Third Annual Quebec Molecular Parasitology Symposium

Institute of Parasitology of McGill University, Macdonald Campus




Thursday, June 26, 2003, Room R2-046


9:00 - 9:10 am Introduction by Terry Spithill,
Director of the Institute of Parasitology

Welcome: Dr Deborah Buszard,
Dean, Faculty of Agricultural and Environmental Sciences


Session 1: Chair, Dr Kris Chadee


9:10 - 10:00 am Keynote speaker: Dr David Brake (introduced by Dr Spithill)
"Host-parasite encounters: an illusionary walk down immune memory lane"

(Manager, Veterinary Medicine Biological Development, Veterinary Medicine R&D, Pfizer Animal Health, Pfizer Inc.)
10:00 - 10:30 am Mary Stevenson
"Immunoregulation in malaria"
10:30 -10:45 am Coffee Break in Faculty Lounge MS 2-022
10:45 - 11:00 am Maritza Jarmillo and Martin Olivier
"Hemozoin induces murine macrophage chemokine gene expression via ERK-dependent signaling pathways: involvement of NF-B and AP-1"
11:00 - 11:30 am Tatiana Scorza, K. Grubb, P. Smooker, D. Proll and T. Spithill
"In search of cross-protective epitopes in mouse malaria models using ELI"
11:30 - 12:00 noon Indranil Dey and Kris Chadee
"Identification of a COX-like enzyme in Entamoeba histolytica and regulation of IL-8 by PGE2 in colonic epithelial cells"
12:00 - 12:15 pm Sachiko Sato
"Galectins - sweet 'chaperones' to the ball of innate immune response to Leishmania infection"
12:15 - 12:30 pm Isabelle Pelletier
"Specific recognition of Leishmania major poly-beta-galactosyl epitopes by galectin-3 and -9"


12:30 - 1:30 pm Lunch in Faculty Lounge MS 2-022


Session 2: Chair, Dr Armando Jardim


1:30 - 1:45 pm Pat Madrid and Armando Jardim
"Mapping the interaction domains Leishmania proteins LdPEX14 and LdPEX5"
1:45 - 2:00 pm Ana V. Pilar and Armando Jardim
"Interaction of Leishmania donovani LdPEX7 with LdPEX14 and LdPEX5"
2:00 - 2:30 pm Barbara Papadopoulou
"Stage-specific translational control in Leishmania"
2:30 - 2:45 pm François McNicoll and Barbara Papadopoulou
"RNA-protein interactions to identify proteins bound to conserved 3" UTR elements regulating translation"
2:45 - 3:00 pm Robert Lodge and Albert Descoteaux
"Actin cytoskeleton effector GTPase in the early stages of Leishmania donovani phagocytosis"
3:00 - 3:15 pm Mélanie Giroux and Albert Descoteaux
"Studies of the mechanism leading to the inhibition of CIITA gene expression by Leishmania donovani amastigotes"
3:15 - 3:30 pm Coffee Break in Faculty Lounge MS 2-022
3:30 - 4:00 pm Dr Danielle Légaré and Marc Ouellette
"Drug resistance mechanisms in Leishmania"
4:00 - 4:15 pm Christian Brochu and Marc Ouellette
"Antimony resistance in Leishmania"
4:15 - 4:45 pm Scott Bohle
"Heme detoxification as an antimalarial drug target"
4:45 - 5:15 pm Aamna Kaul and Joseph Dent
"The mechanism of ivermectin-induced necrotic cell death"
5:15 - 5:45 pm Poster set-up at the Ceilidh (Centennial Centre)
6:00 - 9:00 pm Poster session with dinner at the Ceilidh


Friday, June 27, 2003, Room R2-046


Session 3: Chair, Dr Paula Ribeiro


9:00 - 9:30 am Gaetan Faubert, R. Larocque, R. K. Nakagaki, P. Lee and A. Abdul-Wahid
"Oral immunization of BALB/c mice with Giardia duodenalis cyst wall protein 2 impedes cyst output"
9:30 - 10:00 am Bernadette Ardelli, Jeff Eng, Catherine Bourguinat, Mike Osei-Atweneboana, Roger Prichard
"Onchocerciasis control in jeopardy?"
10:00 - 10:15 am Daniel Galazzo and Robin Beech
"Genetic linkage and ivermectin resistance alleles in Haemonchus contortus"
10:15 - 10:30 am Joe Nabhan and Paula Ribeiro
"Structure-function studies of the proteasome regulatory particle: analysis of human and Schistosoma mansoni RPN11"
10:30 -10:45 am Coffee Break in Faculty Lounge MS 2-022
10:45 - 11:00 am M. O. Berrizbietta, M. Ndao, A. Ache, F. Vasquez and B. Ward
"Novel enzyme immunoassays for Chagas disease: comparison of assays based on whole organism vs. excretory-secretory antigen"
11:00 - 11:15 am M. Ndao, J. D. Maclean, E. Kokoskin, E. Bannayayera and B. Ward
"Malaria epidemic in Quebec, 2000"
11:15 - 12:30 am Terry Spithill: CHOPIN General Meeting and Discussion


12:30 - 1:30 pm Lunch in Faculty Lounge MS 2-022

List of Posters

  1. Fouad El-Shehabi and Paula Ribeiro: "Characterization of histamine responsive receptor in Schistosoma mansoni"
  2. Catherine Bourguinat, Jeff Eng and Roger Prichard: "The Onchocerca volvulus -tubulin genes following 12 years of control by ivermectin"
  3. Jie Liu, Joseph A. Dent, Robin N. Beech and Roger K. Prichard: "Functional analysis HcGLuCla from Haemonchus contortus in Caenorhabditis elegans"
  4. Rya Boscariol and Terry Spithill: "Cathepsin L proteases of Faciola hepatica cleaves human CD4"
  5. Cynthia Santamaria, Robin Beech and Terry Spithill: "Mining the Plasmodium falciparum genome for new merozoite surface proteins"
  6. M. Rafei, P. Lee, T. Scorza, A. Abdul-Wahid and G. Faubert: "Immunogenicity of a plasmid DNA encoding Giardia lamblia cyst wall protein 3"
  7. Shu Fen Zhou and Robin Beech: "Correlating phenotypes and genotype in invermectin resistance Haemonchus contortus L3 larvae"
  8. Darcy Moncada, Kathy Keller, David Mirelman, Serge Ankri and Kris Chadee: "Antisense inhibition of Entamoeba histolytica cysteine protease activity inhibits colonic mucin degradation"
  9. Srinivas J. Kammanadiminti and Kris Chadee: "Colonic epithelial cell responses toward Entamoeba histolytica components"
  10. Catherine Ivory and Kris Chadee: "Construction of a Gal-lectin based DNA vaccine"
  11. Celia Caballero Franco, Kathy Keller, Karen Madsen and Kris Chadee: "Probiotics enhances mucin secretion to maintain epithelial barrier function"
  12. Frédéric Dallaire and Albert Descoteaux: "The role of Rho family of GTPase in phagocytosis of Leishmania donovani"
  13. Jean-Frédéric Flandin and Albert Descoteaux: "The recognition of Leishmania donovani by a Toll-like receptor"
  14. Silvana Jananji and Albert Descoteaux: "The role of PI 3-kinase in the uptake of Leishmania donovani promastigotes"
  15. Dorothée Leduc, Valérie Menier, Francois D'Amour, John Derek, Ng Yan Hing and Albert Descoteaux: "Expression of ovalbumin in Leishmania as a model antigen to study antigen presentation"
  16. Kai-Hsin Chang and Mary Stevenson: "Inappropriately low reticulocytosis in severe malarial anemia correlates with suppression in the development of late erythroid precursors"
  17. Z. Su, K. Morgan, C. Loredo-Osti, J. and M. M. Stevenson: "Nematode infection impairs dendritic cell function leading to increased susceptibility to concurrent malaria in mice"
  18. Jean-François Marquis and Martin Olivier: "Resistance mechanisms to topoisomerase-1 inhibitors Hoechst 33342 and camptothecin in Leishmania donavani"
  19. Annie Rochette and Barbara Papadopoulou: "Characterization of a new large gene family encoding surface proteins that are differentially expressed in the intracellular form of Leishmania"
  20. Carole Dumas and Barbara Papadopoulou: "A new class of developmentally regulated non-coding RNAs possibly interacting with the spliceosomal RNP complex in Leishmania amastigotes"
  21. Marilyn Scott and Kris Koski: "Nutrition-infection interactions in a range of host-parasite associations"
  22. Aaron Kosar, Purnima Samuel and Scott Bohle: "Soluble hemes and the quinoline antimalarials"
  23. Guillaume Chatain, Lindsey McQuade and Scott Bohle: "New chloroquine and verapamil photoaffinity agents and the mechanism of the quinoline efflux and its inhibition"
  24. C. Miranda, I. Arevalo, A. Llanos, G. Matlashewski and B. Ward: "Randomized controlled trial of Imiquimod in primary therapy of cutaneous Leishmaniasis"
  25. O. Norum, M. Ndoa, M. O. Berrizbietta, N. Kelly, F. Vasquez and B. Ward: "PCR is not the gold standard for the diagnosis of Chagas disease: comparison of PCR and a novel EIA in infected monkeys"
  26. Annette Anjue and Roger Prichard: "Cloning two beta tubulin isotype cDNAs from the cattle nematode Cooperia oncophora"
  27. Anne E. Schwab and Roger K. Prichard: "Examination of SNPS associated with anthelmintic resistance in the filarial nematode Wuchereria bancrofti"
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