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A step closer to identifying cause of a blinding disease

Researchers find clue to rare genetic disorder

Leber hereditary optic neuropathy (LHON) is an inherited form of vision loss that causes people to have trouble with their colour vision and difficulty seeing in the centre of their visual field. Due to the founder effect from the filles du roi, there is a disproportionate preponderance of a particular LHON mutation among the French-Canadian population.

Published: 22 May 2019

A step toward better understanding brain anatomy of autism spectrum disorder

Study could lead to development of personalized biomarkers and treatment

Individuals with autism spectrum disorder (ASD) are often lumped into a single catch-all group, despite significant differences in symptom profile and severity. Further muddying the waters when trying to understand and treat ASD, many previous studies show significant variability in findings.

Published: 8 May 2019

Brain signaling proteins hit the road running

New study of brain neurotransmitter receptor has implications for drug discovery

Surprisingly complex movements in an important neurotransmitter receptor may help explain the brain’s unpredictable response to drugs, according to a new study. New research from an international team, published this week in the journal Neuron, has revealed that the resting state of signaling proteins are much more dynamic than previously thought.

Published: 30 Apr 2019

Dr. Shari Baum on the Faculty’s Strategic Research Plan

McGill University’s Faculty of Medicine unveiled a new strategic research plan (SRP) for the Faculty in 2014, which was subsequently updated in 2017 as part of the strategic planning exercise known as Project Renaissance. Dr. Shari Baum, who recently assumed the role of Vice-Dean, Life Sciences, played an important role in the development of the most recent version of the plan. Dr.

Published: 26 Apr 2019

I Medici di McGill celebrating 30 years of concerts for causes

Growing up in the Croatian capital city of Zagreb, Dr. Ante L. Padjen, Associate Professor (post- retirement) at McGill University, found inspiration in the orchestra of the Croatian Institute of Music (CIM). Founded in 1827, the CIM has mostly been an ensemble comprised of physicians, lawyers, engineers and students, conducted by a professor from the Zagreb Music Academy. Following an opportunity to play briefly with CIM himself, Dr.

Published: 26 Apr 2019

Deanna MacNeil from the Autexier lab establishes how an imbalance favoring telomerase RNA degradation over correct maturation is causative for the premature aging telomere biology disorder dyskeratosis congenita.

The telomerase holoenzyme responsible for maintaining telomeres in vertebrates requires many components in vivo, including dyskerin. Dyskerin binds and regulates the accumulation of the human telomerase RNA, hTR, as well as other non-coding RNAs that share the conserved H/ACA box motif.

Published: 23 Apr 2019

New PhD program in Quantitative Life Sciences approved

By Gillian Woodford

An innovative interdisciplinary PhD program will bridge the gap between the quantitative and biological domains to improve life sciences research.

Published: 18 Apr 2019

Anti-inflammatory drugs ineffective for prevention of Alzheimer’s disease

Study sheds light on longstanding debate

 

Published: 5 Apr 2019

Predicting Breast Cancer Metastasis to the Lung and Liver with Biomarkers

By Josh Kaiser

For about 20% to 30% of breast cancer patients, their primary tumour will spread to other organs such as the bones, lungs, liver, or brain. Remarkably, this metastasis to other organs accounts for 90% of deaths during breast cancer treatment. Unfortunately, many of the specific cellular processes regulating breast cancer metastasis are poorly understood and there are currently no targeted treatments.

Published: 4 Apr 2019

McGill approves new Institute of Health Sciences Education

By Matthew Brett

McGill University is now home to a new Institute of Health Sciences Education thanks to a motion approved by its Board of Governors in February.

The Institute, which replaces the existing Centre for Medical Education, is now an academic hiring and teaching unit that can provide graduate programs in health sciences education.

Published: 1 Apr 2019

Student-led events aim to raise awareness of speech-language pathology issues

Students from the McGill University Faculty of Medicine’s School of Communication Sciences and Disorders (SCSD) have once again been busy organizing a series of events for spring 2019. Working under the guidance of Dr.

Published: 1 Apr 2019

Four Burning Questions for Madhukar Pai & Dick Menzies on World TB Day

March 24th is World TB Day. Tuberculosis (TB) is an ancient disease that killed humans as far back as 600 BC. Sadly, even in 2019, it is the leading infectious killer of humanity.

Published: 21 Mar 2019

Neuro researchers receive early-career grants

Adrien Peyrache and Stuart Trenholm will study epilepsy and vision

Published: 11 Mar 2019

Using sleep disorder to predict Parkinson’s disease

Large international study will help select and categorize patients for better clinical trials

A large multi-centre study of more than 1,200 patients provides important predictors of Parkinson’s disease progression, which will allow better candidate selection for clinical trials and more effective therapy development.

Published: 4 Mar 2019

Talking women’s health with Dr. Gabrielle Cassir

A native Montrealer, Dr. Gabrielle Cassir completed her medical school and residency training at Université de Montreal. During her time as a medical student, she was also able to experience the American health care system, spending two months at Jackson Memorial Hospital in Miami.

Published: 1 Mar 2019

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