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Happy holiday season!

Grad. student Amani Hariri, Prof. Hanadi Sleiman, Prof. Gonzalo Cosa and coworkers have reported on the construction of surface-grafted DNA nano-tubes that exploits an assembly methodology . Single-molecule fluorescence imaging provides unique opportunities to inspect and validate the assembly structure, morphology and robustness one nanotube at a time. This work was published in Nature Chemistry.

Graduate student Anna Albertson and Assistant Professor Jean-Philip Lumb report a novel, bio-inspired approach to lignan natural products, which solves a longstanding challenge of mimicking their biosynthesis in the lab. The method provides an exceptionally efficient route to the furanolignans tanegool and pinoresinol. The work was recently published in Angewandte Chemie.

Prof. Cosa and coworkers have demonstrated that Ni2+ provides a much desired and sought after photoprotection of fluorophores in fluorescence single molecule imaging studies. Their result just appeared in J. Am. Chem. Soc.

Well done Graduates of the Class of 2015! Please join us right after convocation on June 2 for a reception in your honour.

Welcome to all new and returning students! A few McGill Chemistry Faculty enjoying the outdoor convocation ceremonies Chemistry Tuesday June 2 2015!

Watching the hidden life of materials:  Ultrafast electron diffraction experiments open a new window on the microscopic world. Grad student, Vance Morrison, Associate Professor, Brad Siwick and collaborators last contribution was released in Science on Oct 24 2014.

Deputy Minister of Industry Canada, John Knubley (center), visits the Otto Maass Chemistry building at McGill University, with Principal Suzanne Fortier (left) and recently appointed Canada Excellence Research Chair Robin Rogers on March 16 2015.

H. T. Black and D. F. Perepichka designed a supramolecular assemby using complementary hydrogen bonding between p-type dipyrrolopyridine and n-type naphthalenediimide derivatives to afford ambipolar organic semi conductors. Angew. Chem. Int. Ed. 2014, 53, 2138

Professor Robin Rogers (in red) joins McGill and becomes a Canada Excellence Research Chair in Green Chemistry. Here touring C.J. Li’s green chemistry and organic synthesis lab, with graduate student Nick Uhlig, Rosie Goldstein, VP Research and International Relations, and Senator Larry Smith. (Sept 29 2014) Photo: Owen Egan

Nobel Prize winner Akira Suzuki addresses the chemistry department on March 18 2014. Photo: Owen Egan

Prof. Parisa Ariya (left) and Prof. Jim Gleason (right) talking at "Capitalize on Convergence" event at McGill Faculty Club, December 5 2012

P450 metabolism generated a complex dynamic mixture of diastereomers. The structure identification puzzle was solved by translating numerous experimental results into a computational protocol aimed at considering all possible combinations of diastereomers to narrow it down to one. The results of Paolo Schiavini, Joshua Pottel, Nicolas Moitessier, Karine Auclair are in ChemMedChem

A recent paper in ACS Nano “Controlling Motion at the Nanoscale: Rise of the Molecular Machines”  by Ph.D. student Alex Bushuyev, with Prof. C.J. Barrett, was just named the #1 most-read paper of the entire ACS Nano Journal in the month of August.  Congratulations Alex! ACS Nano 2015, 9, 7746–7768

Despite its importance covalency of chemical bonds cannot be measured, even in principle, by experiment. A Nature Communications article by Prof. Rustam Khaliullin shows how the degree of covalency of hydrogen bonds in liquid water can be estimated quantitatively using his new theoretical method and a widely available experimental technique - nuclear magnetic resonance spectroscopy.

As part of a new venture in the Moitessier research group, recent Ph.D graduate, Josh Pottel, has delved into developing software to guide protein engineering. The findings are developments were recently published in the Journal of Chemical Information and Modeling. Read more.

DNA nanostructures are typically used as molecular scaffolds. In a publication in Nature Chemistry, grad. student Tom Edwardson and Prof. Hanadi Sleiman show that DNA structures can act as reusable templates for ‘molecular printing’ of DNA strands onto gold nanoparticles. Read more

Graduate student Yevgen Nazarenko (photo), professor Parisa Ariya and coworkers recently showed how snow sucks up pollution. This research was published in Environ. Sci.: Processes Impacts.

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A dormant singlet oxygen photosensitizer that is activated upon its reaction with reactive oxygen species (ROS) was reported by A. Durantini and coworkers in the Cosa group in J. Am. Chem. Soc. The selective production of singlet oxygen in ROS stressed vs regular cells was successfully tested via the photodynamic inactivation of stressed Gram negative Escherichia Coli strain

Congratulations Anna Alberston for securing the 2016 Udho Parsini Diwan Award for your article in Angew. Chem. Int. Ed. on lignan synthesis. Read More

Controlled payload release is one of the key elements in the creation of a reliable drug delivery system. In a recent Langmuir paper T. Noyhouzer and coworkers in both the Mauzeroll group and Canesi group (UQAM) discovered a new redox triggered drug release mechanism. Supported by in vitro assays their system demonstrated a selective release at the tumor infected sites.

On November 18 2016, Prof. Hanadi Sleiman, and 9 other researchers and scholars at McGill, will be inducted Fellow of the Royal Society of Canada. Read more.

A fluorogenic analogue of ubiquinone (Coenzyme Q10) that reversibly reports on redox reactions was reported by L. Greene and coworkers in J. Am. Chem. Soc. The probe mimics the redox and antioxidant characteristics of ubiquinone and is shown to reversibly light up upon reduction (200 fold emission enhancement), and become quenched upon oxidation.

Congratulations to CJ Li for being named fellow of the World Academy of Science

Watch cells move thanks to the research of the Wiseman group recently published in Nature Communications.

Graduate student Goeun Sim, from the van de Ven group, was selected as the Canadian finalist for the global Blue Sky Young Researchers Innovation Award. Read more

M. N. Belzile and coworkers in the Cosa group have reported in J. Am. Chem. Soc. on a fluorogenic probe emulating vitamin K redox properties to study electron transfer and transport in biological systems

Graduate student D. Polcari and coworkers from the Mauzeroll group recently published a comprehensive review of all SECM literature. Their practical guide was featured on the cover of Chemical Reviews

The Tsantrizos and Berghuis groups unravel important mechanistic insight into metabolic regulation/dysregulation with important implications for the treatment of cancer. Find out more.

McGill chemistry professor Tomislav Friščić has been awarded NSERC’s Steacie Memorial Fellowship to support his groundbreaking work on processes for making much-needed substances without the use of harmful solvents. Read more


Montreal was ranked #1 city in the world for students (source: QS Top Universities). Read more

N. Avakyan and J. Conway in the Sleiman group have reported in J. Am. Chem. Soc. that small DNA tiles associate together on lipid bilayers using pi-stacking rather than base-pairing; they produce remarkably organized patterns over micrometer length scales.

Researchers from the Moores and Barrett groups unravel the power of light to render silver nanocatalysts much more active. Read more.

R. Lincoln and coworkers in the Cosa group have reported a fluorogenic BODIPY-acrolein probe that, combined with super-resolution imaging, reports the spatiotemporal response of cells to electrophiles. Read more

Serene Bayram and Philippe Green from the Blum group demonstrated that the native fluorescence of Tobacco mosaic virus (TMV) can be used to distinguish between heavy metal ions in water.  Read more

Velvet worms produce stiff polymeric fibers from protein-lipid nanoglobules that are fully recyclable, providing scientists with an excellent role model for circular materials processing. Read more in the press release and the article in Nature Commun.

Photo credit: Alexander Bär

A new method for measuring supramolecular assembly developed in the Mittermaier and Sleiman labs and recently published in Nature Communications was selected as one of July 2018 editors’ highlights

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