Jessica Perez

Name: Jessica Perez, MSc

Level at MPU: PhD

Email: jessica.perez2 [at] mail.mcgill.ca

Supervisor(s): Dr. Issam El Naqa and Dr. Jay Nadeau

Research interests: Biomedical Engineering, Imaging

 

Research summary

Radiation-induced lung damage (RILD) is very common in patients treated for lung cancer and is a limiting factor for increasing the dose to achieve better tumour control. Mesenchymal stem cells (MSCs) have demonstrated promises in mitigating inflammation and fibrosis but their mechanism of action is still not fully understood. In this work we are developing a molecular imaging platform to track and monitor stem cells behaviour in vivo to uncover their potential in the context of RILD.

 

Key publications

  1. Perez, J. et al. Tracking of mesenchymal stem cells with fluorescence endomicroscopy imaging in radiotherapy-induced lung injury. Sci. Rep. 7, 13087 (2017).
  2. Perez J, Ybarra N, Chagnon F, Lesur O, El Naqa I. Quantitative image analysis of fluorescence endomicroscopy for mesenchymal stem cells tracking in the lung. Oral presentation at: International Union for Physical and Engineering Sciences in Medicine (IUPESM) World Congress on Medical Physics and Biomedical Engineering; June 7th-12th 2015; Toronto, ON, Canada
  3. Perez J, Vallières M, Ybarra N, Maria O, Chagnon F, Lesur O, El Naqa I. Fluorescence endomicroscopy as a tool to assess radiation-induced lung damage, protection and regeneration. Poster presented at: American Society for Radiation Oncology (ASTRO) 56th annual meeting; September 14th-17th 2014; San Francisco, CA, USA
  4. Perez J, Ybarra N, Maria O, Chagnon F, Lesur O, El Naqa I. In vivo fluorescence imaging and endomicroscopy for tracking of mesenchymal stem cells in post-radiotherapy lung injury rat model. Poster presented at: International Society for Stem Cell Research (ISSCR) 12th annual meeting; June 18th-21st 2014; Vancouver, BC, Canada

 

Awards

NSERC-CREATE in Integrated Sensor Systems

NSERC-CREATE Medical Physics Research Training Network

 

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