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The laboratory of Samantha Gruenheid (Department of Microbiology/Immunology) studies the pathogenesis and host response to infection with enterohemorrhagic and enteropathogenic Escherichia coli (EHEC/EPEC), a group of water and food-borne Gram-negative bacteria responsible for acute cases of diarrheal disease with potentially fatal complications. The lab studies inbred mouse strains that are either resistant or susceptible to infection with the mouse pathogen Citrobacter rodentium, a model of human infections with EHEC/EPEC. The lab uses a genetic approach to identify the genes and proteins controlling inflammatory response at the intestinal mucosa, and susceptibility to lethal infection. On the pathogen side, the laboratory studies a group of EHEC and EPEC proteins that are injected into host intestinal epithelial cells by the bacterial by Type III secretion system to interfere with host functions leading to disease. |
Job opening for a postdoctoral fellow
The Trudeau (University of Montreal) and Gruenheid (McGill) labs in Montreal presently have a job opening for a postdoctoral fellow to work on a project linking bacterial infection to immunity and Parkinson's disease, taking advantage of mouse models. The ideal applicant will have expertise in neuroscience and immunology including in one or more of the following techniques: primary neuronal cultures, neuroanatomy, behavioral analyses, electrophysiology, fluorescence imaging, flow cytometry. Applicants should also have experience working with mice. Interested applicants should send a CV and statement explaining their previous training and motivation for this job to Dr. Louis-Eric Trudeau (louis-eric.trudeau@umontreal) and put Dr. Samantha Gruenheid in copy (samantha.gruenheid [at] mcgill.ca), and with the subject line “Application for PDF position”. The position is for 3 to 5 years and the salary will be determined based on previous expertise.
Interested applicants can find out more about the project here: https://rdcu.be/bKIWo and about the two labs by consulting the following web sites: www.trudeaulab.org and www.mcgill.ca/mrcct/members/primary-members/samantha-gruenheid.
Gruenheid Lab Contact Information |
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