After deadly tremors a decade ago, Kumamoto built earthquake-resistant buildings and even trained locals in search and rescue.

Mr. Ogles, a two-term congressman, had held off primary threats before, despite controversy. But on Thursday, Charlie Hatcher, a former state agriculture commissioner, delivered an upset.

An anonymous reader quotes a report from The Guardian: Scientists have made the first viruses designed by artificial intelligence in a milestone that raises hopes for new medicines but also concerns over how to ensure the technology remains safe. The viruses are specific kinds known as bacteriophages, which only infect bacteria and are used around the world to treat patients with persistent infections. In lab tests, a cocktail of the AI-designed viruses killed E coli bugs that were resistant to natural bacteriophages. Dr Brian Hie, a chemical engineer at Stanford University in California, used genome language models, the genetic equivalent of the large language models behind AI chatbots, to design functioning genomes for bacteriophages. The viruses were then made in the laboratory and pitted against E coli in a dish. The ability to "rapidly design" genomes and tune them for specific bugs while overcoming resistance could "transform phage therapy" and "expand biotechnological toolkits," the researchers wrote in the journal Science. But beyond the potential benefits, the scientists said the work raised "important biosafety, biocontainment and biosecurity considerations" and urged others who were designing whole genomes to "consult both safety and security professionals throughout the project." In an accompanying article, Prof Tom Inglesby and Dr Moritz Hanke at the Center for Health Security at Johns Hopkins University in Baltimore, reinforced the warning, writing: "Although this is promising for life sciences applications, it also raises urgent biosafety and biosecurity questions. The ability to compose viral genomes using generative AI now exists; the governance to safely steer it does not." Tom Ellis, a professor of synthetic genome engineering at Imperial College London, said the work was impressive, but revealed how hard it would be to make more complex genomes. "This is literally the smallest and easiest genome to make," he said. An AI trained on the genetic code of dangerous bugs could be used to design more harmful viruses, Ellis said, but controlling access to genetic data and having restrictions on making genomes that look dangerous would help. "Governments are working hard to do this already," he added. "But honestly," he said, "the threat from full AI design and writing of a genome of a virus or bacteria is very overblown when we consider that just taking existing pathogens and making gain-of-function changes to their genomes is so much easier and much more likely to be a real pathogenic threat." Dr Filippa Lentzos, a reader in science and international security at King's College London, said the most important point to intervene at the moment was when DNA was being manufactured. "It's important to see the bigger governance picture and not focus regulation solely on the AI model," she said. "A layered approach makes more sense: safeguards around model development and access, responsible research review, synthesis screening, and established laboratory biosafety and biosecurity."

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The penalty, imposed by a state judge, is on top of a $375 million fine ordered by a jury that found Meta misled users about the safety of its platforms.

The constitutional right against self-incrimination has been invoked on several occasions during high-profile — and contentious — hearings.

Senator Marsha Blackburn easily beat two Republican rivals and is now favored to become the state’s first female governor after the November elections.

The orders come after the Supreme Court ruled June 30 that President Trump’s previous efforts to end birthright citizenship were unconstitutional.

A New Mexico court ordered (PDF) Meta to create a $567 million fund to address harms linked to youth mental health and child sexual exploitation after finding its platforms constituted a public nuisance. "In sum, the Court finds that New Mexico is in the midst of a teen mental health crisis affecting public health and public safety in and throughout the state, and that Meta's platforms are a significant contributing cause to the crisis," wrote Chief Judge Bryan Biedscheid in the decision. The fund comes on top of $375 million in civil penalties, though the judge declined to mandate changes to features such as infinite scroll and autoplay, citing potential First Amendment and Section 230 concerns. Tech Policy Press reports: The decision follows the second phase of in the State of New Mexico v. Meta Platforms Inc., which consisted of a bench trial. Its central question was whether Meta's platforms amounted to a public nuisance in New Mexico, and, if the court found that they did, what remedy would be needed to address it. In March, a Santa Fe jury found Meta liable for violations of New Mexico's Unfair Practices Act, awarding $375 million in civil penalties. The jury deliberated less than a day following that nearly seven-week trial. The $567 million abatement fund would be in addition to the civil penalties, according to today's decision. New Mexico Attorney General Raul Torrez sued Meta in December 2023, alleging the company made false public statements about the safety of its platforms while knowing internally that its products facilitated child sexual exploitation. The court denied Meta's Section 230 defense in May 2024. In today's decision, the court again asserted that "Section 230 does not preclude the State's public nuisance claim," but the decision attempted to thread the needle on issues that the court determined might have run "afoul" of the statute, or of the First Amendment, such as issuing remedies around any particular product feature.

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Scientists trained artificial intelligence on libraries of DNA and then asked the model to create recipes for viral genomes. Sixteen of them were viable, yielding new viruses.

Two Republican lawmakers have endorsed a primary opponent of Representative Cory Mills, who has been accused of assault and is under investigation by the House Ethics Committee.

The U.S. is bolstering the yen, as it did with the Argentine peso. The reasons are not solely economic.

Google's $15 billion data-center project in Visakhapatnam is facing protests and legal challenges over fears that it will worsen local water shortages and disturb wildlife near the Kambalakonda sanctuary. Google says the campus will use advanced air cooling and comply with Indian law, while state officials deny that residential or rural water supplies will be tapped. Reuters reports: The southern state of Andhra Pradesh, governed by an ally of Prime Minister Narendra Modi who has hailed the project as historic and transformational, has denied allegations that the project was fast-tracked without weighing risks to water supplies and wildlife. But the growing opposition could become an early test for Google's biggest-ever India investment, which is facing several legal challenges over its impact on water supplies and proximity to a wildlife sanctuary that is home to leopards and pangolins. In recent weeks, activists and children have marched in Visakhapatnam city, holding banners saying "We cannot drink DATA" and painting handcuffs on the Google logo, social media posts show. On Sunday, Reuters attended a public gathering where activists chalked out plans for holding door-to-door awareness campaigns and beach protests in coming days. "Development should not be at the cost of livelihood of the people," Raja Rama Mohan Roy, founder of non-profit Green Visakha said at the event where he presented statistics on Visakhapatnam's stressed water supply and demand. The government says the city receives 410 million liters of water a day from its reservoirs and rivers, against a requirement of 480 million. Rationing of water supplies is common in the city with a population of 2.5 million people. [...] The state's top court on Monday asked the government to defend against allegations leveled by activist group Jal Biradari (Water Community), which says the project will strain water availability by putting stress on a nearby reservoir. The Andhra Pradesh High Court will next hear the public interest litigation on August 24.

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Canada’s prime minister laughed off Trump’s description of Canada but suggested that trade talks between the two countries are acrimonious.

What exactly is the project of the insurgent left all about?

New Jersey improperly added as many as 6,600 noncitizens to its voter rolls. Those people could now be forced out of the country.

alternative_right shares a report from The Hill: A federal judge in Mississippi ruled Wednesday that "tower dump" warrants are unconstitutional, declining to reverse a lower court decision refusing the government's request to obtain the search warrants in a series of violent crime investigations. A "tower dump" involves cellphone companies providing law enforcement with access to the time and location data of all mobile devices connected to specific cell towers during a designated time window. Law enforcement had sought approval for several of these search warrants as part of criminal investigations into gang-related activity in the Jackson, Miss., area last year, arguing the data could help identify all those potentially involved, particularly in incidents with unknown suspects. A magistrate judge denied the applications, holding that "tower dumps" are impermissible general warrants. The district judge agreed. The order repeatedly referenced the Supreme Court's recent decision in Chatrie v United States, in which the majority held that geofence warrants require constitutional privacy protections. "With this information, the Government asserts that it will be able to identify all potential suspects," Judge Carlton Reeves wrote in a 30-page order (PDF). "Even so, law enforcement would also have access to the cellular records of countless individuals, the vast majority of whom were merely passing by a location at the 'wrong' time." "That is an unreasonable search under the Fourth Amendment," the judge concluded.

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The administration will impose a minimum import price for polysilicon, a key component for semiconductors and solar panels, as well as tariffs for products made with the material.

Dr. Anthony Fauci had refused to answer questions at a hearing last week, invoking the Fifth Amendment. Republicans argued he wasn’t entitled to that protection because he had a presidential pardon.

For an audience that grew to more than a million followers, she challenged assumptions about how people with serious illnesses should look and live.

Microsoft Azure CTO Mark Russinovich used Claude to build a gloriously impractical setup that runs Doom in the background and pastes each rendered frame into Microsoft Paint through the Windows clipboard. The project is referred to as "DoomPaint" or "MS Paint Doom" on GitHub. The Register reports: To be clear, Microsoft Paint isn't doing anything other than serving as a place to paste from the game. [...] ViZDoom runs the Doom .wad file and renders it headlessly. Each frame is passed through the Windows clipboard and pasted onto Paint's canvas. A low-level keyboard hook captures and swallows game inputs while Paint is in the foreground, and sound effects come from the game engine. A glance at the code shows Russinovich was more than happy to use Claude to whip it up. In a LinkedIn post, he said: "I've been using Fable 5 on serious research projects and find it a noticeable improvement over Opus 4.8." Using Microsoft Paint as a display for Doom is not, however, a serious research project, as Russinovich acknowledged. "I've also been having fun with it on frivolous ones," he added, so here we are. "Paint renders the game but does not compute it," said Russinovich. "Paint computes nothing. Paint has never computed anything. That's the joke."

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