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The 2019 Annual IPN Retreat will be held on September 19 & 20 at New Residence Hall (McGill University). The two-day neuroscientific meeting will the ideal niche for its students and investigators to meet up and experience intellectual stimulation and to initiate collaborations. The Retreat will commence with a keynote lecture by Dr. Timothy Murphy, Professor of Psychiatry at the University of British Columbia. He will discuss his lab's innovative research on mesoscale functional connectivity in the mouse brain. The Retreat will also feature four symposia, led by IPN Principal Investigators and students, that will explore topics related to cellular and systems neuroscience, neuroimaging and artificial intelligence. There will also be a career-oriented panel discussion, a professional development workshop, and social events during which the attendees can meet and build connections with fellow academics and peers.
Note: IPN respects McGill's mandate on sustainability in regards to environmental impact. Therefore, we encourage all our attendees to bring their own reusable water bottles, as no plastic bottles will be provided at the event. Furthermore, be sure to download the program and abstract booklet onto your smartphones, as these materials will not be handed out in hard copies at the venue.
Read through our abstract_booklet.pdf
Browse through our event gallery here
“Event triggered and resting state imaging of mesoscale functional connectivity in mouse brain"
Speaker: Dr. Timothy Murphy (University of British Columbia)
We report a fully automated homecage-based system that identifies, weighs, head-fixes, and rewards mice while permitting the collection of mesoscale functional connectivity data using genetically encoded indicators. A chronic recording system integrates wide-field intracellular calcium functional imaging and multi-site sub-cortical cellular electrophysiology in head-fixed awake behaving mice. To evaluate neuro-correlates of social behaviour, we employ mouse mesoscale GCaMP imaging to establish how brain functional networks cooperate between two simultaneously imaged GCaMP6S mice. A recurring theme in datasets from these mesoscale assessment methods is engagement of wide-scale cortical regions during even relatively simple licking tasks. Furthermore, simultaneous measurement of mouse behavior and mesoscale brain imaging revealed that body movements contribute significantly to much of on-going and task related brain activity in awake mice. New approaches to real-time assessment and closed-loop feedback based on behavioral features or brain activity will be discussed in the lecture.
Dr. Timothy Murphy is a Professor in the Department of Psychiatry at the University of British Columbia (Vancouver, Canada). He completed his Ph.D. in Pharmacology and his post-doctoral fellowship in Neuroscience, both at the Johns Hopkins School of Medicine. Dr. Murphy now has his own laboratory that is dedicated to understanding how cortical activity impacts normal brain function and diseases of the nervous system. The lab contributes to understanding how mouse cortex adapts after stroke, resulting in remapping of brain function from damaged to surviving areas using mouse models. Dr. Murphy’s lab has developed new imaging and optogenetic tools that have parallels to human brain imaging and stimulation tools. This cutting-edge research has earned Dr. Murphy many awards and funding from CIHR, Brain Canada Foundation, Canadian Stroke Network, and more.
This year's Retreat was undertaken thanks in part to funding/sponsorships from the following organizations:
For more information/questions, please contact Dhabisha Kohilanathan (projects.ipn [at] mcgill.ca).