Contribute to the definition of data and metadata stored for processed or derived results.
  • Maintaining, correcting and communicating any automated scoring and reporting of clinical assessments, in collaboration with analytics teams and in consultation with the project manager and scientific liaisons from the sites.
  • Planning, designing, implementing and reviewing data integrity audits on the data platform.
  • Establishing, documenting and tracking standard operating procedures across research sites.
  • Disseminating of data to collaborators and other organizations (in line with data access policies), preparing data releases and appropriate release documentation, and close collaboration with research principals and consortium personnel to ensure that all scientific and other objectives of the consortium will be met on time.

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Casual Research Assistant (Epilepsy Group under Dr. Birgit Frauscher)

Dr Birgit Frauscher’s Lab for Analytical Neurophysiology is seeking to hire a casual research assistant interested in neurophysiological research on mechanisms of sleep and epilepsy.

The successful candidate will work to further develop the human sleep intracranial EEG atlas (MNI Open iEEG Atlas) and related projects combining multimodal electrophysiology, neuropsychology, and neuroimaging data from a large‐scale international multicenter project supported by NSERC. He/she will be based at the MNI (Montreal, Quebec) and will work in a highly multidisciplinary environment (neurosciences, engineering, epileptology, and neuropsychology).

The candidate will have the opportunity to work in advanced electrophysiology studies in a clinical population (adults with drug-resistant epilepsy) by analyzing multimodal human data (intracranial and scalp EEG, MEG, memory tasks, and anatomical MRI). More specifically, she/he will be responsible for (1) coordinating data collection, data banking and establishing pipelines for data extraction, for (2) data analysis refining and developing software tools, and (3) assisting students of the lab in data analysis for their specific projects.

The successful candidate is expected to be responsible for the technical realization of experiments and analyze data independently with minimal supervision. He/she will analyze and prepare the data in final forms for presentation. He/she will also be required to prepare text and figures for manuscripts. He/she will thus be a contributing author to the resulting publications.

The position requires a strong background in project management, experience working with multiple collaborators at the same time, and assisting trainees. In addition to the research duties, he/she will also be required to help train new students and other personnel if the need arises, perform other related duties. Knowledge of neuroscience research is required. Knowledge and understanding of the research environment locally, nationally, and internationally are good assets.

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Medical Imaging Specialist (Academic Associate in McConnell Brain Imaging Centre)

The incumbent will work with the researchers who use the different image acquisition systems of the BIC, and help them in the development, implementation and the successful completion of their neuro imaging studies. The incumbent will develop image processing algorithms for analysis of medical images with applications in neuropsychology, neurology and neurosurgery used by hundreds of researchers, extending from within the NIST lab and the BIC to international collaborators. This will include the calibration, quality control, setup and basic troubleshooting of the different image processing software pipelines for the different imaging devices. Another important field of expertise to be covered is in quantitative analysis of structural MR data. The candidate will work in close collaboration with the BIC’s staff, supervising and advising the NIST lab’s software team, and graduate and summer trainees, if required. The applicant will interface between scientists, graduate students, research fellows, and clinicians to develop new methods of medical image analysis and to support the imaging research of members of the NIST lab and their collaborators (80% time) and support and maintain image processing tools and the MINC library used within the BIC (20% time). He/she will work with collaborative teams on the multidisciplinary aspects of the research projects and will further analyze the data, write drafts of manuscripts, and contribute to grant writing.

The position requires a strong background in project management, experience working with multiple collaborators at the same time, and assisting trainees. In addition to the research duties, he/she will also be required to help train new students and other personnel if the need arises, perform other related duties. Knowledge of neuroscience research is required. Knowledge and understanding of the research environment locally, nationally, and internationally are good assets.

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Research Associate (McConnell Brain Imaging Centre under Dr. Alain Dagher)

The candidate will work independently on brain imaging research projects in the laboratory of Dr. Alain Dagher at the MNI. His/her work will be focused on investigating, analyzing and modelling structural and functional brain imaging measures in controls, patients with Parkinson’s Disease (PD) and patients with Alzheimer’s disease (AD) using multiple measurement techniques, and clinical data. Will develop and establish a local expertise in multimodal neuroimaging analyses.

He/she will work with collaborative teams on the multidisciplinary aspects of the research projects and will further analyze the data, write drafts of manuscripts, and contribute to the writing of grants. The candidate will also participate in the supervision of graduate students and summer trainees, if required.

Applicants should be:

  • Experts in neuroscience: structural and functional MRI analysis, brain diseases, TMS, brain anatomy and connectivity, neuroimaging experimental design.
  • Advanced in: use of brain imaging software (SPM, FSL, ANTs, minctools), math/stats multivariate techniques such as PCA, ICA, PLS.
  • Advanced in use of Matlab or Python languages.

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Medical Writer and Project Developer (Academic Associate in Clinical Research Unit)

The Clinical Research Unit at the Montreal Neurological Institute in the Faculty of Medicine at McGill University invites applications for an Academic Associate position (Medical Writer and Project Developer).

Specific duties include:

  • Facilitate, coordinate, enhance and promote McGill’s research and development activities by working with investigators, academic researchers, granting agencies and industry partners to develop and write protocols for investigator initiated trials at the Clinical Research Unit at the MNI, in addition to writing grant proposals to fund them.
  • Develop and structure budgets for investigator initiated trials in the context of grant submission or request for other source of funding.
  • Ensure continuous support to investigators, physicians and industry partners, in the delivery of up-to-date activities and information, confirming priorities and timelines of project and grant opportunities and ensuring deadlines are met.
  • Ensure that grants and publications are developed and written in accordance with University and other parties, including sponsors, policies and procedures.
  • Communicate information to physicians, researchers, granting agencies and pharmaceutical companies on the proposals and publications that are generated by and through the CRU.
  • Prepare and submit documents required for approval or revision of investigator initiated study and trial protocols by the institutional ethics board
  • Create, edit and compile the documents required for submission to Health Canada, the FDA and other external regulatory authorities for approval of investigator initiated clinical trials, and carry out the submission process. This may include but is not limited to submissions in order to obtain no objection letters’ for phase 1-4 trials.
  • Provide training to new coordinators in the unit on issues pertaining to internally developed protocols as necessary.
  • Provide training/mentoring to new team members in the project development and medical writing core of the CRU
  • Participates in the development and maintenance of standard operating procedures as necessary.
  • Provide assistance in the research, writing, editing and submission of posters, publications, dossiers and presentations for clinicians and principal investigators associated with the clinical research unit.
  • Provide information and advice to researchers, project managers and coordinators on the preparation of investigator initiated trial proposals.
  • Liaison between researcher, clinical research unit and pharmaceutical companies as requested.
  • Liaison between members of the CBIGR team at the Clinical Research Unit, MNI Clinical Health Professionals and Academic Researchers to facilitate provision of biospecimens for pre-clinical research.
  • Assist in the development of local and national initiatives to facilitate pre-clinical and clinical research in neurological diseases.
  • Assist in the preparation of annual reports of the activities of the Clinical Research Unit, as necessary.
  • Assist in writing documents as required in conjunction with the development office for donor and other funding opportunities, as necessary.
  • Perform other administrative duties as required.
  • Attend national and international research conferences and meetings in order to network with key individuals required for project and trial development, and to remain current on research and trial design advances in key diseases areas for which projects and protocols are being developed.

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Research Associate (McConnell Brain Imaging Centre under Dr. Alexey Kostikov)

The candidate will work independently on basic research projects in the laboratory of Dr. Kostikov at the McConnell Brain Imaging Centre at the Neuro. His/her work will be focused on the development of radiochemical methods to incorporate positron-emitting isotope fluorine-18 into silicon-containing organic molecules designed for applications in positron emission tomography (PET). He/she will synthesize a library of organic compounds containing silicon-fluorine bonds, investigate their stability in physiological conditions and develop methods of radiolabeling the promising lead compounds with fluorine-18. It will also be his/her responsibility to assist with the evaluation of the radiolabeled tracers in animal models, including animal handling, tracer injections and data analysis.

He/she will work in a highly collaborative environment on the multidisciplinary projects and will coordinate the studies and contribute to the writing of manuscripts and grant applications. The candidate will also participate in the supervision of graduate and summer trainees, if required.

  • Experts in chemistry: multi-step organic synthesis, organic analytical methods, including NMR, HRMS, UV-Vis, HPLC and other applicable techniques.
  • Advanced in: PET radiochemistry with a focus on fluorine-18 labelled compounds.
  • Familiarity with: animal handling, PET acquisition and image data analysis.
  • Excellent written and verbal communication skills (English essential, French an asset).
  • Ability to mentor graduate students and summer trainees.
  • Ability to work in a multidisciplinary team environment.
  • Strong organization skills, attention to detail and priority setting skills.
  • Ability to work autonomously in a complex, changing, deadline-oriented environment.
  • Valid Workplace Hazardous Materials Information System (WHMIS) and Radiation Safety (RS) trainings.
  • Advanced knowledge of PET radiolabeling techniques.
  • Good knowledge of PET acquisition and data analysis principles.
  • Knowledge of good research practice.
  • A strong publication record in chemistry.

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Research Associate (Transforming Autism Care Consortium under Dr. Mayada Elsabbagh)

The Research Associate will work independently and be responsible for the data collected within Quebec 1000 (Q1K) project across a large network of centres, and handling the organization and dissemination of the data, under the supervision of Dr. Mayada Elsabbagh. The Research Associate will work closely with the project manager to design and fulfil the data platform scope of work and deliverables, requirements and resourcing, planning and roadmaps, progress tracking and reporting, and sustainable plans for technical maintenance and upkeep of the data platform, as well as backup and archiving. The Research Associate will be responsible for the technical security of the platform and ensuring all server operating system, dependency packages, and security practice (as defined in the governance framework [ethics approved]) upgrades are identified, planned, applied and maintained in a timely manner. The Research Associate is particularly responsible for establishing, tracking and auditing in the database both (a) the recording of consent (type, date, parties) and (b) all anonymization / encoding of data necessary for the project. Specific duties include:

  • Overseeing the development and maintenance of the multi-centre research database, documentation plans, and administrative tools (including document repositories, issue-tracking systems, mailing lists, and administrative shared documents, such as meeting notes, etc.).
  • Serving as the technical liaison between the project manager and the technical development and analytic teams.
  • Providing scientific advice and guidance to system developers and coordinators at remote sites across the consortium, regarding data organization and collection of behavioural and brain imaging battery of tests and instruments, genomic and biobanking data collection, neuroimaging and other data types.
  • Contribute to the definition of data and metadata stored for processed or derived results.
  • Maintaining, correcting and communicating any automated scoring and reporting of clinical assessments, in collaboration with analytics teams and in consultation with the project manager and scientific liaisons from the sites.
  • Planning, designing, implementing and reviewing data integrity audits on the data platform.
  • Establishing, documenting and tracking standard operating procedures across research sites.
  • Disseminating of data to collaborators and other organizations (in line with data access policies), preparing data releases and appropriate release documentation, and close collaboration with research principals and consortium personnel to ensure that all scientific and other objectives of the consortium will be met on time.

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Academic Associate (Junior Research Coordinator; 3 positions)

Specific duties include:

  • Facilitate, coordinate, enhance and promote McGill’s research and development activities by coordinating and managing clinical trial projects at the Clinical Research Unit at the MNI
  • Perform established clinical trial outcome measures including physical and cognitive assessments in numerous disease indications
  • Ensure continuous support to Investigators/Physicians in the delivery of up-to-date activities and information, confirming priorities and timeframes of clinical trial subjects. Read and understand clinical trial protocols. In conjunction with medical staff, oversee medication infusions, monitor and record patient symptoms, collect and transcribe laboratory data
  • Interpret information received on patients and select the most appropriate procedures and trials for performing the research and ethics administration activities. Ensure that the activities are performed in accordance with each individual clinical trial protocol and University and sponsors policies and procedures.
  • Communicate information to medical staff, patients and pharmaceutical companies on new information pertaining to patients, changes to regimens, deadlines in terms of tests to be performed (i.e., CT scan, blood tests, etc), regulatory information, etc.
  • Teach patients, researchers and nurses to follow protocol according to GCP guidelines.
  • Provide information and advice to researchers on the preparation of the research information.
  • Liaison between researcher, patient and pharmaceutical company. Attends all internal and external meetings as requested by the medical director and/or the pharmaceutical company for each clinical trial the coordinator is responsible for
  • Functions as a record-keeper in terms of patient information pertaining to the study and is accountable for the followup of business.
  • Oversee inventory of supplies needed for the clinical trial.
  • Perform other administrative duties as required.

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Research Associate (Brain Imaging Centre under Dr. Alain Dagher)

  • The candidate will work independently and be responsible for the research program in understanding the interplay of genetic risk and brain development, function and morphometry.
  • Curate, process, and analyze the following datasets of human MRI, genetics, and neurocognitive data: UK Biobank, ABCD, PING, HCP, using supercomputer resources from Compute Canada.
  • Generate polygenic risk scores for traits of interest including education, schizophrenia and autism and correlate them with morphometric measures from MRI including cortical thickness, neurite density, cortical myelin, diffusion tractography, and deformation based morphometry.
  • Develop machine learning algorithms to relate polygenic scores, life experiences, and brain anatomy.
  • Deposit all software code and imaging data to an open-access repository such as github.
  • Help supervise undergraduate and graduate students working in the Dagher lab.
  • Represent the lab in meetings, journal clubs, and conferences

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Research Assistant (Neural Circuits under Dr. Thomas Stroh)

The candidate will work on super-resolution microscopy/nanoscopy projects in the laboratory of Dr. Stroh and also provide this expertise to other researchers in the context of the Microscopic Cellular Imaging Facility as a shared research service. Within the research objectives set by the respective researcher, the successful candidate will plan and develop experiments using super-resolution microscopy techniques to achieve nanoscopic fluorescence imaging. He/she will autonomously provide support in the planning of projects, plan and execute staining protocols, perform super-resolution imaging and perform image analysis post-acquisition. If the opportunity arises, he/she will use their background knowledge and experience in super-resolution microscopy to independently resolve conceptual problems in the experiments and develop new technical and conceptual approaches.
Other qualifying skills and abilities:

  • Well-versed in advanced microscopy with minimum one year hands-on experience in the planning, execution and analysis of nanoscopy experiments.
  • Expertise in neuroscience, in particular in synaptic structure and the neuronal regulation of hormone secretion.
  • Advanced skills in sample preparation and image acquisition using nanoscopy techniques such as direct Stochastic Optical Reconstruction Microscopy (dSTORM) and Stimulated Emission Depletion (STED) Microscopy with good theoretical knowledge of other advanced microscopy techniques such as confocal and structured illumination microscopy.
  • Practical knowledge of the analysis of data sets acquired by dSTORM or STED and excellent knowledge of general image data analysis.
  • Excellent written and verbal communication skills (English essential, French an asset).
  • Strong organizational skills, attention to detail and priority setting skills.
  • Ability to work autonomously in a complex, changing, deadline-oriented environment.
  • Ability to guide other students and trainees.
  • Ability to work in a multidisciplinary team environment.
  • Knowledge of good research/laboratory practice.

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Research Assistant (Neurocognitive Aging under Dr. R. Nathan Spreng)

The position will support the PI in managing studies of neurocognitive aging involving neuropsychological and assessments. Projects include both cross-sectional and longitudinal investigations of neurocognitive and brain aging. Specific experiments will involve neuropsychological testing in young and older adults and include computer-based, remote, and in-lab neurocognitive measures. Drawing upon their training and experience in cognitive assessment and human participants research, and working under the supervision of the PI, this position will facilitate all aspects of various projects including experiment programming, recruitment, ethics, coordination of data collection, analysis, quality control and secure storage of neuroimaging and neurocognitive data.
In addition to these responsibilities the position will:

  1. Work with the PI and his senior project scientists to launch studies in LBC, including programming experiments using various software programs (e.g. Matlab, E-prime), developing automated scoring, data-base management and statistical analysis protocols (excel, R), as well as facilitating accurate translations of neuropsychological measures into French and English as necessary.
  2. Train students in the lab on the development, implementation, and scoring of all neuropsychological assessment measures (this will include training lab members on principles of neuropsychological assessment, with specific emphasis on neurocognitive aging assessments).
  3. Assist with data analysis and dissemination (including preparing publications for peer review) and prepare data summaries and methods for inclusion in grant submissions.
  4. Prepare comprehensive standard operating procedures (SOPs) for all aspects of the data collection protocols and ensure all personnel adhere to the procedures for each study.

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Research Assistant (Neural Circuits Unit (Complex Neural Systems) under Dr. Philippe Séguéla)

In this position, the candidate will assist in elucidating the molecular mechanisms of somatosensation through studying the normal and pathological physiology of primary somatosensory neurons in rodent models.

He/she will be assigned projects aimed at understanding how pain and itch transmission are discriminated both peripherally and centrally. He/she will actively participate in (1) live cell imaging studies and patch clamp recordings to monitor stimuli-evoked firing activities in DRG/TG neurons; (2) the study of molecular mechanisms by which nociceptive and pruriceptive transductions are regulated in different pathologies; (3) elucidating the specific mechanisms of pruritogen-induced and neurogenic inflammation.

He/she will independently (i) refine the technique of live cell imaging combined with electrophysiology; (ii) design experiments to identify several receptors and ion channels involved in nociception and pruriception; (iii) use innovatively transgenic mouse lines and targeted AAV-mediated gene delivery according to published procedures.

He/she will be responsible for the design, development and fine tuning of the experimental design to evaluate the consequences of various experimental manipulations. He/she will carry out statistical analysis of the data and actively participate in the design and execution of further studies towards the set goals.

He/she will design and execute experiments and analyze data independently with minimal supervision. He/she will analyze and prepare the data for formal presentation. He/she will also be required to prepare text and publication-quality figures for manuscripts and will thus be a first author or co-author in the resulting publications depending on his/her contribution.

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Research Associate (Bouchard Intellectual Disabilities platform under Dr. Edward Fon)

The candidate will work independently and be responsible for leading and coordinating immunohistochemistry projects related to work with tissue samples from neuronal organoids for projects related to intellectual disabilities and other neurodevelopmental disorders. Duties will include working with team members in the ID platform and within other groups including the MNI tissue platform on a number of discovery projects, liaising with program directors within the MNI and implementing and developing new techniques to process, embed, section, stain, and image tissue samples from neuronal organoid and other tissue related to the study of brain disorders. The applicant will work with other groups to identify their needs, and to create new SOPS for obtaining, staining and analyzing new tissue section.

The successful applicant will:

  • Establish protocols for tissue processing, embedding and sectioning different tissue samples using both a microtome and/or a cryostat.
  • Develop new SOPs for staining, imaging and analyzing tissue samples.
  • Independently carry out projects to completion.
  • Write and edit SOPs, scientific reports, and participate in the writing of research applications as part of this project.
  • Assist other lab members and trainees with aspects of projects related to histology, tissue sectioning and immunocytochemistry including immunofluorescence and immunohistochemistry.
  • Oversee the maintenance of equipment within the platform and train other users on the appropriate use of sectioning and histology equipment.
  • Prepare and present reports and technical presentations to internal and external scientific groups.
  • Other related duties as assigned.

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Research Associate (Brain Tumour Research Centre under Dr. Kevin Petrecca)

The Research Associate will be responsible for leading software development projects and the successful completion of research projects.

  • Contribute substantially to planning new innovative bioinformatics projects7T.
  • Lead all aspects of software evaluation and development within the bioinformatics platform.
  • Use the bioinformatics platform to analyze bulk and single-cell sequencing data (RNA, DNA, ATAC) from brain cancers and brain tumors.
  • Work with collaborative teams on the multidisciplinary aspects of the research projects.
  • Provide guidance to students on the platform and incorporate the tools they develop as appropriate.
  • Contribute substantially to the planning of new innovative bioinformatics projects through contributing to grant writing.

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Research Associate (Neurodegenerative Disorders under Dr. Edward Fon)

The candidate will work independently on basic research projects in the laboratory of Dr. Fon at the MNI. The candidate will be responsible for conducting and directing mouse research projects.

The candidate will conduct research on Parkinson disease’s risk genes using BioID assays and Crispr/Cas9 screens. The candidate will also validate promising hits in iPSC-derived cell models as well as in mouse models of Parkinson disease.

He/she will establish research methods, design protocols and review and evaluate research findings.

He/she will work with collaborative teams on the multidisciplinary aspects of the research projects and will further analyze the data, write manuscripts and contribute to the writing of grants. The candidate will also participate in the supervision of full-time technician(s) and of graduate and summer trainees, if required.

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Research Associate (Brain Imaging Centre under Dr. Richard Hoge)

The candidate will work independently on research and development projects in the new 7 tesla MRI facility operated by the BIC MRI Unit (MRU). The candidate's work will focus on developing radiofrequency coils to exploit the various capabilities of the 7T MRI. This will include coils for applications including parallel transmit, high-resolution functional and structural MRI, multinuclear spectroscopy, and arterial spin-labeling. The candidate will collaborate with other members of the MRI Unit in the integration of these coils with the 7T scanner, and the development of applications for the study of various neurological conditions such as Parkinson's disease, multiple sclerosis, and autism spectrum disorder. The candidate will design the necessary methodology and fabrication capabilities required to carry out the above mandate, working collaboratively with multi-disciplinary research teams in tasks to include the interpretation of data, preparation of manuscripts, and preparation of grant submissions. The candidate will also be called upon to help supervise full-time technicians, research assistants, and trainees at the graduate and undergraduate levels.

The successful applicant will have access to an RF laboratory equipped with the necessary instrumentation, a machine shop including CNC equipment, and three MRI systems (a Siemens Terra 7T, Siemens Prisma 3T, and Bruker Pharmascan 7T).

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Research Associate (Neurodegenerative Diseases Unit under Dr. Guy Rouleau)

The candidate will work independently on basic research projects in the laboratory of Dr. Rouleau at the MNI. His/Her work will be focused on the preparation and characterization of iPSC-derived cells models (e.g. motor neurons and astrocytes) that are relevant to amyotrophic lateral sclerosis (ALS). These ALS relevant cells will be derived from biological material (e.g. peripheral blood mononuclear cell or primary fibroblasts) obtained from patients established to present key genetic risk factors.

He/She will characterize these cells through examinations of their physiological properties, profiling of cell specific markers, electrophysiological measurements, muscle innervation assays and analysis of secretomes.

He/she will work with collaborative teams on the multidisciplinary aspects of the research projects and will further analyze the data, write drafts of manuscripts, and contribute to the writing of grants. The candidate will work closely with full-time technician(s), graduate and postdoctoral trainees, and help to guide their effort if required.

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Research Assistant (McConnell Brain Imaging Centre under Dr. Alain Dagher)

To use large datasets such as the UK Biobank, Human Connectome Project, Parkinson Progression Markers Initiative, etc… to answer questions about the role of genetics, brain anatomy and function in vulnerability to neurological or psychiatric illness. These large-scale datasets include multimodal neuroimaging, genetics, cognitive and health and personality questionnaire information. The candidate will develop new research questions and computer pipelines in association with other lab members and the two PIs.
Primary duties:

  • Plan and develop projects that depend on processing of large neuroimaging datasets to answer questions about brain endophenotypes of mental illness.
  • Develop research protocols in neuroimaging, genetics and psychology under the guidance of the PIs.
  • Develop docker-based computer pipelines for automated image processing and quality control.
  • Pipelines to include anatomical processing (cortical thickness, deformation-based morphometry, tractography), functional MRI (BOLD imaging at rest and during tasks), genetics analysis (e.g. polygenic risk scores, Mendelian randomization).
  • Run the lab’s local and cloud-based computing infrastructure.
  • Interface with local members of the C-Brain consortium.
  • Maintain data and programs on Compute Canada.
  • Assist students in analysis of brain imaging data.
  • Attend weekly lab meetings.

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Academic Associate (Open Science Alliance Officer)

The Academic Associate will lead all activities related to the creation of a nation-wide coalition of Open science entities in neuroscience: plan and oversee the development and implementation of incentivization mechanisms, develop outreach strategies to potential early-adopters of Open Science in Canada in the field of neuroscience and beyond, build robust collaborations with these various partners across the country by ensuring their compliance to TOSI Guiding Principles, act as liaison person across Canada and beyond.
Specific duties include:

  • Set up Business Intelligence on major neuroscience institutes across the country and build a roadmap/strategy to engage them
  • Pursue discussions with initial partners and close collaborators in the neuroscience field in Canada, and translate these into concrete collaboration agreements
  • Participate in the development of the right narrative to incentivize these potential early-adopters of Open Science and Neuro’s guiding principles
  • Support potential early-adopter entities in the implementation of OS policies by spending time locally to understand the institutional culture, share best practices and lessons learned from The Neuro.
  • Develop tools and strategies to share lessons learnt and best practices from The Neuro’s experiment for the implementation of OS practice
  • Finalize the implementation of the National Open Science Incentive Fund and its Allocation Committee
  • Develop and implement clear and comprehensive guidelines on compliance to TOSI Guiding Principles
  • Generate, maintain and implement a collaborative framework and policy/procedure documents based on the principles of Open Science, including MOUs and various contracts
  • Plan and coordinate the organization of workshops and events contributing to raising awareness on Open Science practice at The Neuro and engaging more partners to adopt OS practices
  • Plan and coordinate one annual meeting gathering all existing and potential TOSI partners in Canada
  • Develop a comprehensive strategy to engage international partners in neuroscience
  • Contribute or lead publication of articles on the implementation of OS practices and any other OS-related subjects
  • Ensure thorough knowledge transfer activities through the preparation of various tools, methodologies, processes etc.

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Research Assistant (Brain Imaging Centre, NeuroImaging and Surgical Technologies Laboratory under Dr. Louis Collins)

He/she will interface between scientists, graduate students, research fellows, clinicians and patients. In addition to assisting in lab management, the applicant will work closely with the NIST team in projects related to image guided surgery in the laboratory and the operating room as well as working with patients to bring them for MRI scanning. The applicant will become a key resource person for the NIST lab, becoming a (power) user of our IBIS surgical navigation system and provide continuity over time (as students and fellows come and go) in dealing with the clinicians and the OR staff.
Specific duties include:

  • Develop standard operating procedures to bring the IBIS navigation software into the operating room, to work with the surgeons and OR staff and to assist the students to test their specific tools and gather data in surgery.
  • Assist in the design, development and fine-tuning of experimental design with the PI, graduate students and clinical fellows.
  • Assist with data acquisition and analysis and actively participate in the design and execution of further studies towards the goals of the NIST lab.
  • Assist with design, execute experiments, and analyze data with minimal supervision. He/she will analyze and prepare the data in final forms for presentation. He/she will also be required to prepare text and figures for manuscripts.
  • Train new students and other personnel if the need arises.
  • Keep abreast of the changes introduced by the funding agencies. He/she will help with grant writing, preparing budgets, documentation, preparing figures and appendices as needed. He/she will prepare progress reports as needed.
  • Prepare ethics submissions for different research projects in the NIST lab under the direction of the PI. The candidate will manage deadlines for applications/renewals with the MNI REB, maintain data for renewals (numbers of patients, papers, etc…), to prepare and submit ethics renewals.

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Research Associate (MNI iPSC platform, under Dr. Thomas Durcan)

The candidate will work independently and be responsible for leading and coordinating multiple drug discovery projects related to work with induced pluripotent stem cells (iPSCs) and generating oligodendrocytes and astrocytes from these iPSCs for discovery-based projects. Duties will include working with team members in the platform and within other groups, liaising with program directors within the MNI and implementing and developing new SOPs to generate and characterize oligodendrocytes, astrocytes and other glial cells generated from different patient lines. The applicant will work to create new SOPS for obtaining, staining and analyzing these cell types.
The successful applicant will:

  • Establish protocols for generating and characterizing oligodendrocytes and other glial cells from iPSCs.
  • Develop new SOPs for staining, imaging and analyzing cell types generated.
  • Independently carry out projects to completion.
  • Write and edit SOPs, scientific reports, and participate in the writing of research applications as part of this project
  • Assist other lab members and trainees with aspects of projects related to assay development and discovery.
  • Prepare and present reports and technical presentations to internal and external scientific groups.
  • Other related duties as assigned.

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Research Assistant (McConnell Brain Imaging Centre, under Dr. Alain Dagher)

To use large datasets such as the UK Biobank, Human Connectome Project, Parkinson Progression Markers Initiative, etc… to answer questions about the role of genetics, brain anatomy and function in vulnerability to neurological or psychiatric illness. These large-scale datasets include multimodal neuroimaging, genetics, cognitive and health and personality questionnaire information. The candidate will develop new research questions and computer pipelines in association with other lab members and the two PIs.
Primary duties:

  • Plan and develop projects that depend on processing of large neuroimaging datasets to answer questions about brain endophenotypes of mental illness.
  • Develop research protocols in neuroimaging, genetics and psychology under the guidance of the PIs.
  • Develop docker-based computer pipelines for automated image processing and quality control.
  • Pipelines to include anatomical processing (cortical thickness, deformation-based morphometry, tractography), functional MRI (BOLD imaging at rest and during tasks), genetics analysis (e.g. polygenic risk scores, Mendelian randomization).
  • Run the lab’s local and cloud-based computing infrastructure.
  • Interface with local members of the C-Brain consortium.
  • Maintain data and programs on Compute Canada.
  • Assist students in analysis of brain imaging data.
  • Attend weekly lab meetings.

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Research Assistant - NeuroPM lab (Under Dr. Yasser Iturria Medina)

We are looking to hire a research assistant to provide support to the supervisor for multiple ongoing research projects.

The research assistant will be involved in research aimed at understanding the multifactorial mechanisms underlying neurodegenerative disorders and the identification of effective therapeutic interventions. She/he will be responsible for analyzing multimodal brain imaging data (PET, MRI) and extending and applying specific computational methods developed in the lab. The analyzes will include the preprocessing of large-scale multimodal datasets, and the implementation, application, and validation of advanced computational/statistical techniques. She/he will work directly with the supervisor, overseeing and maintaining data analysis pipelines, in conjunction with graduate students and postdoctoral fellows. The RA will also participate in the preparation and publication of scientific articles associated with the results obtained in the lab.

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Junior Research Coordinator - Clinical Research Unit (4 positions)

The Clinical Research Unit at the Montreal Neurological Institute in the Faculty of Medicine at McGill University invites applications for an Academic Associate.
Specific duties include:

  • Facilitate, coordinate, enhance and promote McGill’s research and development activities by coordinating and managing clinical trial projects at the Clinical Research Unit at the MNI
  • Perform established clinical trial outcome measures including physical and cognitive assessments in numerous disease indications
  • Ensure continuous support to Investigators/Physicians in the delivery of up-to-date activities and information, confirming priorities and timeframes of clinical trial subjects. Read and understand clinical trial protocols. In conjunction with medical staff, oversee medication infusions, monitor and record patient symptoms, collect and transcribe laboratory data
  • Interpret information received on patients and select the most appropriate procedures and trials for performing the research and ethics administration activities. Ensure that the activities are performed in accordance with each individual clinical trial protocol and University and sponsors policies and procedures.
  • Communicate information to medical staff, patients and pharmaceutical companies on new information pertaining to patients, changes to regimens, deadlines in terms of tests to be performed (i.e., CT scan, blood tests, etc), regulatory information, etc.
  • Teach patients, researchers and nurses to follow protocol according to GCP guidelines.
  • Provide information and advice to researchers on the preparation of the research information.
  • Liaison between researcher, patient and pharmaceutical company. Attends all internal and external meetings as requested by the medical director and/or the pharmaceutical company for each clinical trial the coordinator is responsible for
  • Functions as a record-keeper in terms of patient information pertaining to the study and is accountable for the followup of business.
  • Oversee inventory of supplies needed for the clinical trial.

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Research Assistant – McConnell Brain Imaging Centre – Montreal Neurological Institute (Under Dr. Julien Doyon)

We are looking to hire a research assistant to provide support to the supervisor for all ongoing research projects . Assist graduate students and postdoctoral fellows in carrying out behavioral and neuroimaging studies in cognitive neuroscience, and motor learning in particular. Develop, oversee and maintain data analysis pipelines in conjunction with graduate students and postdoctoral fellows. Supervise undergraduate students as well as casuals.

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Research Assistant – Laboratory for Applied Innovations in Neurocognitive Disorders (Under Dr. Simon Ducharme)

Dr. Simon Ducharme’s laboratory is looking for a research assistant to manage and implement several neuroimaging research projects on frontotemporal dementia and Alzheimer’s disease. Current funded projects focus on the discovery and clinical implementation of novel brain MRI and PET scans biomarkers for the early diagnosis of these neurocognitive disorders.
Specific duties include:

  • Conduct patient research visits including retrieving clinical information, organize scanning sessions and perform basic cognitive tests.
  • Meeting selected patients during the neurocognitive clinic to obtain consent for studies and contact information.
  • Assist the PI with ethics board application and periodic reviews.
  • Organize collected data in a cloud based system.
  • Perform imaging analyses and statistics
  • Assist the PI with grant applications and manuscript preparation.
  • Assist with the interactions between the PI and graduate students.
  • Improve online presence and communication for the lab (e.g., website, social media).

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The Neuro is a McGill research and teaching institute; delivering high quality patient care, as part of the Neuroscience Mission of the McGill University Health Centre. We are proud to be a Killam Institution, supported by the Killam Trusts.

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