Microglia, critical to Alzheimer’s research, can now be produced artificially
The quest for better understanding of Alzheimer’s disease (AD) has a powerful new tool at its disposal — the ability to artificially generate brain cells that have been shown to play an important role in the disease function.
In many pathologies of the nervous system, there is a common event - cells called microglia are activated from surveillant watchmen into fighters. Microglia are the immune cells of the nervous system, ingesting and destroying pathogens and damaged nerve cells. Until now little was known about the molecular mechanisms of microglia activation despite this being a critical process in the body.