Innovation Platforms

Based on the research strengths of the GCRC and future opportunities that will arise in the areas covered by its five strategic themes, the GCRC has developed a suite of innovation platforms featuring highly advanced technology, each managed and staffed by dedicated, highly qualified personnel. These innovation Platforms are vital to the research conducted by our members and are also available to other researchers at McGill and to external collaborators. Please contact the Platform Managers for further information.

 

Information related to Scientific Platforms Return to Work during the COVID-19 period 

 

McGill Integrated Core for Animal Modeling (MICAM)

Physical location: CMARC

The staff of the MICAM facility have planned a working schedule that fully respects the return to work guidelines of the Faculty of Medicine and McGill University, allowing for 2 m social distanciation. Wearing of PPEs is essential for many of the regular procedures. Mitra Cowan can be contacted (see below) for any information regarding the following procedures:

On-Campus Activities: Cryopreservation of sperm and embryos of mouse lines, Crispr gRNA screening, Generation new genetically modified mouse models, Genotyping of Founder animals, Rederivation of mouse lines, In Vitro Fertilization to re-establish new mouse lines

Off-Campus activities: Design of new models, Updating databases, Updating and transmitting results to PIs, Lab meetings between staff, Development of SOPs, protocols and papers, Analyzing sequencing data

Contact info:

Phone number: 514-398-7238

E-mail: mitra.cowan [at] mcgill.ca

 

Metabolomics Innovation Resource (MIR)

Physical Location: GCRC Room 401

All MIR staff will follow guidelines set out by GCRC, Faculty of Medicine, and McGill University. Described here are additional details to ensure distancing inside the facility (Cancer Pavilion room 401A and Cancer Pavilion room 726). Researchers will be required to contact Daina Avizonis (see below) for sample submission (both internal and external). A sample submission form will be provided electronically to the researcher. The form must be filled out in detail and returned electronically to Daina for review and any required clarification. After review, a sample drop off will be scheduled. All samples will be delivered on dry ice. Sample delivery will be scheduled and items received following practices that respect the rules outlined below.

During the ramp-up period, users that are trained in GC/MS or LC/MS data acquisition will not be allowed to process or collect their own data in the facility. MIR requests that users who are submitting samples, process them (sample extraction) as completely as possible prior to delivery to the facility. A detailed description of how the samples were processed and the state of extraction must accompany the samples as well any additional information for sample processing and running. Samples will be processed and data collected by the facility staff.

Trained users will collect their data electronically (as usual) or they can request that data be transferred to the “Stud-workstation” where they can process their data remotely. For facility users that require our full services (sample processing, data collection and analysis), the analyzed data will be provided electronically in the form of an excel spreadsheet by email as usual.

Contact info: Daina Avizonis

Phone numbers: O: 514-398-5199 L: 514-398-2798

E-mail: daina.avizonis [at] mcgill.ca

 

SciMap Facility

Physical location: GCRC Room 401

In response to COVID-19, we have implemented additional precautions in our core facility to ensure the health and safety of all staff and trainees. Until further notice, clients are not permitted in the facility. To reserve a mass cytometry experiment, please contact Dr. Yuhong Wei (yuhong.wei [at] mcgill.ca) for the most up-to-date information on scheduling, pricing and availability.

To submit a project request for fluorescent slide scanning, please contact Cleber Silveira Moraes (cleber.moraes [at] mcgill.ca).

 

Histology Facility

Physical location: Bellini Room 312

In response to COVID-19, we have implemented additional precautions in our core facility to ensure the health and safety of all staff and trainees.

New Project Requests: Please use the sample drop-off/pick-up basket outside room 312 for all new project requests. Make sure to include a hard-copy of your request with clearly labelled samples. Send an email to Cleber Silveira Moraes (cleber.moraes [at] mcgill.ca) and Plinio Queiroz Da Cruz (plinio.queirozdacruz [at] mcgill.ca) to notify them that your samples have been submitted, and attach an electronic version of your project request form.

Equipment reservations: Until further notice, clients are not permitted in the back room of the facility; only equipment located in the front room of the facility is available for use during designated hours and upon reservation. Equipment can be booked between the hours of 7–9:30 am, and 6:30–9 pm via Asset Panda – the whole room should be reserved (“Histology 312 Room A”). Please contact Cleber Silveira Moraes (cleber.moraes [at] mcgill.ca) for all new project requests, and for the most up-to-date information on what equipment is available for use.

Cleaning and PPE: A face mask is mandatory at all times while working in room 312. Only 1 person at a time is permitted to use equipment. All users that enter room 312 are required to disinfect their workstation before and after use. Upon leaving, please disinfect the doorknobs to the facility on your way out.

 

McGill Platform for Cellular Perturbation (MPCP)

Physical location - HUANG LAB, Biochemistry – 8th floor (McIntyre Medical Sciences Bldg)

MPCP, formerly known as Genetic Perturbation Service (GPS), will reopen the service to McIntyre/GCRC/Bellini users who have approved access to the McIntyre building. Service requests can be placed as normal through https://www.mcgill.ca/gcrc/innovation-platforms/mpcp. To avoid contact between users and Huang lab members, a temporary pickup location will be placed in Room 848 of the McIntyre, a common equipment room which is not frequently used. Pick up is only limited to once per week on Tuesdays - users are required to wear proper face mask and clean glove. Only 1 person at a time will be allowed in that room. Users will have to follow the one-way arrows to circulate on the 8th floor of McIntyre. The area will be properly cleaned/disinfected frequently during the pickup date. To further minimize the cross-building traffic, we will coordinate with users so only 1 person from GCRC or Bellini is needed to pick up the orders for all users in the buildings for the same day.

Contact info: Platform Director: Sidong Huang

Phone: 514-398-5446 Platform Manager: Erika Prando Munhoz

Email: gps.gcrc [at] mcgill.ca Platform Assistant: Connie Yang

 

Flow Cytometry Facility

Physical location: Bellini building room 337A

An approved SOP is attached. We ask PIs to read it and email us to acknowledge that they did and send us the list of their approved staff/trainees that might need to use the facility during the ramping-up period so that we can organize zoom meetings to go over the SOP and changes to our operations with them. This is mostly to make sure that those using our analyzers follow our new protocol and adhere to our floor’s rules. We won’t be training new users on the analyzers for the timebeing.

For those who require cell sorting, the method to book a sort will be similar to how it’s always been: individuals should email us to book a sort (either using our McGill email or by using the generic mcgillflow [at] gmail.com email that will forward the message to each of us) and detail the sort they want to do and when it’d be needed and we’ll book an appointment and instruct them about the procedure to enter our floor and where to leave and retrieve the samples for contactless drop-offs/pick-ups. Starting Monday June 1, Julien Leconte and Camille Stegen will be present at the Bellini on an alternate schedule (Mon-Wed-Fri/Tu-Thu; 9-5) when sorts and/or maintenances are required. We’ve also created a Slack group so that our users can quickly easily reach out to us and to each other if needed.

We’re also working on setting all the analyzers on a cloud so that users can more easily transfer their data from the instrument’s PC to their own and received a grant from the MRM to help our users to switch to the online version of FlowJo instead of relying on dongles to do their analysis to further reduce person-to-person interactions.

Contact info: Camille Stegen

Phone: 514-398-8203

Email: camille.stegen [at] mcgill.ca

http://mimmflow.weebly.com/

 

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