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UID:20260906T025101EDT-1213mD3xsI@132.216.98.100
DTSTAMP:20260906T065101Z
DESCRIPTION:Title: The MeshCODE theory – does our brain store memories in a
  binary format?\n\nAbstract: Cell adhesion to the extracellular matrix (EC
 M)\, mediated by integrins\, is exquisitely sensitive to biochemical\, str
 uctural\, and mechanical features of the ECM. Talin\, the primary link bet
 ween integrins and the actin cytoskeleton\, coordinates the binding of a w
 ide range of cytoskeletal and signaling adaptors in a force-dependent mann
 er. Our work has defined talin as a major mechanosensitive signalling hub.
  More recently we have discovered that talin has “molecular memory” and so
  provides organisms with a way to store data\, through persistent alterati
 ons in protein conformation. In this talk I discuss the implications of th
 ese findings and describe a novel role for integrin adhesions in data-stor
 age leading to a novel theory of how memories are stored in our brain. The
  MeshCODE theory presented here provides an original concept for the molec
 ular basis of memory storage. I propose that memory is biochemical in natu
 re\, written in the form of different protein conformations in each of the
  trillions of synapses. Based on established biophysical principles\, a me
 chanical basis for memory would provide a physical location for data stora
 ge in the brain. Furthermore\, the conversion and storage of sensory and t
 emporal inputs into a binary format identifies an addressable read/write m
 emory system supporting the view of the mind as an organic supercomputer.
 \n\nWeb site : https://www.mcgill.ca/qls/seminars\n\nSeminar CAMBAM Semina
 r Series\n	En ligne/Web - https://mcgill.zoom.us/j/85428056343\n\n \n
DTSTART:20211130T170000Z
DTEND:20211130T180000Z
SUMMARY:Ben Goult (University of Kent)
URL:https://www.mcgill.ca/mathstat/channels/event/ben-goult-university-kent
 -335170
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