BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20260530T233710EDT-0250wRxV6v@132.216.98.100 DTSTAMP:20260531T033710Z DESCRIPTION:\nSupported by the generosity of the Killam Trusts\, The Neuro' s Killam Seminar Series invites outstanding guest speakers whose research is of interest to the scientific community at The Neuro and McGill Univers ity.\n\n\nRegister Now\n\nTo watch online\, click here\n\nHost: Massimo Av oli\n\n\nThe role of BDNF in hormonal regulation of seizures in temporal l obe epilepsy\n\nAbstract: One of the long-standing questions in epilepsy r esearch is why seizures are so sensitive to the influence of gonadal hormo nes. In this seminar\, data will be presented to support the novel hypothe sis that steroid receptors acting on their target genes provide an explana tion\, and focus on the gene for brain-derived neurotrophic factor\, a neu rotrophin known for its influence on neurodevelopment and the mature brain . The results shed light not only on epilepsy but also many aspects of nor mal function and diverse neurological and psychiatric disorders.\n\nHelen Scharfman\n\nCenter for Dementia Research\n\nDr. Helen Scharfman completed her doctoral training in the Department of Pharmacology at the Uniformed Services University of the Health Sciences in Bethesda\, Maryland and her postdoctoral training in the Department of Neurological Surgery at the Uni versity of Washington in Seattle\, Washington. She was a Research Associat e in the Department of Neurobiology and Behavior at the State University o f Stony Brook before starting her own laboratory at Helen Hayes Hospital a nd Columbia University in 1991. In 2007\, she moved her laboratory to the Nathan Kline Institute\, and her primary appointment was moved to New York University Grossman School of Medicine\, where she is Professor of Child & Adolescent Psychiatry\, Psychiatry\, and Physiology & Neuroscience.\n\nD r. Scharfman’s primary research interests include the mechanisms underlyin g neuronal excitability and neuronal plasticity\, neuroendocrinology\, and neurogenesis. The emphasis of the laboratory is to understand the basic m echanisms of normal function in order to better address dysfunction — i.e. \, in neurological disorders and psychiatric illness. An area of long-stan ding interest has been the hippocampus and adjacent brain regions\, so the re has been an emphasis on learning disorders\, as well as epilepsy.\n\nDr . Scharfman has contributed broadly in basic and translational neuroscienc e. She has served on numerous advisory boards for national and internation al organizations\, such as the American Epilepsy Society\, the Epilepsy Fo undation\, Citizens United for Research on Epilepsy\, and Parents Against Childhood Epilepsy. She has also served as a reviewer for NIH\, NSF\, and many international funding organizations. She has been continuously R01-fu nded by NIH since starting her laboratory. She has served on the editorial boards of Epilepsia and Epilepsy Research\, and is currently on the edito rial boards of Epilepsy and Behavior\, Open Access Endocrinology\, Frontie rs in Neuroscience – Neurogenesis\, Brain Structure & Function\, and Epile psy Research & Treatment\, and reviews ad hoc for over 40 neuroscience jou rnals. She was named the NYS Department of Health Employee of the Year in 2006 for establishing a research center at Helen Hayes Hospital to promote translational research. She has published over 100 articles and edited or co-edited 5 books.\n DTSTART:20260609T200000Z DTEND:20260609T210000Z LOCATION:de Grandpre Communications Centre\, The Neuro\, Montreal Neurologi cal Institute\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue University SUMMARY:Killam Seminar Series: The role of BDNF in hormonal regulation of s eizures in temporal lobe epilepsy URL:https://www.mcgill.ca/medhealthsci-gradstudies/channels/event/killam-se minar-series-role-bdnf-hormonal-regulation-seizures-temporal-lobe-epilepsy -372041 END:VEVENT END:VCALENDAR