BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4//
BEGIN:VEVENT
UID:20260727T072624EDT-8363umZrVb@132.216.98.100
DTSTAMP:20260727T112624Z
DESCRIPTION:Olga Basso\, PhD\n\nAssociate Professor\, Department of Obstetr
 ics & Gynecology and the Department of Epidemiology\, Biostatistics & Occu
 pational Health\, McGill University\n\nImplications of using a fetuses-at-
 risk approach when fetuses are not at risk\n\nMonday\, 5 October 2015\n\n4
 :00 pm - 5:00 pm – McIntyre Medical Building\n\n3655 promenade Sir William
  Osler – Meakins – Rm 521\n\nALL ARE WELCOME\n\nSYNOPSIS:\n\nIt is accepte
 d that fetuses\, not babies\, are at risk of antepartum stillbirth\; howev
 er\, several studies examine the gestational-age- specific rates of postna
 tal endpoints (such as neonatal death) using fetuses as the denominator\, 
 rather than live births. Such fetuses-at-risk (FAR) approaches are appeali
 ng because many of the events relevant for infant health occur during pren
 atal life\, and gestational time is treated as time at risk. FAR analyses 
 also generally avoid “paradoxes” often seen when using births as the denom
 inator\, whereby exposures that are overall harmful appear protective at p
 reterm weeks. Advocates of extending the FAR approach to encompassing post
 natal outcomes claim that it provides a causal framework for perinatal epi
 demiology\, in contrast with the “conventional” formulation based on live 
 births at each week. Using simple examples\, I will show how\, when examin
 ing postnatal endpoints\, using fetuses as the denominator inevitably lead
 s to estimates that do not quite reflect the effect of length of gestation
 \, nor that of a given exposure\, on outcome. The broader issue of conditi
 oning on specific events when studying the effect of exposures in reproduc
 tive epidemiology will also be discussed.\n\nOBJECTIVES:\n\n\n	To illustrat
 e the difference between the types of denominator used in perinatal epidem
 iology to estimate gestational-age-specific rates of a given endpoint.\n	To
  highlight the implications of using fetuses as the denominator for outcom
 es that can only be ascertained after birth\n	To discuss the broader conseq
 uences of conditioning (or not) on specific events when measuring the effe
 ct of an exposure.\n\n\nBIO:\n\nOlga Basso is Associate Professor at McGil
 l University\, with a joint appointment at the Department of Obstetrics an
 d Gynecology and the Department of Epidemiology\, Biostatistics\, and Occu
 pational Health. Her main interest is in reproductive epidemiology\, with 
 a focus on trying to disentangle the contributions of complex risk factors
  on child health.  Her work addresses both substantive and methodological 
 issues.\n\n \n
DTSTART:20151005T200000Z
DTEND:20151005T210000Z
LOCATION:Room 521\, Meakins\, McIntyre Medical Building\, CA\, QC\, Montrea
 l\, H3G 1Y6\, 3655 promenade Sir William Osler
SUMMARY:Epidemiology Seminar
URL:https://www.mcgill.ca/epi-biostat-occh/channels/event/epidemiology-semi
 nar-255405
END:VEVENT
END:VCALENDAR