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DESCRIPTION:James Hanley\, PhD\n\nEmeritus Professor\n	Department of Epidemi
 ology\, Biostatistics and Occupational Health |\n	McGill University\n\nWHEN
 : Wednesday\, November 27\, 2024\, from 3:30 to 4:30 p.m.\n	WHERE: Hybrid |
  2001 McGill College Avenue\, Room 1201\; Zoom\n	NOTE: James Hanley will be
  presenting in-person\n\nAbstract\n\nIn epidemiological research\, the ind
 ividually-matched (and possibly nested) case-control study and conditional
  logistic regression are often thought of together (see their Wikipedia en
 tries). Statisticians and epidemiologists generally cite the publications 
 by Prentice & Breslow and by Breslow et al. in 1978 as the first descripti
 on and use of conditional logistic regression\, while economists cite the 
 1973 book chapter (on consumer choices) by Nobel laureate McFadden. I rece
 ntly described the until-now-unrecognized use of\, and way of fitting\, th
 is model in 1934 by Lionel Penrose and Ronald Fisher.\n\nIn this talk\, I 
 will first describe ways in which conditional logistic regression is used 
 today. I will then go back to earlier versions of the case-control study\,
  and the gradual refinements that gave it the respectability it has today.
  I will show that\, through their strategic sampling of the Quebec cohort 
 of asbestos workers\, and (more recently) of large administrative and clin
 ical databases\, McGill epidemiologists and biostatisticians played a very
  large role in its coming of age. They also connected it with a major deve
 lopment in survival analysis. The BMJ still insists on using subtitles (‘a
  cohort study’\; ‘a case-control study’) to separate and implicitly rank t
 hese study designs. I will argue that we should no longer view them as sep
 arate entities\, but as minor variations on a singular study design: THE ‘
 etiologic study.’\n\nThe talk will be non-technical\, and is aimed at all 
 who are interested in etiological research.\n\n* See: Biometrika\, https:/
 /doi.org/10.1093/biomet/asae038\n	Published: 08 August 2024\, or here: http
 s://jhanley.biostat.mcgill.ca/Reprints\n\n \n\nSpeaker bio\n\nJames Hanley
 \, an emeritus professor\, spend his first 7 working years as a biostatist
 ician in clinical trials in cancer\, and then 43 years at McGill\, startin
 g out in a department of Epidemiology and Health (later to become Epidemio
 logy and Biostatistics\, before being given its current name). He continue
 s to take an interest in ways of teaching statistics\, and in the history 
 of public health\, epidemiology\, and statistics. For more information\, p
 lease visit: https://jhanley.biostat.mcgill.ca\n\n \n
DTSTART:20241127T203000Z
DTEND:20241127T213000Z
SUMMARY:The first ‘nested case-control’ study and the first conditional log
 istic regression
URL:https://www.mcgill.ca/epi-biostat-occh/channels/event/first-nested-case
 -control-study-and-first-conditional-logistic-regression-360434
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