Our laboratory has embraced cooperative catalysis as a general framework for the design of new enantioselective reactions. Within this regime we have exploited cooperative Lewis base/transition metal catalysis as an effective means to control and direct both reaction partners during bond construction. The versatility of this approach is such that each catalyst acts in an orthogonal manner, which permits the role and function of the metal center to be modified and tuned without compromising enantioselectivity. This seminar will describe our most recent efforts in asymmetric carbon–carbon and carbon–nitrogen bond formation.
Thomas N. Snaddon received B.Sc. (Hons.) (2003) and M.Phil. (2004) degrees from the University of Strathclyde, Glasgow, Scotland. In early 2008 he was awarded a Ph.D. from the University of Leeds, England, for research in the arena of natural product synthesis conducted under the mentorship of Professor Philip J. Kocienski, FRS. Postdoctoral appointments with Professor Alois Fürstner at the Max-Planck-Institut für Kohlenforschung in Germany (2008-2010) and Professor Steven V. Ley, FRS, at the University of Cambridge, England (2010-2013) further confirmed his broad interests in synthetic chemistry. He joined the Department of Chemistry at Indiana University in August 2013.