Funded Projects

All people and projects who have received funding from each HBHL funding program are listed below.

Each project is tied to at least one of HBHL's research themes, labelled as follows:

  1. Neuroinformatics and Computational Modelling

  2. Mechanistic Models of Neurodegenerative Disorders

  3. Applied Cognitive Neuroscience of Brain Plasticity

  4. Population Neuroscience and Brain Health

Discovery Fund for Interdisciplinary Research

For this first competition in Fall 2017, each of the four HBHL Research Themes was invited to submit an application based on a series of workshops held in Summer 2017 in which research priorities were identified. A panel of 14 peer-reviewers from primarily international universities was established based on lists of potential reviewers provided by all applicants. 3-4 reviewers evaluated each application and provided scores and comments. Applicants were requested to provide written responses to the reviewers' comments to improve the proposals. Reviewer comments and applicant responses were discussed by the HBHL Strategic Steering Committee, who approved funding for all four applications. Individuals expressing conflicts of interest withdrew themselves from evaluations and discussions as necessary. Funds were disbursed starting in Spring 2018.

Theme Applicant Co-applicants Collaborators Project title Funding received
(over 3 years)
1

Bratislav Misic 

  • Doina Precup (McGill)
  • Celia Greenwood (McGill)
  • Alan Evans (McGill)
  • Jean-Baptiste Poline (McGill)

 

 

  • Alain Dagher (McGill)
  • Julien Doyon (McGill)
  • Lana Vasung (Harvard University)
  • Pedro Valdes Sosa (Cuban Neurosciences Centre)
  • Michael Hawrylycz (Allen Institute)
  • Lesley Fellows (McGill)
  • Michael Meaney (McGill)
  • Karim Jerbi (Université de Montréal)
  • Yasser Iturria-Medina (McGill)

Integrative analytics for multi-modal, multi-scale neuroscience

$1,500,000

2

Alain Dagher

  • Edward Fon (McGill)
  • Thomas Durcan (McGill)
  • Peter McPherson (McGill)
  • Ziv Gan-Or (McGill)
  • Mallar Chakravarty (McGill)
  • Louis Collins (McGill)
  • Ronald Postuma (McGill)
  • Stefano Stifani (McGill)
  • Gerhard Multhaup (McGill)
  • Kelvin Luk (University of Pennsylvania)
  • Bratislav Misic (McGill)
A platform for biocomputational models of neurodegenerative disease $1,499,430
3

Julien Doyon

  • Robert Zatorre (McGill)
  • Sylvain Baillet (McGill)
  • Mallar Chakravarty (McGill)
  • Étienne de Villers Sidani (McGill)
  • Lesley Fellows (McGill)
  • Madeleine Sharp (McGill)
  • Julie Carrier (Université de Montréal)
  • Adrian Owen (Western University)
  • Geneviève Albouy (KU Leuven)
  • Philippe Albouy (McGill)
  • Emily Coffey (Eberhard Karls Universität Tübingen) 
  • Nir Grossman (Imperial College London)
  • Bradley King (KU Leuven)
  • Bratislav Misic (McGill)
  • Stephan Swinnen (KU Leuven)

 

 

Brain plasticity mediating improved memories through online and offline stimulation methods in healthy adults and patients with a chronic neurological condition

$1,499,850

4

Michael MacKenzie

  • Laurence Kirmayer (McGill)
  • Xiangfei Meng (McGill)
  • Sonia Lupien (Université de Montréal)
  • Kieran O’Donnell (McGill)
  • Isabelle Ouellet-Morin (Université de Montréal)
  • Michael Kobor (University of British Columbia)
  • Gerald McKinley (Western University)
  • Gustavo Turecki (McGill)
  • Robert Hemmings (McGill)
  • Celia Greenwood (McGill)
  • Tuong-Vi Nguyen (McGill)
  • Amy Bombay (Dalhousie University)
  • Candice Odgers (University of California, Irvine)
  • Carl D’Arcy (University of Saskatchewan)
  • Hymie Anisman (Carlton University)
  • Kimberly Matheson (Ottawa Institute of Mental Health)
  • Anita Benoit (University of Toronto)
  • Robyn Jane McQuaid (Royal Institute of Mental Health)
  • Mindy Denny (Union of Nova Scotia Indians)
Translational neuroscience and Canadian society $1,499,270

Innovative Ideas

An open competition was launched in Fall 2017, for which 85 Letters of Intent (LOIs) were submitted. The LOIs were evaluated by 12 members of the HBHL Research Management Committee as well as three external reviewers, with 4-5 reviewers evaluating each LOI. Each evaluation consisted of a score out of 100 based on provided criteria, which were converted to z-scores to normalize between evaluators. The Research Management Committee invited the top 22 LOIs to submit a full application. 

All 22 applicants submitted a full application. A panel of 25 national and international evaluators, none of which were from McGill, was convened based on lists of potential reviewers provided by all applicants. Each application received at least 4 reviews. Any reviewer who had co-authored a publication with an applicant within the past 6 years, or self-reported conflict of interest, was excluded from reviewing the relevant application(s). An average score for each application was calculated based on all of its evaluations, and presented to the HBHL Research Management Committee in an anonymized fashion, i.e., the names of Applicants, co-Applicants and collaborators, and the project titles were removed. The HBHL Research Management Committee recommended funding of the top 12 applications ranked on average total scores. The HBHL Strategic Steering Committee (having access to the same anonymized scores) approved funding for these 12 applications. Funds were disbursed starting in Spring 2018. Projects are listed below in alphabetical order by applicant surname.

Theme

Applicant

Co-applicants         

Collaborators Project title Funding received (over 2 years)
1 Alan Evans

Yoshua Bengio (Université de Montréal)

 

 

  • Konrad Wagstyl (University of Cambridge)
  • Adriana Romero (Université de Montréal)
  • Joseph Cohen (Université de Montréal)
  • Katrin Amunts (Forschungszentrum Jülich)
  • Timo Dickscheid  (Forschungszentrum Jülich)

Deep learning approaches to tackle neuroimaging challenges

 $161,500 

2 Edith Hamel

Frédéric Lesage (Université de Montréal)

Christophe Grova (Concordia)

Brain hemodynamic signals as a dynamic biomarker of dementia initiation, progression and treatment

 $170,000 

2 Timothy Kennedy
  • Christopher Barrett (McGill)
  • David Juncker (McGill)
  • Edward Fon (McGill)
  • Thomas Durcan (McGill)
  • Tanja Kuhlmann (Universitätsklinikum Münster)
  • Amir Shmuel (McGill)
  • Louis Collins (McGill)
  • Kevin Petrecca (McGill)
  • Edith Hamel (McGill)

Developing vascularized brain organoids on chips for high throughput screening

$170,000 

3 Denise Klein
  • Michael Petrides (McGill)
  • Shari Baum (McGill)
  • Morgan Sonderegger (McGill)
  • Natalie Phillips (Concordia)
  • Edward Fon (McGill)

Understanding resilience and disease by using language and the brain to predict individual outcomes

$170,000 

4 Erica Moodie
  • Samy Suissa (McGill)
  • Christel Renoux (McGill)
  • Susan Shortreed (Kaiser Permanente)
  • Gregory Simon (Kaiser Permanente)

A personalized approach to depression care: Discovering adaptive treatment strategies

 $131,695 

3 Christopher Pack

Étienne de Villers Sidani (McGill)

  • Céline Odier (Université de Montréal)
  • Rosa Sourial (MUHC)
  • Marie-Josée Gagnon (Hôpital de réadaptation Villa Medica)
  • Robert Gordon (The Article 19 Group, Inc.)

Targeted plasticity for recovery from cortical visual impairment

 $146,356 

1 Amir Shmuel
  • Ravi Menon (Western University)
  • David Rudko (McGill)
  • Sergey Plis (University of New Mexico)
  • Corey Baron (Western University)
  • Louis Collins (McGill University)

Estimating spatially resolved microstructural features of the brain based on quantitative MRI

$170,000
2 R. Nathan Spreng
  • John Breitner (McGill)
  • Sylvia Villeneuve (McGill)
  • Judes Poirier (McGill)
  • Jean-Paul Soucy (McGill)
  • Pedro Rosa-Neto (McGill)
  • Pierre Bellec (Université de Montréal)
  • Taylor Schmitz (McGill)
  • Marc-André Bédard (UQAM)

In vivo cholinergic markers of preclinical Alzheimer’s disease progression

 $169,952 

1 David Stephens Adam Oberman (McGill)

Esteban Tabak (Courant Institute)

High complexity statistical modelling via optimal transportation

 $147,900 

1 Christine Tardif
  • David Rudko (McGill)
  • Philippe Huot (McGill)
  • Louis Collins (McGill)
  • Stephen Frey (Rogue Research Inc.)
  • Stephen Nuara (McGill)
  • Ilana Leppert (McGill)
  • Rick Hoge (McGill)
  • Michael Petrides (McGill)
  • Julien Doyon (McGill)
  • Abbas Sadikot (McGill)
  • Edward Fon (McGill)

Marmoset Magnetic Resonance Imaging platform

 $169,997 

2 Jean-Francois Trempe  
  • Thomas Durcan (McGill)
  • Edward Fon (McGill)

Measuring protein turnover in organoid and animal models of Parkinson’s disease

 $85,000 

4 Ashley Wazana
  • J. Bruce Morton (Western University)
  • Tim Oberlander (University of British Columbia)
  • Celia Greenwood (McGill)
  • Michael Meaney (McGill)
  • James Kennedy (University of Toronto)
  • Jonathan Evans (University of Bristol)
  • Henning Tiemeier (Erasmus)

When gender matters: Differential effects of prenatal adversity on the development of ADHD and related neurocognitive deficits

 $169,575 

McGill-Western Collaboration Grant

The first round of the McGill-Western Collaboration Grant (MWCG) competition launched in February 2018. A total of 23 applications were received and reviewed independently by panels from both institutions. The MWCG Working Group (representing both institutions) reviewed an anonymized list of applications, including the budget and ranking provided by evaluators, and recommended that the top seven applications receive funding. The HBHL Strategic Steering Committee and the BrainsCAN Executive Committee approved the selection, listed below. Learn more about these projects.

Theme Co-lead applicant (McGill)

Co-lead applicant
(Western)

Project team Project title Funding received
(over 3 years)*
3 Stefanie Blain-Moraes Adrian M. Owen
  • Mohamed Badawy (MNI)
  • Justin Letourneau (MNI)
  • Marat Slessarev (Victoria Hospital)
  • Teneille Gofton (University Hospital)
Establishing Neurophysiological Evidence for the Treatment of Brain Injury in Intensive Care Units.

 Total: $360,000

HBHL: $180,000

2 Mark Brandon

Lisa Saksida

  • Sylvain Williams (McGill)
  • Timothy Bussey (Western)
  • Cecilia Kramar (Western)

Identifying the neuronal activity of adult-born neurons in the dentate gyrus that supports behavioural pattern separation.

Total: $679,500

HBHL: $360,000

2 Mallar Chakravarty

Timothy Bussey

  • Rosemary Bagot (McGill)
  • Flavio Beraldo (Western)
  • Sylvain Williams (McGill)
  • Claudia Kleinman (McGill)
Integrating behavioral, imaging, and transcriptional profiling to discover the impact of midlife stress in
Alzheimer's disease.

Total: $557,900

HBHL: $422,200

2 A. Claudio Cuello

Julio Martinez-Trujillo

  • Jim Gourdon (McGill)
  • Vilceu Bordingnon (McGill)
  • Sonia Do Carmo (McGill)
  • Keith Murai (McGill)
Towards a translational model of the human-like Alzheimer pathology in a primate species.

Total: $297,800

HBHL: $204,250 

1 Neda Ladbon-Bernasconi

Ingrid Johnsrude

  • Andrea Bernasconi (McGill)
  • Ali Khan (Western)
  • Terry Peters (Western)
  • Jorge (Western)
  • David Steven (Western)
Multiscale analysis of structure/function relationships in temporal-lobe epilepsy

Total: $99,800

HBHL: $53,400

*One year

3 Sylvain Williams

Julio Martinez-Trujillo

  • Mark Brandon (McGill)
  • Lisa Saksida (Western)
Revealing the fundamental neuronal mechanisms underlying memory function in mice and non-human primate marmoset CA1 area of the hippocampus.

Total: $741,000

HBHL: $363,000

3 Robert Zatorre

Jessica Grahn

  • Jean-Baptiste Poline (McGill)
  • Bratislav Misic (McGill)
  • Jorn Diedrichsen (Western)
  • Joe Gati (Western)
  • Estrid Jakobsen (McGill)
  • More Regev (McGill)
  • Molly Henry (Western)
  • Virginia Penhune (Concordia)
  • Emily Coffey (Concordia)

OMMABA: The Open Multimodal Music and Auditory Brain Archive

Total: $375,171

HBHL: $178,710

Neuro-Partnerships Program

The Neuro-Partnerships Program envelope of $3.1 million is available until 2023. Under this program, Healthy Brains for Healthy Lives (HBHL) provides 1:1 matching funds for projects with a high potential impact on biopharmaceutical research through existing programs offered by the Ministère de l'Économie et de l'Innovation (MEI). Co-funding is available for up to 40% of the total project cost. MEI co-funding is available through CQDM Quantum Leap and SynergiQc programs; and the MEDTEQ Industrial Consortium for Research and Innovation in Medical Technologies. Read more about this program and the evaluation process.

Theme Applicant  MEI partner  Other partners Project title

Funding received

2 Brian Chen CQDM-SynergiQc

The Research Institute of the McGill University Health Centre (RI-MUHC)

Brain Canada

Pfizer Canada

A drug-screening platform to increase protein expression levels for the treatment of neurological disorders.

 

Total: $1,526,316

HBHL: $580,001

New Investigator Start-up Grants

Grants are awarded based on an application from the Dean of the hiring faculty. The amount is negotiated between the hiring faculty and the candidate. The HBHL portion of the start-up grant (listed below) may not constitute the full amount of the recipient's start-up funding.

Recipient Department and Faculty Funding received (over 3 years) Start date
Jean-Baptiste Poline Neurology and Neurosurgery, Faculty of Medicine $200,000 August 15, 2017
Yasser Iturria-Medina Neurology and Neurosurgery, Faculty of Medicine $300,000 August 1, 2018
Aparna Suvrathan Neurology and Neurosurgery, Faculty of Medicine $229,500 November 1, 2018
Yue Lie Computer Science, Faculty of Science $162,500 January 1, 2019
Michael MacKenzie Epidemiology & Biostatistics and Psychiatry, Faculty of Medicine $349,255 March 1, 2019
Yang Zhou Neurology and Neurosurgery, Faculty of Medicine $350,000 May 1, 2019

Fellowships

Competition 1 (Postdoctoral fellows and graduate students)

An open competition was launched in Spring 2017, for which 221 complete and eligible applications were received: 46 at the Master's level, 117 at the doctoral level, and 58 at the postdoctoral level. An evaluations committee consisting of 34 McGill faculty from diverse departments and faculties was formed. Each application was assigned to three evaluators, pre-matched to minimize conflict of interest. Each evaluator reviewed applications from the same level of study, and ranked applications relative to each other. Applicants with the highest average rankings were considered for awards. The evaluations committee recommended 38 awards. 

Nine Master's students each received $10,000 per year for 1 year. 24 doctoral students each received $15,000 per year for 1 year. Five postdoctoral fellows each received $35,000 (plus benefits) per year for 1 or 2 years.

Theme Level of study Recipient Supervisor Project title
1, 4 Master's

Saashi (Alexandra) Bedford

Mallar Chakravarty

Large scale analysis of neuroanatomical variation and sex differences in autism spectrum disorders

4

Master's

Jessica Burdo

Howard Steiger and Lea Thaler

Contributions of nutrient levels and stress exposures to DNA methylation levels in individuals with anorexia nervosa

2

Master's

Tyler Cannon

Samantha Gruenheid

Intestinal infection induces neurological dysfunction in Parkinson-susceptible hosts

3

Master's

Kaitlyn Easson

Marie Brossard-Racine

Quantifying myelin integrity in youth born with congenital heart disease

2

Master's

Ryan McPhedrain

Edward Ruthazer Characterization of different function roles of Wnt signalling at the synapse
3

Master's

Seung Hyun Min

Robert Hess

Duration dependency of monocular deprivation induced visual plasticity

3, 4

Master's

Anmol Nagpal

Nahum Sonenberg

eIF2α signaling in autism spectrum disorders

2

Master's

Edwin Wong

Timothy Kennedy

Dysregulation of netrin-1 signaling through deleted-colorectal cancer and amyloid precursor protein promotes synaptic dysfunction and neurodegeneration

2

Master's

Yang Zhang

Alyson Fournier

Neuroprotective effects and mechanisms of neuronal miR-27a in multiple sclerosis

3 Doctoral

Elizabeth Ankudowich

M. Natasha Rajah

Functional networks related to episodic memory and performance across the adult lifespan

4

Doctoral

Sarah Barnett Burns

Gustavo Turecki and Giamal Luheshi Depression as a gut feeling: Gut microbiomeregulation of the neural epigenome in hte context of early life stress induced depression
3

Doctoral

Matteo Bernabo

Karim Nader

Breaking bad memories: PKMζ in fear memory reconsolidation

1

Doctoral

Peter Donhauser

Sylvain Baillet

Novel scalable approaches to study predictive coding using human electrophysiology

3

Doctoral

Elizabeth DuPre

R. Nathan Spreng

Neural variability as a predictor of cognitive resilience

4

Doctoral

Nellie Fotopoulos

Ridha Joober and Sherif Karama

Neuroimaging study of genetic and environmental risk factors in children with ADHD

2, 4

Doctoral

Andy Gao

Anne McKinney

The role of NHE6 mutations in the pathogenesis of neurological disorders

1

Doctoral

Nuwan Hettige

Carl Ernst

Building better brains with big data to study neurodevelopmental disorders

2

Doctoral

Dorelle Hinton

Caroline Paquette

Investigating the effects of Parkinson’s Disease on the brain structures involved in complex walking: A PET study

1

Doctoral

Alexandre Hutton

Tal Arbel Machine learning for multi-modal medical image registration
4

Doctoral

Jace Jones-Tabah

Terence Hébert and Paul Clarke

Measuring G protein-coupled receptor signaling in vivo with resonance energy-based
biosensors

1

Doctoral

Gregory Kiar

Alan Evans

SCIENCE: Scalable Cloud Infrastructure Enabling Neuroscience Computation with Ease

4

Doctoral

Vincent Laliberté

Laurence Kirmayer

The neurobiological discourse in psychiatry

1

Doctoral

Carolina Makowski

Martin Lepage and Alan Evans

Probing the dysconnectivity hypothesis in early psychosis: A multi-modal model of hippocampal centrality

1

Doctoral

Philip Novosad

Louis Collins

Towards robust multi-site MRI segmentation using sparse patch-matching and corrective learning

2

Doctoral

Felix Oestereich

Lisa Munter

The role of the ‘cholesteryl ester transfer protein’ in Alzheimer’s disease

2

Doctoral

Sarah Rosen

Jeffrey Mogil

T-cell dependent reversal of allodynia in pregnant mice
2

Doctoral

Dorothee Schoemaker

Jens Pruessner

Investigation of entorhinal dysfunction in the prediction of Alzheimer’s Disease

1

Doctoral

Golia Shafiei

Bratislav Misic

Multimodal data fusion for subtyping in Parkinson’s Disease

2

Doctoral

Isabella Straub

Eric Shoubridge

The role of the mitochondrial proteins CHCHD10 and CHCHD2 in neurodegenerative disorders

4

Doctoral

Kristina Tchalova

Jennifer Bartz

Examining the neurochemical substrates of social buffering

2

Doctoral

Lianne Trigiani

Edith Hamel

Investigating the role of white matter and the endothelium in mediating the benefits of physical exercise
in a mouse model of vascular cognitive impairment

2

Doctoral

Bruno Vieira

Austen Milnerwood

Understanding acutely-induced synucleinopathy in neurons and the influence of Parkinson’s disease gene mutations

1 Postdoctoral

Boris Chaumette

Guy Rouleau

Prediction of the conversion to psychosis by integrative multi-omic analyses

2 Postdoctoral

Seyed-Mohammad Fereshtehnejad

Ronald Postuma and Alain Dagher

Completing the puzzle of Parkinson’s disease subtypes: Longitudinal analysis of clinical, imaging, biospecimen and genetic data

1

Postdoctoral

Ricardo Pizarro

Amir Shmuel

Using deep learning algorithms to automate noise identification in structural brain MRI

4 Postdoctoral

Elizaveta Solomonova

Phyllis Zelkowitz

Biological foundations of Theory of Mind and empathy: A longitudinal epigenetic, hormonal and behavioural study

2 Postdoctoral

Benoît Vanderperre

Edward Fon

The influence of novel PD‐associated endolysosomal proteins on alpha‐synuclein propagation

Competition 2 (Postdoctoral fellows)

An open competition was launched in late 2017, for which 43 complete and eligible applications were received.  An evaluations committee consisting of 9 McGill faculty from diverse departments and faculties was formed. Each application was assigned to three evaluators, pre-matched to minimize conflict of interest. Each evaluator ranked applications relative to each other, and applicants with the highest average z-score rankings were considered for awards. The evaluations committee recommended seven awards. All recipients received $60,000 (plus benefits) per year for 2 years.

Theme Recipient Supervisor Project title
2 Mari Aaltonen

Eric Shoubridge

Characterization of ER-mitochondria contact sites

1

Martin Carrier-Vallières

Jan Seuntjens

Integration of radiomics methods into convolutional neural networks for improved assessment of brain tumour aggressiveness
1 Benjamin De Leener Julien Doyon Development of an early diagnosis biomarker for Parkinson's disease: Exploring the combination of spinal cord and brain multi-parametric MRI
1 Alexandra Keinath Mark Brandon

Dissecting functional interactions within the hippocampal formation

1, 2, 4 Eric Plitman

Mallar Chakravarty

Biomarker discovery for psychosis

3 Jessica Slater

Caroline Palmer

Investigating timing deficits in ADHD with musical rhythm and neural dynamics

3

Hovy Ho Wai Wong

Jesper Sjöström

The role of axonal translation in synapse-type-specific plasticity in neocortical microcircuits

3 Maral Yeganeh Doost Lesley Fellows

Towards a neurobiological framework for rehabilitating motivational deficits after stroke

Competition 3 (Graduate students)

An open competition was launched in Spring 2018, for which 132 complete and eligible applications were received: 50 at the Master's level, and 82 at the doctoral level. An evaluations committee consisting of 24 McGill faculty from diverse departments and faculties was formed. Each application was assigned to three evaluators, pre-matched to minimize conflict of interest. Each evaluator reviewed applications from the same level of study, and ranked applications relative to each other. Applicants with the highest average rankings were considered for awards. The evaluations committee recommended 54 awards.

Twenty Master's students each received $10,000 per year for 1 year. 34 doctoral students each received $15,000 per year for 1 year.

Theme Level of study Recipient Supervisor Project title
2 Master's Heather Anderson-Keightly Frederic Charron The role of senescent cells in medulloblastoma progression
2 Master's Katrina Cruickshank Jamie Near Implications of TNFa inhibition in Alzheimer’s disease: A neuroimaging study in the TgF344-AD rodent model
3 Master's Bernat de las Heras Marc Roig Promoting brain plasticity during sub-acute stroke: The interactive role of exercise and genotype
2 Master's Alexa Derksen Genevieve Bernard Clinical, genetic, and pathophysiological characterization of non-hypomyelinating leukodystrophy
4 Master's Stefan Drakulich Sherif Karama and Alan Evans Early childhood adversity, epigenetic age acceleration, and the brain: Impacts on intelligence
3 Master's Kaitlyn Easson Marie Brossard-Racine Evaluating white matter microstructure in youth born with congenital heart disease
3 Master's Eviatar Fields Alanna Watt Understanding the cellular underpinnings of declining motor coordination in healthy ageing
3 Master's Rana Ghafouri-Azar Pia Wintermark May sildenafil repair injury to the cerebellum following neonatal hypoxia-ischemia?
1 Master's Arna Ghosh Marie-Helene Boudrias and Georgios Mitsis The use of deep learning to optimize neurorehabilitation strategies
2 Master's Manesh Girn Nathan Spreng Default-mode network resting-state dynamics in older adults with and without an elevated risk for Alzheimer’s disease
2 Master's Jacqueline Hsiao Lisa Munter Protein-protein interactions of RHBDL4 by proximity-dependent biotin identification under varying cellular conditions with analyses by mass spectrometry
1 Master's Zhenqi Liu Bratislav Misic Multimodal biotyping in psychiatric disease
2 Master's Emma MacDougall Edward Fon Rab gene expression and protein modification in PD brain models
1 Master's Victoria Madge Louis Collins Deep learning for multimodal linear registration
2 Master's Melissa McSweeney Sylvia Villeneuve Characterizing early cortical tau accumulation in late-middle-aged adults at increased risk of Alzheimer's disease
2 Master's Matthew Pilgrim Madeline Sharp Role of award sensitivity in attention deficits in Parkinson's disease
4 Master's Jose Maria Restrepo Cecilia Flores Differential effects of high and low doses of amphetamine in adolescence on resilience to stress in adulthood
3 Master's Pierre-Luc Rochon Arjun Krishnaswamy The role of sdk1 in the assembly and function of feature-detecting retinal circuits
2 Master's Chin Chia Sung Kalle Gehring Structural studies of activated Parkin
3 Master's Sonali Uttam Arkady Khoutorsky and Luda Diatchenko Investigation of gene expression mechanisms in chronic pain
2 Doctoral Fulya Akcimen Guy Rouleau and Patrick Dion Genetic analysis of restless leg syndrome
1 Doctoral Saishree Badrinarayanan Mark Brandon Role of disinhibition in the spatial navigation circuit
2 Doctoral Emily Banks Peter McPherson Unravelling the genotype/phenotype relationship of DENND5A in epileptic encephalopathy
2 Doctoral Andrew Bayne Jean-Francois Trempe Characterization of the human mitochondrial processing peptidase in Parkinson’s disease
2 Doctoral Sara Bermudez Nahum Sonenberg Altered mRNA translation in microglia implicated Alzheimer’s disease
3 Doctoral Matteo Bernabo Karim Nader Breaking bad memories: PKMζ in fear memory reconsolidation
2 Doctoral Tyler Cannon Samantha Gruenheid Gram-negative intestinal infection triggers transient parkinsonism in PINK1 knockout mice
2 Doctoral Daryan Chitsaz Tim Kennedy A novel micro-engineered culture system to unravel mechanisms underlying myelin production and pathology
3 Doctoral Christina Chou Jesper Sjöström A novel rapid plasticity mapping method
2 Doctoral Anna Cook Alanna Watt Identifying developmental disruption and potential therapeutic interventions in spinocerebellar ataxia type 6
2 Doctoral Caitlin Fowler Jamie Near A neuroimaging study of the effects of early versus late anti-inflammatory treatment in the TgF344-AD rat model of Alzheimer’s disease
3 Doctoral Isabelle Groves Oliver Hardt The role of pro-apoptotic signalling in the active decay of long-term memories
1 Doctoral Michalis Kassinopoulos Georgios Mitsis Physiological noise correction in fMRI using a fusion approach based on model-based and data-driven techniques
2 Doctoral Rahul Kumar Peter McPherson Unravelling the GTPase target of a major Amyotrophic Lateral Sclerosis gene C9orf72
3 Doctoral Christopher Lafferty Jonathan Britt Probing pathway-specific control of reward-seeking behaviour with in vivo optogenetic inductions of synaptic plasticity
4 Doctoral Malosree Maitra Gustavo Turecki Single-nucleus RNA-sequencing in the post-mortem brain in depression and suicide
1 Doctoral Ross Markello Bratislav Mišić Individualized models of network atrophy in neurodegenerative disorders
3 Doctoral Amanda McFarlan Jesper Sjöström The synaptic plasticity of seizure-controlling VIP INs
4 Doctoral Pierre-François Meyer John Breitner Timing the benefits of anti-inflammatory treatment for AD prevention
3 Doctoral Effie Pereira Jelena Ristic Characterizing adaptive and maladaptive thought patterns via individual variability in genetic factors and neural activity
2 Doctoral Blandine Ponroy Keith Murai Investigating neuron-astrocyte communication in brain development and neurodegeneration in Down Syndrome using iPSC modelling and human tissue analysis
4 Doctoral Angela Potes Soham Rej and Danielle Groleau A mixed methods randomized controlled trial of mindfulness-based stress reduction and mindful self-compassion adapted for university students experiencing psychological distress
4 Doctoral Maxwell James Ramstead Laurence Kirmayer System dynamics and looping effects in models of psychopathology
3 Doctoral Shima Rastegarpouyani Artur Kania Development of the ability to localize pain by studying DCC mutant mice and humans
4 Doctoral Aislinn Sandre Anna Weinberg The influence of familial vulnerability and gestational stress on neural markers of risk for anxiety disorders in infants
4 Doctoral Stephanie Scala Marco Leyton Mapping neural function in cocaine addiction
1 Doctoral Laura Estefany Suarez Bratislav Mišić Connectome-informed optimization of brain stimulation protocols
4 Doctoral Kristina Tchalova Jennifer Bartz Examining the neurochemical substrates of social buffering
2 Doctoral Joseph Therriault Pedro Rosa-Neto Unbiased assessment of global amyloid burden as determined by voxel-wise receiver operating characteristic curve analysis
4 Doctoral Neelima Vaddadi Jean Francois Cloutier Role of Kirrel3 in circuit formation in the brain
2 Doctoral Max Wolpert Karsten Steinhauer Second language impact on first language grammatical processing in Chinese-English bilinguals
2 Doctoral Bruno Vieira Austen Milnerwood Understanding acutely-induced synucleinopathy in neurons and the influence of Parkinson’s disease gene mutations

Knowledge Mobilization

The Knowledge Mobilization program was launched in March 2018. Applications may be submitted at any time. Applications for workshops (up to $20,000) are evaluated regularly by the HBHL management. Applications for larger projects (up to $100,000) are evaluated quarterly by an external peer-review committee.

Applicant Event/Project title Event/Project Funding received
Joseph Rochford NeuroSymposium 2019 June 21, 2019 $4,125
Eran Tal Psychiatric Illness in Canadian Youth: Mobilizing Measurement to Improve Clinical Care September 1, 2019 $99,733
Virginia Lee Reducing shift work fatigue: A web-based intervention for nurses April 1, 2019 $70,000
Lalit Srivastava Etiology, Prevention and Treatment of Mental Illnesses: the 42nd Meeting of the Canadian
College of Neuropsychopharmacology
June 12-15, 2019 $10,000
Angela Genge Fourth Annual National Clinical Trial Training Program May 23-24, 2019 $10,000
Alan Evans Global Brain Consortium Inaugural Workshop: Towards Global Brain Health May 9-10, 2019 $20,000
Claire Brown International Quantitative Super-Resolution Microscopy Course at the Neuro May 7-9, 2019 $10,000
Katherine Maurer Promoting brain health and resilience in social work students: Implementation and evaluation of a smartphone application April 1, 2019 $19,992
Suparna Choudhury 10 Years of Critical Neuroscience: New Directions in the Social, Ethical and Methodological Contexts of Brain Research April 1, 2019 $19,805
Kieran O'Donnell Maternal Mental Health Matters (MMHM) 2019 Begin Before Birth Canada May 1, 2019 $20,000
Alexey Kostikov Symposium on the Chemistry of Molecular Imaging and Radiochemistry at the CSC2019 Conference June 3, 2019 $2,000
Isabelle Cossette The Hearing-Care Platform: A dedicated ecosystem for a personalized assessment of noise-exposure & the promotion of hearing health January 1, 2019 $20,000
Caroline Palmer Complex Dynamics in Brain and Behaviour: Industrial knowledge dissemination events April 1, 2019 $8,382
Nicholas Cermakian The 2019 Canadian Chronobiology Conference: Biological rhythms in health and society May 26-28, 2019 $10,000
Bratislav Mišić Montreal Artificial Intelligence and Neuroscience (MAIN) 2018 conference and educational workshops December 9-12, 2018 $20,000
Lawrence Joseph

“Inside Out”: Film as a Medium for the Exploration of the Experience of Mental Disorder

December 1, 2018 $19,964
Marco Leyton

Department of Psychiatry’s 75th-anniversary celebration symposium

November 29, 2018 $6,112
Derek Bowie

McGill & NIPS Collaborative Workshop on Multi-scale Physiology/Imaging

October 22-23, 2018 $19,800
Jean-Baptiste Poline

Working meeting on the Interoperability of Open Neuroscience Platforms

March 21-23, 2018 $9,000
Kieran O'Donnell

World Maternal Mental Health Day 2018 - Begin Before Birth Canada symposium 

May 1, 2018 $9,000
Geneviève Bernard

Educational Conference on Leukodystrophies

June 13-17, 2018

$9,610
Caroline Palmer

Complex Dynamics in Brain and Behaviour: Knowledge dissemination with industry 

August and November 2018 $3,774
Laurence Kirmeyer

Toward a Canadian Framework for Brain Health

May 1-December 31, 2018 $19,500
Robert Zatorre

Machine Learning for the Cognitive Neurosciences

October 15-17,2018 $15,750
Tim Kennedy

Symposium, Molecules to Mind: Multiscale Imaging of Living Systems at McGill

June 12, 2018 $5,979.81
Alan Evans

INCF Congress

August 9-10, 2018 $20,000
Samuel Veissiere

Promoting Healthy Smartphone Use to Improve Cognition and Well-being

August 1, 2018-July 31, 2019 $75,017

Core Facilities and Technology Development

In November 2017, each of the HBHL Subcommittees was invited to submit one or more applications based on a series of workshops held in Summer 2017 in which research priorities were identified. 10 proposals were received and evaluated by a committee composed of McGill faculty members with extensive knowledge and experience in the operations and management of core facilities. The committee recommended funding of 8 proposals, as listed below.

Applicant(s) Initiative Funding received (over 3 years)
Nancy Mayo and Lesley Fellows Brain Health Outcomes Platform $337,000
Stefano Stifani, Mark Brandon, Sylvain Williams and Keith Murai

M3 (McGill-Mouse-Marmoset) Project

$1,620,000
Thomas Durcan and Edward Fon

The MNI Open iPSC Drug Discovery Platform (MNI-ODDP)

$1,330,000
Natasha Rajah Douglas Brain Imaging Centre $1,449,584
Julien Doyon McConnell Brain Imaging Centre $1,500,000
Jean-Baptiste Poline and Bettina Kemme NeuroHub $3,159, 000
Gustavo Turecki and Naguib Mechawar Douglas-Bell Canada Brain Bank & Translational Neuroscience Platform $1,152,673
Lesley Fellows McGill Cognitive Neuroscience Research Registry (MCNRR) $282,000
Richard Hoge Quebec Centre for High-Field Brain Imaging $220,000

Visiting Fellows

HBHL’s Visiting Fellows Program aims to foster inter-institutional exchanges for internationally recognized researchers. This program has been discontinued.

Recipient Department and Faculty Funding received Start date
Alain Dagher Neurology and Neurosurgery, Faculty of Medicine $14,000 June 1, 2017
Alan Evans Neurology and Neurosurgery, Faculty of Medicine $32,500 November 11, 2017
Brigitte Kieffer Psychiatry, Faculty of Medicine $40,000 October 1, 2017
Jesper Sjostrom Medicine, Faculty of Medicine $2,500 September 1, 2017
Alanna Watt Biology, Faculty of Science $2,500 August 1, 2017