chronic pain

The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at McGill University.

Because many therapeutic options, such as opioids, for patients with chronic pain carry the risk of addiction and undesirable side effects, this breakthrough offers promising lines of research into chronic pain treatment, says Luda Diatchenko, professor at McGill’s Faculty of Dentistry and co-lead author of the new study

Classified as: chronic pain, chronic pain treatment, pain processing, Human Pain Genetics, Luda Diatchenko, Jeffrey Mogil, Faculty of Dentistry, Department of Psychology, External, faculty, staff, health and lifestyle
Published on: 8 Aug 2017

Researchers use optogenetics to produce pain relief by shutting off neurons with light

The potential of light as a non-invasive, highly-focused alternative to pain medication was made more apparent thanks to research conducted by scientists at the Montreal Neurological Institute and Hospital of McGill University and the McGill University Health Centre.

Classified as: Research, MNI, Neurology, chronic pain, analgesia, optogenetics, pain relief
Published on: 20 Apr 2016

By Cynthia Lee


In real estate, location is key. It now seems the same concept holds true when it comes to stopping pain. New research published in Nature Communications indicates that the location of receptors that transmit pain signals is important in how big or small a pain signal will be -- and therefore how effectively drugs can block those signals.

Classified as: Canadian Institutes of Health Research, pain, chronic pain, Nature Communications, health and lifestyle, spinal cord, painful stimulus, Pain treatment, glutamate receptors, National Institutes of Health, Natural Sciences and Engineering Research Council
Published on: 3 Feb 2016

By Cynthia Lee

Chronic pain may reprogram the way genes work in the immune system, according to a new study by McGill University researchers published in the journal Scientific Reports.  

Classified as: DNA, moshe szyf, medication, immune system, chronic pain, health and lifestyle, Scientific Reports, T cells, Laura Stone, white blood cells
Published on: 28 Jan 2016

A new study finds that rising placebo responses may play a part in the increasingly high failure rate for clinical trials of drugs designed to control chronic pain caused by nerve damage.

Classified as: drugs, pain, chronic pain, Jeffrey Mogil, Clinical trials, placebo, Alexander Tuttle, drug trials, pain killers
Published on: 6 Oct 2015

Insulin has long been known as the hormone which controls the body’s sugar levels: humans who lack or are insensitive to insulin develop diabetes. Although insulin is also made and released in the brain, its effects there have remained unclear.

Classified as: brain, epilepsy, chronic pain, anxiety, insulin, anesthesia, benzodiazepines, valium, psychoactive drugs
Published on: 30 Jun 2015

An international study led by scientists at McGill University reports, for the first time, that drugs that selectively target the melatonin MT2 receptor represent a novel class of analgesic drugs that could be used to treat patients with neuropathic pain.

Classified as: McGill, pain, neurons, chronic pain, melatonin, université mcgill, Gabriella Gobbi, neuropathic pain, opiods, therapy
Published on: 17 Feb 2015

“Not tonight, dear, I have a headache.” Generally speaking, that line is attributed to the wife in a couple, implying that women’s sexual desire is more affected by pain than men’s.

Classified as: pain, sex, chronic pain, female, male, mice, Mogil, sexual behaviour, sexual problems
Published on: 22 Apr 2014