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UID:20261101T214543EST-2939i82gCt@132.216.98.100
DTSTAMP:20261102T024543Z
DESCRIPTION:Progress in Understanding the Molecular Oxygen Paradox: Definin
 g how mitochondria generate hydrogen peroxide for cell signaling and the r
 edox regulatory mechanisms used to control its production\n\nJoin us at th
 is 4 o'Clock Forum to hear from Professor Ryan Joshua Mailloux\, Director 
 of McGill's School of Human Nutrition discuss how cells make and regulate 
 hydrogen peroxide to communicate with each other.\n\nAbout the speaker\n\n
 Professor Mailloux has established himself as a prominent mitochondrial bi
 oenergeticist and redox biologist. His current research focuses on definin
 g the major sources of mitochondrial hydrogen peroxide (mH2O2)\, its role 
 in eliciting signals that are beneficial to cells\, and how reversible red
 ox modifications that are sensitive to antioxidant defense status\, like g
 lutathionylation and nitrosylation\, modulate rates of mH2O2 generation. H
 e has successfully shown enzymes like alpha-ketoglutarate dehydrogenase (K
 GDH) and pyruvate dehydrogenase (PDH) serve as vital mH2O2 sources for the
  maintenance of optimal liver health and that defects in the redox regulat
 ion of both enzymes can cause hepatic\, cardiac\, and metabolic diseases.
 \n\nHe has published 90 articles\, has an h-index of 41\, and his work has
  been cited over 5\,200 times (SCOPUS) and is an executive member of the C
 anadian Oxidative Stress Consortium.\n\nAbout the 4 o'Clock Forum Seminar 
 Series\n\nMcGill's Faculty of Agricultural and Environmental Sciences has 
 tremendous expertise and opportunities for innovations in research on agri
 culture\, the environment\, health\, food\, nutrition\, pests and parasite
 s\, including from a biotechnology perspective. However\, there are limite
 d opportunities for faculty\, postdoctoral fellows and graduate students t
 o share their common interests in these areas.\n\nIn order to bring togeth
 er the Macdonald Science Community\, we have initiated a monthly seminar s
 eries—'4 O'clock Forum'—where faculty members and postdoctoral fellows are
  invited to present their work. Through these seminars on the Macdonald ca
 mpus\, researchers and graduate students will have regular opportunities t
 o be exposed to scientific advancements related to their own fields of res
 earch as well as other scientific areas. Graduate and undergraduate studen
 ts can benefit from these academic opportunities\, all of which are aimed 
 at stimulating critical discussions about contemporary research and issues
  in the agriculture and environment\, to foster increased interactions amo
 ng the Macdonald faculty\, and to highlight our ability to deliver outstan
 ding scientific contributions.\n\nPlease jaswinder.singh [at] mcgill.ca (c
 ontact Professor Jaswinder Singh) with any questions.\n
DTSTART:20231130T210000Z
DTEND:20231130T220000Z
LOCATION:R3-048\, Raymond Building\, CA\, QC\, St Anne de Bellevue\, H9X 3V
 9\, 21111 Lakeshore Road
SUMMARY:4 o' Clock Forum: Understanding the molecular oxygen paradox
URL:https://www.mcgill.ca/macdonald/channels/event/4-o-clock-forum-understa
 nding-molecular-oxygen-paradox-352531
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