Michael Hier

Academic title(s): 
  • Professor, Faculty of Medicine, McGill University, Department of Otolaryngology-Head and Neck Surgery
  • Professor, Faculty of Medicine, McGill University, Department of Oncology
Michael Hier


Jewish General Hospital
Hospital title: 
Department Chief of Otolaryngology-Head and Neck Surgery : Jewish General Hospital
Awards, honours, and fellowships: 

1997-98 - Fellowships at Rush-Presbyterian-St. Luke’s Medical Center in Chicago, Illinois, U.S.A.

Clinical Interests: 
  • Head and Neck Oncology
  • Head and Neck Endocrine Surgery
  • Laser Laryngeal Surgery
  • Transoral Robotic Surgery
Language(s) spoken: 

Dr. Hier is an academic head and neck surgeon with a very strong interest in medical student and resident education as well as being an active participant in multiple facets of clinical research. He was involved in pioneering work on salivary gland transfer surgery to prevent xerostomia in association with radiation to the head and neck. Dr. Hier performs endoscopic laser laryngeal surgery at the Sir Mortimer B. Davis Jewish General Hospital and McGill University. He completed a term as head and neck Oncology Co-Chair for the Canadian Society of Otolaryngology-Head and Neck Surgery and has recently completed a term as a committee member for the education committee of the American Head and Neck Society. He remains actively involved at the national level.

Selected publications: 
  1. Grégoire B. Morand, Isabel Cardona, Sara Brito Silva Costa Cruz, Alex M. Mlynarek, Michael P. Hier, Moulay A. Alaoui-Jamali and Sabrina Daniela da Silva. Therapeutic Vaccines for HPV-Associated Oropharyngeal and Cervical Cancer: The Next De-Intensification Strategy? Int. J. Mol. Sci. 2022, 23(15), 8395; https://doi.org/10.3390/ijms23158395 July 29, 2022
  2. Turkdogan, S.; Pusztaszeri, M.; Forest, V.-I.; Hier, M.P.; Payne, R.J. Are Bethesda III Thyroid Nodules More Aggressive than Bethesda IV Thyroid Nodules When Found to Be Malignant? Cancers 2020, 12, 2563. https://doi.org/10.3390/cancers12092563
  3. Zeng PYF, Cecchini MJ, Barrett JW, Shammas-Toma M, De Cecco L, Serafini MS, Cavalieri S, Licitra L, Hoebers F, Brakenhoff RH, Leemans CR, Scheckenbach K, Poli T, Wang X, Liu X, Laxague F, Prisman E, Poh C, Bose P, Dort JC, Shaikh MH, Ryan SEB, Dawson A, Khan MI, Howlett CJ, Stecho W, Plantinga P, Daniela da Silva S, Hier M, Khan H, MacNeil D, Mendez A, Yoo J, Fung K, Lang P, Winquist E, Palma DA, Ziai H, Amelio AL, Li SS, Boutros PC, Mymryk JS, Nichols AC. Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification. EBioMedicine. 2022 Nov 25;86:104373. doi: 10.1016/j.ebiom.2022.104373. Epub ahead of print. PMID: 36442320.
  4. Malik NH, Fu R, Hainc N, Noel CW, de Almeida JR, Hosni A, Hui Huang S, Yu E, Dzioba A, Leung A, Mangat A, MacNeil D, Nichols AC, Hiremath SB, Chakraborty S, Jooya A, Gaudet M, Johnson-Obaseki S, Whelan J, Forghani R, Hier MP, Morand G, Sultanem K, Dort J, Lysack J, Matthews W, Nakoneshny S, Gill G, Globerman A, Kerr P, Maralani P, Karam I, Eskander A. Association of Primary Tumor Volume With Survival in Patients With T3 Glottic Cancer Treated With Radiotherapy: A Study of the Canadian Head & Neck Collaborative Research Initiative. JAMA Otolaryngol Head Neck Surg.. doi: 10.1001/jamaoto.2022.3996. Epub ahead of print. PMID: 36480193. 2022 Dec 8
  5. Da Silva SD, Morand GB, Diesel L, de Lima JM, Bijian K, Kailasam S, Lefebvre F, Bourque G, Hier M, Alaoui-Jamali MA. Identification of R-Spondin Gene Signature Predictive of Metastatic Progression in BRAFV600E-Positive Papillary Thyroid Cancer. Cells. 2023; 12(1):139. https://doi.org/10.3390/cells12010139
  6. Alohali S, Payne A, Pusztaszeri M, Rajab M, Forest VI, Hier M, Tamilia M, Payne R. Effect of Having Concurrent Mutations on the Degree of Aggressiveness in Patients with Thyroid Cancer Positive for TERT Promoter Mutations. Cancers (Basel). 2023 Jan 8;15(2):413.
  7. da Silva S, Morand G, Diesel L, Muniz de Lima J, Bijian K, Kailasam S, Lefebvre F, Bourque G, Hier M, Alaoui-Jamali M. Identification of R-Spondin Gene Signature Predictive of Metastatic Progression in BRAFV600E-Positive Papillary Thyroid Cancer. Cells. 2022 Dec 29;12(1):139.
  8. Psycharis SS, Salameh S, Turkdogan S, Razzaq S, Zhao K, Mascarella MA, Richardson K, Mlynarek AM, Hier MP, Sadeghi N. Prioritization of head and neck cancer patient care during the COVID-19 pandemic: a retrospective cohort study. J Otolaryngol Head Neck Surg. 2023 Feb 14;52(1):15.
  9. de Lima JM, Macedo CCS, Barbosa GV, Castellano LRC, Hier MP, Alaoui-Jamali MA, da Silva SD. E-liquid alters oral epithelial cell function to promote epithelial to mesenchymal transition and invasiveness in preclinical oral squamous cell carcinoma. Sci Rep 2023 Feb 27;13(1):3330.
  10. Bandargal S, Rajab M, Forest VI, Pusztaszeri M, Hier M, da Silva S, Payne R. Characteristics of PTEN Mutation in Thyroid Tumours: A Retrospective Chart Review. Cancers 2023, 15(5), 1575. Morand G, Eskander A, Fu R, de Almeida J, Goldstein D, Noroozi H, Hosni A, Seikaly H, Tabet P, M. Pyne J, Matthews W, Dort J, Nakoneshny S, Christopoulos A, Bahig H, Johnson-Obaseki S, Hua N, Gaudet M, Jooya A, Nichols A, Laxague F, Cecchini M, Du J, Shapiro J, Karam I, Dziegielewski P, Hanubal K, Erovic B, Grasl S, Davies J, Monteiro E, Gete M, Witterick I, Sadeghi N, Richardson K, Shenouda G, Maniakas A, Landry V, Gupta M, Zhou K, Mlynarek A, Pusztaszeri M, Sultanem K, Hier M. The protective role of postoperative radiation therapy in low and intermediate grade major salivary gland malignancies: A study of the Canadian Head and Neck Collaborative Research Initiative. (Epub – pages to come)

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