Sabrina Côté-Maldonado

Name: Sabrina Côté-Maldonado

Most recent degree: BSc Physics - Université de Montréal

Level at MPU: MSc

Email: sabrina.cotemaldonado [at]

Supervisor(s): Horacio Jose Patronicio

Research interests: Interfractional prostate motion in external beam radiation therapy (EBRT)

Research summary

Prostate cancer is the most commonly diagnosed cancer among Canadian men, excluding non-melanoma skin cancer. Most often, it is treated using radiotherapy such as with external beam radiation therapy (EBRT). Because EBRT uses external radiation, chances of underdosing moving tumors are increased. This is notably the case for prostate tumors as they are subject to motion because of their location in the pelvic area. Fortunately, image-guided radiation therapy (IGRT) along with a larger PTV margin helps ensuring a good tumor control. However, over time, there has been an increase use of hypofractionated EBRT treatments for prostate cases, implying a reduction of the PTV margins to minimize normal tissues complications. The issue is that the prostate motion remains unchanged. Is it therefore safe or appropriate to decrease the PTV margin regardless of the patient treated? Or could only some patients benefit from a customized margin without a decrease in treatment efficiency? My master project attempts to answer those questions.

Key publications



Fonds de recherche du Québec - Nature et Technologies (FRQNT) (2019 - 2021)

Fonds de recherche du Québec - Santé (FRQS) (2019)

Ervin B. Podgorsak Fellowship - McGill University Medical Physics Unit (2019)

Hats Off to you! - Excellence in Science segment (2019)


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